ICEberg
ICEberg ID187
Name6180-RD.2
Family10270-RD.2
OrganismStreptococcus pyogenes MGAS6180
Size (bp)37429
GC content [Genome] (%)35 [38]
Insertion site-
FunctionVirulence: encodes cell surface anchored adhesins; R28.
Species that ICE can be transferred to-
Nucleotide SequenceCP000056 (complete ICE sequence in this genome)
Replicon chromosome (1897573 bp, Project:13887) [NC_007296]
Genome coordinates1284967..1322395
Link to view genome context of this ICE in the genome browser
in_silico This is a predicted ICE derivied from literature.
Complete gene list of 6180-RD.2 form CP000056
#GeneCoordinates [+/-], size (bp)Protein GI Product *
1valS1280313..1282961 [-], 264971803053 valyl-tRNA synthetase
2M28_Spy12971282963..1283547 [-], 58571803054 hypothetical protein
3M28_Spy12981283523..1283702 [-], 18071803055 ribosomal-protein-serine acetyltransferase
4M28_Spy12991284128..1284523 [-], 39671803056 hypothetical cytosolic protein
5M28_Spy13001284544..1284882 [-], 33971803057 hypothetical protein
6M28_Spy13011284867..1284983 [-], 11771803058 hypothetical protein
7M28_Spy13021284967..1286109 [-], 114371803059  [UniProt]  [KEGG]transposase
8M28_Spy13031286437..1287573 [-], 113771803060  [UniProt]  [KEGG]DNA integration/recombination/invertion protein
9M28_Spy13041287623..1287955 [-], 33371803061  [UniProt]  [KEGG]hypothetical protein
10M28_Spy13051288122..1288664 [-], 54371803062  [UniProt]  [KEGG]hypothetical protein
11M28_Spy13061288887..1289648 [-], 76271803063  [UniProt]  [KEGG]putative cell surface protein
12M28_Spy13071289673..1290230 [-], 55871803064  [UniProt]  [KEGG]hypothetical exported protein
13M28_Spy13081290230..1291588 [-], 135971803065  [UniProt]  [KEGG]hypothetical exported protein
14M28_Spy13091291723..1291866 [+], 14471803066  [UniProt]  [KEGG]hypothetical protein
15M28_Spy13101292034..1294349 [-], 231671803067  [UniProt]  [KEGG]membrane protein
16M28_Spy13111294364..1296865 [-], 250271803068  [UniProt]  [KEGG]DNA segregation ATPase related protein
17M28_Spy13121296886..1297296 [-], 41171803069  [UniProt]  [KEGG]hypothetical protein
18M28_Spy13131297299..1297568 [-], 27071803070  [UniProt]  [KEGG]hypothetical protein
19M28_Spy13141297587..1298537 [-], 95171803071  [UniProt]  [KEGG]hypothetical protein
20M28_Spy13151298538..1299017 [-], 48071803072  [UniProt]  [KEGG]hypothetical protein
21M28_Spy13161299025..1299276 [-], 25271803073  [UniProt]  [KEGG]hypothetical protein
22M28_Spy13171299306..1299515 [-], 21071803074  [UniProt]  [KEGG]hypothetical protein
23M28_Spy13181299559..1299831 [-], 27371803075  [UniProt]  [KEGG]hypothetical protein
24M28_Spy13191300026..1300169 [-], 14471803076  [UniProt]  [KEGG]transcriptional regulator, Cro/CI family
25M28_Spy13201300220..1300597 [-], 37871803077  [UniProt]  [KEGG]hypothetical protein
26M28_Spy13211300598..1301839 [-], 124271803078  [UniProt]  [KEGG]transcriptional regulator, Cro/CI family
27M28_Spy13221302151..1303860 [-], 171071803079  [UniProt]  [KEGG]FtsK/SpoIIIE family
28M28_Spy13231303880..1304335 [-], 45671803080  [UniProt]  [KEGG]hypothetical protein
29M28_Spy13241304338..1304643 [-], 30671803081  [UniProt]  [KEGG]hypothetical protein
30M28_Spy13251304905..1308963 [-], 405971803082  [UniProt]  [KEGG]putative cell surface protein
31M28_Spy13261309133..1311373 [-], 224171803083  [UniProt]  [KEGG]putative cell surface protein
32M28_Spy13271311466..1311858 [-], 39371803084  [UniProt]  [KEGG]hypothetical protein
33M28_Spy13281311982..1312422 [-], 44171803085  [UniProt]  [KEGG]hypothetical protein
34M28_Spy13291312580..1313014 [-], 43571803086  [UniProt]  [KEGG]transcriptional regulator, Cro/CI family
35M28_Spy13301313889..1314275 [+], 38771803087  [UniProt]  [KEGG]transcriptional regulator, Cro/CI familyTA
36M28_Spy13311314282..1314704 [+], 42371803088  [UniProt]  [KEGG]hypothetical proteinTA
37M28_Spy13321314769..1315125 [-], 35771803089  [UniProt]  [KEGG]hypothetical exported protein
38M28_Spy13331315128..1315466 [-], 33971803090  [UniProt]  [KEGG]hypothetical protein
39M28_Spy13341315463..1315756 [-], 29471803091  [UniProt]  [KEGG]hypothetical protein
40M28_Spy13351315777..1315962 [+], 18671803092  [UniProt]  [KEGG]transposase
41M28_Spy13361316468..1320961 [-], 449471803093  [UniProt]  [KEGG]R28 proteinVF
42M28_Spy13371321190..1322395 [+], 120671803094  [UniProt]  [KEGG]transcriptional regulator, AraC family
43M28_Spy13381322913..1323665 [+], 75371803095 phospho-2-dehydro-3-deoxyheptonate aldolase
44aroB1323706..1324794 [+], 108971803096 3-dehydroquinate synthase
45M28_Spy13401325063..1325221 [-], 15971803097 hypothetical protein
46M28_Spy13411325229..1325534 [-], 30671803098 hypothetical cytosolic protein
47M28_Spy13421325536..1325874 [-], 33971803099 hypothetical cytosolic protein
48M28_Spy13431325927..1326682 [-], 75671803100 SAM-dependent methyltransferase
 
flank Flanking regions
integrase Gene may contribute to site-specific recombination

ElementNo. of sequencesDownload
Nucleotide sequences1Fasta
Proteins36Fasta
(1) Sitkiewicz I; Green NM; Guo N; Mereghetti L; Musser JM (2011). Lateral gene transfer of streptococcal ICE element RD2 (region of difference 2) encoding secreted proteins. BMC Microbiol. 11:65. [PudMed:21457552] experimental
(2) Beres SB; Musser JM (2007). Contribution of exogenous genetic elements to the group A Streptococcus metagenome. PLoS One. 2(8):e800. [PudMed:17726530]
 
experimental experimental literature