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ICE family: PAPI-1
PAPI-1 is a well studied ICE. We selected it as a reference and defined PAPI-1 family. We classified any ICE that encodes an integrase gene closely related to int(PAPI-1), defined as over 60% protein homology and that that has significant sequence alignment and syntenic 'core' structure into the PAPI-1 family.

#IDICE nameStrainReplicon
1173 experimental pKLC102Pseudomonas aeruginosa C-
2175 experimental PAPI-1Pseudomonas aeruginosa UCBPP-PA14NC_008463
3176 experimental PAGI-5Pseudomonas aeruginosa PSE9-
4177 in_silico ICEPae2192-1Pseudomonas aeruginosa 2192-
5178 in_silico ICEPaeC3719-1Pseudomonas aeruginosa C3719-
6179 in_silico ICEPaePACS2-1Pseudomonas aeruginosa PACS2-
7235 in_silico PFGI-1Pseudomonas fluorescens Pf-5NC_004129
experimental Data derived from experimental literature
in_silico Putative ICEs predicted by bioinformatic methods
ElementNo. of sequencesDownloadAlignment
Proteins427FastaMultiple protein sequence alignment by MUSCLE online
ICEs6Fasta Nucleotide sequence comparison by webACT
(1) Carter MQ et al. (2010). The Pseudomonas aeruginosa pathogenicity island PAPI-1 is transferred via a novel type IV pilus. J Bacteriol. 192(13):3249-58. [PudMed:20363934] experimental
(2) Harrison EM et al. (2010). Pathogenicity islands PAPI-1 and PAPI-2 contribute individually and synergistically to the virulence of Pseudomonas aeruginosa strain PA14. Infect Immun. 78(4):1437-46. [PudMed:20123716] experimental
(3) Mavrodi DV et al. (2009). Mobile genetic elements in the genome of the beneficial rhizobacterium Pseudomonas fluorescens Pf-5. BMC Microbiol. 9:8. [PudMed:19144133]
(4) Mathee K et al. (2008). Dynamics of Pseudomonas aeruginosa genome evolution. Proc Natl Acad Sci U S A. 105(8):3100-5. [PudMed:18287045]
(5) He J et al. (2004). The broad host range pathogen Pseudomonas aeruginosa strain PA14 carries two pathogenicity islands harboring plant and animal virulence genes. Proc Natl Acad Sci U S A. 101(8):2530-5. [PudMed:14983043] experimental
(6) Klockgether J et al. (2004). Sequence analysis of the mobile genome island pKLC102 of Pseudomonas aeruginosa C. J Bacteriol. 186(2):518-34. [PudMed:14702321] experimental
experimental experimental literature