ICEberg
ICEberg ID175
NamePAPI-1
FamilyPAPI-1
OrganismPseudomonas aeruginosa UCBPP-PA14
Size (bp)107953
GC content [Genome] (%)61 [66]
Insertion sitetRNA-Lys (Lys47)
FunctionVirulence factors and regulation of biofilm formation
Species that ICE can be transferred to-
Nucleotide SequenceAY273869; CP000438 (complete ICE sequence in this genome)
Replicon chromosome (6537648 bp, Project:386) [NC_008463]
Genome coordinates5251440..5359392
Link to view genome context of this ICE in the genome browser
experimental This is a ICE derived from experimental literature.
Complete gene list of PAPI-1 form CP000438
#GeneCoordinates [+/-], size (bp)Protein GI Product *
1PA14_589005246954..5251207 [+], 4254115587794 Large exoprotein
2PA14_589105251580..5252446 [+], 867115587795  [UniProt]  [KEGG]chromosome partitioning related protein
3PA14_589205252505..5253185 [+], 681115587796  [UniProt]  [KEGG]conserved hypothetical protein
4PA14_589305253182..5253679 [+], 498115587797  [UniProt]  [KEGG]conserved hypothetical protein
5PA14_589405253676..5253825 [+], 150115587798  [UniProt]  [KEGG]hypothetical protein
6PA14_589505253822..5254508 [+], 687115587799  [UniProt]  [KEGG]conserved hypothetical protein
7PA14_589605254508..5255209 [+], 702115587800  [UniProt]  [KEGG]hypothetical protein
8PA14_589705255206..5255913 [+], 708115587801  [UniProt]  [KEGG]putative phage protein
9PA14_589805255897..5256121 [+], 225115587802  [UniProt]  [KEGG]conserved hypothetical protein
10PA14_589905256118..5257464 [+], 1347115587803  [UniProt]  [KEGG]Putative DNA helicase
11PA14_590005257636..5258163 [+], 528115587804  [UniProt]  [KEGG]conserved hypothetical protein
12PA14_590105258160..5258417 [+], 258115587805  [UniProt]  [KEGG]conserved hypothetical protein
13PA14_590205258410..5258904 [+], 495115587806  [UniProt]  [KEGG]hypothetical protein
14PA14_590305258897..5259130 [+], 234115587807  [UniProt]  [KEGG]hypothetical protein
15PA14_590505259130..5260146 [+], 1017115587808  [UniProt]  [KEGG]conserved hypothetical protein
16PA14_590605260143..5260397 [+], 255115587809  [UniProt]  [KEGG]hypothetical protein
17PA14_590705260394..5262133 [+], 1740115587810  [UniProt]  [KEGG]conserved hypothetical protein
18PA14_590905262161..5262928 [+], 768115587811  [UniProt]  [KEGG]conserved hypothetical protein
19PA14_591005262925..5264250 [+], 1326115587812  [UniProt]  [KEGG]conserved hypothetical protein
20PA14_591105264247..5264522 [+], 276115587813  [UniProt]  [KEGG]hypothetical protein
21PA14_591205264513..5264752 [+], 240115587814  [UniProt]  [KEGG]hypothetical protein
22PA14_591305265022..5265750 [+], 729115587815  [UniProt]  [KEGG]conserved hypothetical protein
23PA14_591405265756..5266289 [+], 534115587816  [UniProt]  [KEGG]conserved hypothetical protein
24PA14_591505266303..5266773 [+], 471115587817  [UniProt]  [KEGG]putative single-stranded DNA binding protein
25PA14_591605267237..5267482 [+], 246115587818  [UniProt]  [KEGG]hypothetical protein
26PA14_591705267621..5267854 [-], 234115587819  [UniProt]  [KEGG]hypothetical protein
27PA14_591805268174..5270099 [+], 1926115587820  [UniProt]  [KEGG]topoisomerase I - like protein
28PA14_591905270173..5270643 [+], 471115587821  [UniProt]  [KEGG]hypothetical protein
29PA14_592005270777..5272666 [+], 1890115587822  [UniProt]  [KEGG]conserved hypothetical protein
