ICEberg
ICEberg ID163
NameSLP1
FamilyUnclassified
OrganismStreptomyces coelicolor A3(2)
Size (bp)17204
GC content [Genome] (%)68 [72]
Insertion sitetRNA-Tyr
FunctionCleavage of phosphorothioated DNA and methylated DNA by the type IV restriction endonuclease ScoMcrA
Species that ICE can be transferred toStreptomyces lividans
Nucleotide SequenceNC_003888 (complete ICE sequence in this genome)
Replicon chromosome (8667507 bp, Project:242) [NC_003888]
Genome coordinates5038594..5055797
Link to view genome context of this ICE in the genome browser
experimental This is a ICE derived from experimental literature.
Complete gene list of SLP1 form NC_003888
#GeneCoordinates [+/-], size (bp)Protein GI Product *
1SCO46095033984..5034847 [+], 86421222992 heat shock protein HtpX
2SCO46105034844..5035260 [+], 41721222993 hypothetical protein
3SCO46115035358..5035951 [+], 59421222994 hypothetical protein
4SCO46125036030..5037274 [-], 124521222995 amino acid transporter
5SCO46135037414..5037680 [+], 26721222996 integral membrane protein
6SCO46145037788..5038276 [-], 48921222997 putative nucleotide-binding protein
7SCO46155038758..5040125 [-], 136821222998  [UniProt]  [KEGG]integrase
8SCO46165040186..5040371 [-], 18621222999  [UniProt]  [KEGG]excisionase
9SCO46175040809..5042281 [-], 147321223000  [UniProt]  [KEGG]ATP-binding protein
10SCO46185042283..5043134 [-], 85221223001  [UniProt]  [KEGG]hypothetical protein
11SCO46195043224..5043691 [-], 46821223002  [UniProt]  [KEGG]integral membrane protein
12SCO46205043865..5045910 [-], 204621223003  [UniProt]  [KEGG]sporulation-related protein
13SCO46215045925..5046464 [-], 54021223004  [UniProt]  [KEGG]sporulation-related protein
14SCO46225046484..5046984 [-], 50121223005  [UniProt]  [KEGG]integral membrane protein
15SCO46235047012..5047170 [+], 15921223006  [UniProt]  [KEGG]hypothetical protein
16SCO46245047328..5047663 [-], 33621223007  [UniProt]  [KEGG]hypothetical protein
17SCO46255047663..5048670 [-], 100821223008  [UniProt]  [KEGG]hypothetical protein
18SCO46265048667..5049200 [-], 53421223009  [UniProt]  [KEGG]hypothetical protein
19SCO46275049197..5049466 [-], 27021223010  [UniProt]  [KEGG]hypothetical protein
20SCO46285049893..5050702 [+], 81021223011  [UniProt]  [KEGG]regulator
21SCO46295050699..5051364 [+], 66621223012  [UniProt]  [KEGG]hypothetical protein
22SCO46305051465..5052724 [-], 126032141242  [UniProt]  [KEGG]hypothetical protein
23ScoMcrA(SCO4631)5052984..5054666 [-], 168321223013  [UniProt]  [KEGG]type IV restriction endonuclease ScoMcrA
24SCO46325055828..5058728 [+], 290121223014 ATP/GTP binding protein
25SCO46335059025..5059681 [-], 65721223015 hypothetical protein
 
flank Flanking regions
integrase Gene may contribute to site-specific recombination
conjugation Gene may play role in conjugative transfer
regulation Gene may play role in regulation of transfer

ElementNo. of sequencesDownload
Nucleotide sequences1Fasta
Proteins17Fasta
(1) Liu G; Ou HY; Wang T; Li L; Tan H; Zhou X; Rajakumar K; Deng Z; He X (2010). Cleavage of phosphorothioated DNA and methylated DNA by the type IV restriction endonuclease ScoMcrA. PLoS Genet. 6(12):e1001253. [PudMed:21203499] experimental
(2) Brasch MA; Pettis GS; Lee SC; Cohen SN (1993). Localization and nucleotide sequences of genes mediating site-specific recombination of the SLP1 element in Streptomyces lividans. J Bacteriol. 175(10):3067-74. [PudMed:8387993] experimental
(3) Bibb MJ; Ward JM; Kieser T; Cohen SN; Hopwood DA (1981). Excision of chromosomal DNA sequences from Streptomyces coelicolor forms a novel family of plasmids detectable in Streptomyces lividans. Mol Gen Genet. 184(2):230-40. [PudMed:6948998] experimental
(4) Omer CA; Cohen SN (1984). Plasmid formation in Streptomyces: excision and integration of the SLP1 replicon at a specific chromosomal site. Mol Gen Genet. 196(3):429-38. [PudMed:6094971] experimental
(5) Lee SC; Omer CA; Brasch MA; Cohen SN (1988). Analysis of recombination occurring at SLP1 att sites. J Bacteriol. 170(12):5806-13. [PudMed:3056916] experimental
(6) Vogtli M; Cohen SN (1992). The chromosomal integration site for the Streptomyces plasmid SLP1 is a functional tRNA(Tyr) gene essential for cell viability. Mol Microbiol. 6(20):3041-50. [PudMed:1479893] experimental
 
experimental experimental literature