Browse by ICE    |    Browse by Organism   |    Browse by ICE family
ICE family: ICEKp1
ICEKp1 is a well studied ICE. We selected it as a reference and defined ICEKp1 family. We classified any ICE that encodes an integrase gene closely related to int(ICEKp1), defined as over 60% protein homology and that has significant sequence alignment and syntenic 'core' structure into the this family.

#IDICE nameStrainReplicon
170 experimental ICEEc1Escherichia coli ECOR31-
2126 experimental ICEKp1Klebsiella pneumoniae NTUH-K2044NC_012731
3128 in_silico ICEDdaEch586-1Dickeya dadantii Ech586NC_013592
4129 in_silico ICEEcoED1a-1Escherichia coli ED1aNC_011745
5130 in_silico ICECkoBAA-1Citrobacter koseri ATCC BAA-895NC_009792
6131 in_silico ICEDzeEch1591-1Dickeya zeae Ech1591NC_012912
7132 in_silico ICEEcoUMN026-1Escherichia coli UMN026NC_011751
8180 in_silico ICEKpnHS11286-1Klebsiella pneumoniae HS11286CP003200
9374 in_silico HPI-ICEEh1Enterobacter hormaechei05-545-
experimental Data derived from experimental literature
in_silico Putative ICEs predicted by bioinformatic methods
ElementNo. of sequencesDownloadAlignment
Proteins423FastaMultiple protein sequence alignment by MUSCLE online
ICEs9Fasta Nucleotide sequence comparison by webACT
(1) Paauw A et al. (2010). Evolution in quantum leaps: multiple combinatorial transfers of HPI and other genetic modules in Enterobacteriaceae. PLoS One. 5(1):e8662. [PudMed:20084283]
(2) Wu KM et al. (2009). Genome sequencing and comparative analysis of Klebsiella pneumoniae NTUH-K2044, a strain causing liver abscess and meningitis. J Bacteriol. 191(14):4492-501. [PudMed:19447910]
(3) Lin TL et al. (2008). Characterization of integrative and conjugative element ICEKp1-associated genomic heterogeneity in a Klebsiella pneumoniae strain isolated from a primary liver abscess. J Bacteriol. 190(2):515-26. [PudMed:17981959] experimental
(4) Schubert S et al. (2004). A novel integrative and conjugative element (ICE) of Escherichia coli: the putative progenitor of the Yersinia high-pathogenicity island. Mol Microbiol. 51(3):837-48. [PudMed:14731283] experimental
experimental experimental literature