30PA14_592105272663..5274636 [+], 1974115587823  [UniProt]  [KEGG]putative DNA helicase
31PA14_592205275324..5276820 [+], 1497115587824  [UniProt]  [KEGG]pyocin S5
32PA14_592305276845..5277171 [-], 327115587825  [UniProt]  [KEGG]colicin immunity protein
33pilL25277443..5278567 [+], 1125115587826  [UniProt]  [KEGG]type IV B pilus proteinVF
34pilN25278639..5280276 [+], 1638115587827  [UniProt]  [KEGG]Type IV B pilus protein
35pilO25280280..5281605 [+], 1326115587828  [UniProt]  [KEGG]type IV b pilus protein
36pilP25281595..5282128 [+], 534115587829  [UniProt]  [KEGG]type IV B pilus protein
37pilQ25282137..5283717 [+], 1581115587830  [UniProt]  [KEGG]type IV B pilus protein
38pilR25283717..5284796 [+], 1080115587831  [UniProt]  [KEGG]type IV B pilus Protein
39pilS25284818..5285348 [+], 531115587832  [UniProt]  [KEGG]type IV B pilus protein
40pilT25285345..5286286 [+], 942115587833  [UniProt]  [KEGG]type IV B pilus protein
41pilV25286291..5287619 [+], 1329115587834  [UniProt]  [KEGG]Type IV B pilus protein
42pilM25287648..5288085 [+], 438115587835  [UniProt]  [KEGG]type IV B pilus protein
43PA14_593705288357..5289001 [-], 645115587837  [UniProt]  [KEGG]hypothetical protein
44PA14_593805289000..5289566 [+], 567115587836  [UniProt]  [KEGG]conserved hypothetical protein
45PA14_593905289818..5289952 [+], 135115587838  [UniProt]  [KEGG]hypothetical protein
46PA14_594005290227..5290766 [+], 540115587839  [UniProt]  [KEGG]conserved hypothetical protein
47PA14_594105290815..5291081 [-], 267115587840  [UniProt]  [KEGG]hypothetical protein
48PA14_594305291101..5291337 [+], 237115587841  [UniProt]  [KEGG]conserved hypothetical protein
49PA14_594405291822..5292529 [+], 708115587842  [UniProt]  [KEGG]conserved hypothetical protein
50PA14_594705292765..5293115 [+], 351115587843  [UniProt]  [KEGG]hypothetical protein
51PA14_594805293173..5293808 [+], 636115587844  [UniProt]  [KEGG]conserved hypothetical protein
52PA14_594905293805..5294080 [+], 276115587845  [UniProt]  [KEGG]hypothetical protein
53PA14_595005294150..5294512 [+], 363115587846  [UniProt]  [KEGG]conserved hypothetical protein
54PA14_595105294580..5294834 [+], 255115587847  [UniProt]  [KEGG]conserved hypothetical protein
55PA14_595205294926..5295531 [+], 606115587848  [UniProt]  [KEGG]hypothetical protein
56PA14_595305295561..5297012 [+], 1452115587849  [UniProt]  [KEGG]conserved hypothetical protein
57PA14_595405297117..5299366 [+], 2250115587850  [UniProt]  [KEGG]conserved hypothetical protein
58PA14_595505299690..5300916 [+], 1227115587851  [UniProt]  [KEGG]hypothetical protein
59PA14_595605301173..5301439 [+], 267115587852  [UniProt]  [KEGG]putative transposaseVF
60PA14_595705301490..5301825 [+], 336115587853  [UniProt]  [KEGG]putative transposase
61PA14_595805301889..5303424 [+], 1536115587854  [UniProt]  [KEGG]putative transposaseVF
62PA14_595905303485..5303844 [+], 360115587855  [UniProt]  [KEGG]conserved hypothetical protein
63PA14_596005303917..5304162 [-], 246115587856  [UniProt]  [KEGG]hypothetical protein
64PA14_596105304246..5304920 [-], 675115587857  [UniProt]  [KEGG]conserved hypothetical protein
65PA14_596205305003..5305668 [-], 666115587858  [UniProt]  [KEGG]conserved hypothetical protein
66PA14_596305305679..5306710 [-], 1032115587859  [UniProt]  [KEGG]hypothetical protein
