ICEberg
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Organism: Clostridium difficile 630
#IDICE nameICE familyReplicon
1103 experimental Tn5397Tn916NC_009089
2398 in_silico CTn1Tn916NC_009089
3399 in_silico CTn2Tn916NC_009089
4400 in_silico CTn4Tn916NC_009089
5401 in_silico CTn5Tn916NC_009089
6402 in_silico CTn6Tn916NC_009089
7403 in_silico CTn7Tn916NC_009089
experimental Data derived from experimental literature
in_silico Putative ICEs predicted by bioinformatic methods
 

ElementNo. of sequencesDownloadAlignment
ICEs7Fasta Nucleotide sequence comparison by webACT
Proteins205FastaProtein
(1) Jasni AS; Mullany P; Hussain H; Roberts AP (2010). Demonstration of conjugative transposon (Tn5397)-mediated horizontal gene transfer between Clostridium difficile and Enterococcus faecalis. Antimicrob Agents Chemother. 54(11):4924-6. [PudMed:20713671] experimental
(2) Sebaihia M; Wren BW; Mullany P; Fairweather NF; Minton N; Stabler R; Thomson NR; Roberts AP; Cerdeno-Tarraga AM; Wang H; Holden MT; Wright A; Churcher C; Quail MA; Baker S; Bason N; Brooks K; Chillingworth T; Cronin A; Davis P; Dowd L; Fraser A; Feltwell T; Hance Z; Holroyd S; Jagels K; Moule S; Mungall K; Price C; Rabbinowitsch E; Sharp S; Simmonds M; Stevens K; Unwin L; Whithead S; Dupuy B; Dougan G; Barrell B; Parkhill J (2006). The multidrug-resistant human pathogen Clostridium difficile has a highly mobile, mosaic genome. Nat Genet. 38(7):779-86. [PudMed:16804543]
(3) Wang H; Smith MC; Mullany P (2006). The conjugative transposon Tn5397 has a strong preference for integration into its Clostridium difficile target site. J Bacteriol. 188(13):4871-8. [PudMed:16788196] experimental
(4) Roberts AP; Johanesen PA; Lyras D; Mullany P; Rood JI (2001). Comparison of Tn5397 from Clostridium difficile, Tn916 from Enterococcus faecalis and the CW459tet(M) element from Clostridium perfringens shows that they have similar conjugation regions but different insertion and excision modules. Microbiology. 147(Pt 5):1243-51. [PudMed:11320127] experimental
(5) Wang H; Mullany P (2000). The large resolvase TndX is required and sufficient for integration and excision of derivatives of the novel conjugative transposon Tn5397. J Bacteriol. 182(23):6577-83. [PudMed:11073898] experimental
(6) Wang H; Roberts AP; Lyras D; Rood JI; Wilks M; Mullany P (2000). Characterization of the ends and target sites of the novel conjugative transposon Tn5397 from Clostridium difficile: excision and circularization is mediated by the large resolvase, TndX. J Bacteriol. 182(13):3775-83. [PudMed:10850994] experimental
(7) Roberts AP; Pratten J; Wilson M; Mullany P (1999). Transfer of a conjugative transposon, Tn5397 in a model oral biofilm. FEMS Microbiol Lett. 177(1):63-6. [PudMed:10436923] experimental
(8) Mullany P; Pallen M; Wilks M; Stephen JR; Tabaqchali S (1996). A group II intron in a conjugative transposon from the gram-positive bacterium, Clostridium difficile. Gene. 174(1):145-50. [PudMed:8863741] experimental
(9) Mullany P; Wilks M; Tabaqchali S (1995). Transfer of macrolide-lincosamide-streptogramin B (MLS) resistance in Clostridium difficile is linked to a gene homologous with toxin A and is mediated by a conjugative transposon, Tn5398. J Antimicrob Chemother. 35(2):305-15. [PudMed:7759394] experimental
 
experimental experimental literature