ICEberg
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ICE family: ICESa2603
ICESa2603 is a well studied ICE. We selected it as a reference and defined ICESa2603 family. We classified any ICE that encodes an integrase gene closely related to int(ICESa2603), defined as over 60% protein homology and that has significant sequence alignment and syntenic 'core' structure into the this family.

#IDICE nameStrainReplicon
176 experimental ICESde3396Streptococcus dysgalactiae subsp. equisimilis NS3396-
2233 in_silico ICESsu(BM407)2Streptococcus suis BM407NC_012926
3234 in_silico ICESsu(SC84)Streptococcus suis SC84NC_012924
4377 experimental ICESa2603Streptococcus agalactiae 2603V/RNC_004116
5378 in_silico ICESdy12394-1Streptococcus dysgalactiae subsp. equisimilis ATCC 12394CP002215
6379 in_silico ICESthJIM8232-1Streptococcus thermophilus JIM 8232FR875178
7380 in_silico ICESpa43144-1Streptococcus pasteurianus ATCC 43144NC_015600
8445 experimental ICESsu32457Streptococcus suis 32457-
experimental Data derived from experimental literature
in_silico Putative ICEs predicted by bioinformatic methods
ElementNo. of sequencesDownloadAlignment
Proteins405FastaMultiple protein sequence alignment by MUSCLE online
ICEs7Fasta Nucleotide sequence comparison by webACT
(1) Palmieri C et al. (2012). Characterization of a Streptococcus suis tet(O/W/32/O)-carrying element transferable to major streptococcal pathogens. Antimicrob Agents Chemother. 56(9):4697-702. [PudMed:22710115] experimental
(2) Palmieri C et al. (2011). Streptococcus suis, an Emerging Drug-Resistant Animal and Human Pathogen. Front Microbiol. 0.246527778. [PudMed:22275909]
(3) Haenni M et al. (2010). Diversity and mobility of integrative and conjugative elements in bovine isolates of Streptococcus agalactiae, S. dysgalactiae subsp. dysgalactiae, and S. uberis. Appl Environ Microbiol. 76(24):7957-65. [PudMed:20952646] experimental
(4) Holden MT et al. (2009). Rapid evolution of virulence and drug resistance in the emerging zoonotic pathogen Streptococcus suis. PLoS One. 4(7):e6072. [PudMed:19603075]
(5) Davies MR et al. (2009). A novel integrative conjugative element mediates genetic transfer from group G Streptococcus to other {beta}-hemolytic Streptococci. J Bacteriol. 191(7):2257-65. [PudMed:19168609] experimental
(6) Tettelin H et al. (2002). Complete genome sequence and comparative genomic analysis of an emerging human pathogen, serotype V Streptococcus agalactiae. Proc Natl Acad Sci U S A. 99(19):12391-6. [PudMed:12200547]
 
experimental experimental literature