67PA14_596405307321..5308010 [+], 690115587860  [UniProt]  [KEGG]conserved hypothetical protein
68PA14_596505308021..5308776 [+], 756115587861  [UniProt]  [KEGG]conserved hypothetical protein
69PA14_596605308761..5309342 [+], 582115587862  [UniProt]  [KEGG]conserved hypothetical protein
70PA14_596705309339..5309839 [+], 501115587863  [UniProt]  [KEGG]conserved hypothetical protein
71PA14_596805309848..5310105 [+], 258115587864  [UniProt]  [KEGG]hypothetical protein
72PA14_596905310109..5312343 [+], 2235115587865  [UniProt]  [KEGG]conserved hypothetical protein
73PA14_597005312343..5313089 [+], 747115587866  [UniProt]  [KEGG]conserved hypothetical protein
74cupD15313527..5314075 [+], 549115587867  [UniProt]  [KEGG]putative fimbrial protein precursor
75cupD25314164..5314910 [+], 747115587868  [UniProt]  [KEGG]putative pili assembly chaperoneVF
76cupD45317504..5318850 [+], 1347115587869  [UniProt]  [KEGG]fimbrial subunit
77cupD55318840..5319556 [+], 717115587870  [UniProt]  [KEGG]putative pili assembly chaperone
78rcsB5319600..5320295 [-], 696115587871  [UniProt]  [KEGG]putative two component response regulator
79rcsC5320295..5323549 [-], 3255115587872  [UniProt]  [KEGG]putative kinase sensor proteinVF
80pvrR5323630..5324829 [-], 1200115587873  [UniProt]  [KEGG]two component response regulator
81PA14_598005324826..5327621 [-], 2796115587874  [UniProt]  [KEGG]kinase sensor proteinVF
82PA14_598205327953..5328603 [+], 651115587875  [UniProt]  [KEGG]conserved hypothetical protein
83PA14_598305328614..5330095 [+], 1482115587876  [UniProt]  [KEGG]putative helicase
84PA14_598405330226..5331335 [+], 1110115587877  [UniProt]  [KEGG]conserved hypothetical protein
85PA14_598455331379..5331690 [-], 312115589688  [UniProt]  [KEGG]conserved hypothetical protein
86PA14_598505331863..5332168 [+], 306115587878  [UniProt]  [KEGG]hypothetical protein
87PA14_598605332241..5332600 [+], 360115587879  [UniProt]  [KEGG]putative candidate type III effector Hop protein
88PA14_598705332597..5332836 [+], 240115587880  [UniProt]  [KEGG]conserved hypothetical protein
89PA14_598805332854..5333210 [+], 357115587881  [UniProt]  [KEGG]conserved hypothetical protein
90PA14_598905333221..5333607 [+], 387115587882  [UniProt]  [KEGG]conserved hypothetical protein
91PA14_599005333604..5334263 [+], 660115587883  [UniProt]  [KEGG]conserved hypothetical protein
92PA14_599105334260..5335144 [+], 885115587884  [UniProt]  [KEGG]conserved hypothetical protein
93PA14_599205335128..5336633 [+], 1506115587885  [UniProt]  [KEGG]conserved hypothetical protein
94PA14_599305336611..5337054 [+], 444115587886  [UniProt]  [KEGG]conserved hypothetical protein
95PA14_599405337054..5339996 [+], 2943115587887  [UniProt]  [KEGG]conserved hypothetical protein
96PA14_599505339993..5340277 [+], 285115587888  [UniProt]  [KEGG]hypothetical protein
97PA14_599605340274..5340933 [+], 660115587889  [UniProt]  [KEGG]Putative protein-disulfide isomerase
98PA14_599705340930..5341148 [-], 219115587890  [UniProt]  [KEGG]conserved hypothetical protein
99PA14_599805341357..5341788 [+], 432115587891  [UniProt]  [KEGG]hypothetical protein
100PA14_599905341788..5342726 [+], 939115587892  [UniProt]  [KEGG]conserved hypothetical protein
101PA14_600005342744..5344126 [+], 1383115587893  [UniProt]  [KEGG]conserved hypothetical protein
102PA14_600105344126..5344467 [+], 342115587894  [UniProt]  [KEGG]hypothetical protein
