ICEberg
ICEberg ID21
NameICEVchInd4
FamilySXT/R391
OrganismVibrio cholerae O139 Ind4
Size (bp)95326
GC content [Genome] (%)46.9
Insertion siteprfC
FunctionAntibiotic resistance genes: floR, strBA, sul2; Toxin-antitoxin system
Species that ICE can be transferred to-
Nucleotide SequenceGQ463141 (complete ICE sequence in this GenBank file)
Replicon-
Coordinates1..95326
Link to view genome context of this ICE in the genome browser
experimental This is a ICE derived from experimental literature.
Complete gene list of ICEVchInd4 form GQ463141
#GeneCoordinates [+/-], size (bp)Protein GI Product *
1ICEVCHIND4_0001419..613 [+], 195259156294  [UniProt] conserved domain protein
2ICEVCHIND4_0002630..1871 [-], 1242259156334  [UniProt] integrase
3ICEVCHIND4_00031873..2142 [-], 270259156335  [UniProt] conserved hypothetical protein
4ICEVCHIND4_00042145..3119 [-], 975259156321  [UniProt] conserved hypothetical protein
5ICEVCHIND4_00053215..3382 [+], 168259156329  [UniProt] hypothetical protein
6ICEVCHIND4_00063584..4027 [+], 444259156368  [UniProt] conserved hypothetical protein
7ICEVCHIND4_00074038..5210 [-], 1173259156357  [UniProt] protein UmuC
8ICEVCHIND4_00085494..6087 [+], 594259156333  [UniProt] transposase, IS3 family, interruption
9ICEVCHIND4_00096201..9179 [+], 2979259156345  [UniProt] transposase
10ICEVCHIND4_00109597..11090 [+], 1494259156318  [UniProt] iscr2 transposase
11ICEVCHIND4_001111121..12005 [+], 885259156305  [UniProt] conserved hypothetical proteinAR
12ICEVCHIND4_001212222..13436 [+], 1215259156315  [UniProt] florfenicol/chloramphenicol resistance proteinAR
13ICEVCHIND4_001313464..13769 [+], 306259156307  [UniProt] truncated helix-turn-helix multiple antibiotic resistance protein
14ICEVCHIND4_001513890..14420 [+], 531259156283  [UniProt] truncated transposase
15ICEVCHIND4_001414392..15222 [-], 831259156310  [UniProt] streptomycin resistance protein BAR
16ICEVCHIND4_001615228..16031 [-], 804259156348  [UniProt] streptomycin 3''-kinaseAR
17folP16092..16907 [-], 816259156314  [UniProt] dihydropteroate synthaseAR
18ICEVCHIND4_001817378..18991 [+], 1614259156320  [UniProt] TnpA
19ICEVCHIND4_001919334..19603 [-], 270259156319  [UniProt] ultraviolet light resistance protein B
20ICEVCHIND4_002019611..20060 [-], 450259156355  [UniProt] protein UmuD
21ICEVCHIND4_002120179..20316 [+], 138259156363  [UniProt] hypothetical protein
22ICEVCHIND4_002220699..21607 [+], 909259156302  [UniProt] exonuclease, RNase T and DNA polymerase III
23ICEVCHIND4_002321681..21995 [+], 315259156352  [UniProt] conserved hypothetical protein
24ICEVCHIND4_002422103..22990 [+], 888259156346  [UniProt] conserved hypothetical protein
25ICEVCHIND4_002523000..23599 [+], 600259156316  [UniProt] conserved hypothetical protein
26ICEVCHIND4_002623596..24180 [+], 585259156286  [UniProt] conserved hypothetical protein
27ICEVCHIND4_002724199..27876 [+], 3678259156370  [UniProt] conserved hypothetical protein
28ICEVCHIND4_002827887..29056 [+], 1170259156350  [UniProt] conserved hypothetical protein
29ICEVCHIND4_002929053..29811 [+], 759259156337  [UniProt] conserved hypothetical protein
30ICEVCHIND4_003029815..33387 [+], 3573259156327  [UniProt] type II restriction enzyme
31ICEVCHIND4_003133387..36044 [+], 2658259156301  [UniProt] conserved hypothetical protein
32ICEVCHIND4_003236061..38136 [+], 2076259156289  [UniProt] conserved hypothetical protein
33ICEVCHIND4_003338180..40831 [+], 2652259156296  [UniProt] DNA repair ATPase
34ICEVCHIND4_003440986..43136 [+], 2151259156288  [UniProt] conjugative relaxase
35ICEVCHIND4_003543185..45005 [+], 1821259156353  [UniProt] conjugative coupling factor
36ICEVCHIND4_003645015..45575 [+], 561259156354  [UniProt] conserved hypothetical protein
37ICEVCHIND4_003745562..46197 [+], 636259156340  [UniProt] putative conjugation coupling factor
38ICEVCHIND4_003846223..46501 [-], 279259156291  [UniProt] transcriptional regulator, XRE family
39ICEVCHIND4_003946498..46821 [-], 324259156325  [UniProt] conserved hypothetical protein
40traL47002..47283 [+], 282259156311  [UniProt] type IV conjugative transfer system protein TraL
41ICEVCHIND4_004147280..47906 [+], 627259156293  [UniProt] sex pilus assembly
42ICEVCHIND4_004247890..48786 [+], 897259156290  [UniProt] TraK
43ICEVCHIND4_004348789..50078 [+], 1290259156282  [UniProt] sex pilus assembly