103PA14_600205344464..5345975 [+], 1512115587895  [UniProt]  [KEGG]conserved hypothetical protein
104PA14_600305346001..5346345 [-], 345115587896  [UniProt]  [KEGG]hypothetical protein
105PA14_600405346464..5346736 [+], 273115587897  [UniProt]  [KEGG]conserved hypothetical proteinTA
106PA14_600505346740..5347090 [+], 351115587898  [UniProt]  [KEGG]putative plasmid stablization proteinTA
107PA14_600605347532..5347834 [+], 303115587899  [UniProt]  [KEGG]hypothetical protein
108PA14_600705348012..5350435 [+], 2424115587900  [UniProt]  [KEGG]conserved hypothetical protein
109PA14_600805350432..5352363 [+], 1932115587901  [UniProt]  [KEGG]conserved hypothetical protein
110PA14_600905352790..5353305 [+], 516115587902  [UniProt]  [KEGG]hypothetical protein
111dtd5353510..5354049 [-], 540115587903  [UniProt]  [KEGG]deoxycytidine triphosphate deaminase
112PA14_601105354046..5354756 [-], 711115587904  [UniProt]  [KEGG]hypothetical protein
113dcd25354756..5355289 [-], 534115587905  [UniProt]  [KEGG]putative deoxycytidine deaminase
114PA14_601305355824..5357743 [+], 1920115587906  [UniProt]  [KEGG]conserved hypothetical protein
115PA14_601405357740..5358660 [+], 921115587907  [UniProt]  [KEGG]xerD-like putative integrase
116clpB5359875..5362439 [-], 2565115587908 clpB protein
117PA14_602005362595..5363323 [-], 729115587909 conserved hypothetical protein
118rluD5363320..5364282 [-], 963115587910 ribosomal large subunit pseudouridine synthase D
 
flank Flanking regions
integrase Gene may contribute to site-specific recombination
conjugation Gene may play role in conjugative transfer

ElementNo. of sequencesDownload
Nucleotide sequences1Fasta
Proteins114Fasta
(1) Seth-Smith HM; Fookes MC; Okoro CK; Baker S; Harris SR; Scott P; Pickard D; Quail MA; Churcher C; Sanders M; Harmse J; Dougan G; Parkhill J; Thomson NR (2012). Structure, diversity, and mobility of the Salmonella pathogenicity island 7 family of integrative and conjugative elements within Enterobacteriaceae. J Bacteriol. 194(6):1494-504. [PudMed:22247511] in_silico
(2) Carter MQ; Chen J; Lory S (2010). The Pseudomonas aeruginosa pathogenicity island PAPI-1 is transferred via a novel type IV pilus. J Bacteriol. 192(13):3249-58. [PudMed:20363934] experimental
(3) Harrison EM; Carter ME; Luck S; Ou HY; He X; Deng Z; O'Callaghan C; Kadioglu A; Rajakumar K (2010). Pathogenicity islands PAPI-1 and PAPI-2 contribute individually and synergistically to the virulence of Pseudomonas aeruginosa strain PA14. Infect Immun. 78(4):1437-46. [PudMed:20123716] experimental
(4) Mathee K; Narasimhan G; Valdes C; Qiu X; Matewish JM; Koehrsen M; Rokas A; Yandava CN; Engels R; Zeng E; Olavarietta R; Doud M; Smith RS; Montgomery P; White JR; Godfrey PA; Kodira C; Birren B; Galagan JE; Lory S (2008). Dynamics of Pseudomonas aeruginosa genome evolution. Proc Natl Acad Sci U S A. 105(8):3100-5. [PudMed:18287045]
(5) He J; Baldini RL; Deziel E; Saucier M; Zhang Q; Liberati NT; Lee D; Urbach J; Goodman HM; Rahme LG (2004). The broad host range pathogen Pseudomonas aeruginosa strain PA14 carries two pathogenicity islands harboring plant and animal virulence genes. Proc Natl Acad Sci U S A. 101(8):2530-5. [PudMed:14983043] experimental
 
experimental experimental literature
in_silico in silico analysis literature