44ICEVCHIND4_004450075..50725 [+], 651259156298  [UniProt] sex pilus assembly
45ICEVCHIND4_004550722..51108 [+], 387259156369  [UniProt] TraA
46ICEVCHIND4_004651179..52120 [+], 942259156306  [UniProt] conserved hypothetical proteinTA
47ICEVCHIND4_004752113..53051 [+], 939259156304  [UniProt] yncTA
48ICEVCHIND4_004853183..53875 [+], 693259156364  [UniProt] DsbC
49traC53875..56274 [+], 2400259156309  [UniProt] type-IV secretion system protein TraC
50ICEVCHIND4_005056267..56614 [+], 348259156332  [UniProt] conserved hypothetical protein
51ICEVCHIND4_005156598..57110 [+], 513259156287  [UniProt] conjugation signal peptidase
52ICEVCHIND4_005257121..58245 [+], 1125259156284  [UniProt] sex pilus assembly
53ICEVCHIND4_005358277..59257 [+], 981259156303  [UniProt] sex pilus assembly
54ICEVCHIND4_005459260..62958 [+], 3699259156297  [UniProt] mating pair stabilization
55ICEVCHIND4_005563051..63731 [-], 681259156358  [UniProt] hypothetical protein
56ICEVCHIND4_005663738..64823 [-], 1086259156359  [UniProt] conserved hypothetical protein
57ICEVCHIND4_005764823..65887 [-], 1065259156341  [UniProt] conserved hypothetical protein
58ICEVCHIND4_005866000..66683 [-], 684259156365  [UniProt] endonuclease-1 (Endonuclease I) (Endo I)
59ICEVCHIND4_005966816..67418 [-], 603259156326  [UniProt] conserved hypothetical protein
60ICEVCHIND4_006067655..67786 [-], 132259156313  [UniProt] hypothetical protein
61ICEVCHIND4_006167786..68112 [+], 327259156360  [UniProt] conserved hypothetical protein
62ICEVCHIND4_006268128..68547 [+], 420259156366  [UniProt] single-strand binding protein familyVF
63ICEVCHIND4_006368627..69445 [+], 819259156324  [UniProt] phage recombination protein Bet
64ICEVCHIND4_006469527..69670 [+], 144259156300  [UniProt] hypothetical protein
65ICEVCHIND4_006569731..70747 [+], 1017259156361  [UniProt] YqaJ viral recombinase family
66ICEVCHIND4_006670957..71916 [+], 960259156343  [UniProt] ATPase associated with various cellular activities, AAA_5
67ICEVCHIND4_006771919..72683 [+], 765259156328  [UniProt] conserved hypothetical protein
68ICEVCHIND4_006872782..73735 [+], 954259156285  [UniProt] conserved hypothetical protein
69ICEVCHIND4_006973797..74237 [+], 441259156312  [UniProt] conserved hypothetical protein
70ICEVCHIND4_007074307..75962 [+], 1656259156295  [UniProt] von Willebrand factor, type A
71radC76044..76541 [+], 498259156323  [UniProt] DNA repair protein RadCVF
72ICEVCHIND4_007276541..76882 [+], 342259156347  [UniProt] conserved hypothetical protein
73ICEVCHIND4_007376974..78047 [+], 1074259156317  [UniProt] phage P4 alpha, zinc-binding domain protein
74ICEVCHIND4_007478138..78845 [+], 708259156331  [UniProt] conserved hypothetical protein
75ICEVCHIND4_007579108..80037 [-], 930259156308  [UniProt] response regulator receiver protein
76ICEVCHIND4_007680043..83849 [-], 3807259156330  [UniProt] multi-sensor hybrid histidine kinaseVF
77ICEVCHIND4_007783840..83956 [+], 117259156292  [UniProt] hypothetical protein
78ICEVCHIND4_007884584..85528 [+], 945259156344  [UniProt] conserved hypothetical protein
79ICEVCHIND4_007985531..86919 [+], 1389259156367  [UniProt] sex pilus assembly
80ICEVCHIND4_008086923..90492 [+], 3570259156336  [UniProt] sex pilus assembly
81ICEVCHIND4_008190525..90956 [-], 432259156339  [UniProt] EexS
82ICEVCHIND4_008291011..91544 [-], 534259156342  [UniProt] transcriptional activator
83ICEVCHIND4_008391541..91840 [-], 300259156349  [UniProt] SetD
84ICEVCHIND4_008491837..92385 [-], 549259156338  [UniProt] lytic transglycosylase, catalytic
85ICEVCHIND4_008592372..93034 [-], 663259156362  [UniProt] conserved hypothetical protein
86ICEVCHIND4_008693021..93890 [-], 870259156356  [UniProt] conserved hypothetical protein
87ICEVCHIND4_008793946..94197 [-], 252259156322  [UniProt] SetQ
88ICEVCHIND4_008894315..94962 [+], 648259156299  [UniProt] HTH-type transcriptional regulator for conjugative element R391
89ICEVCHIND4_008995219..95326 [+], 108259156351  [UniProt] peptide termination factor
 
integrase Gene may contribute to site-specific recombination
conjugation Gene may play role in conjugative transfer
regulation Gene may play role in regulation of transfer

ElementNo. of sequencesDownload
Nucleotide sequences1Fasta
Proteins89Fasta
(1) Wozniak RA; Fouts DE; Spagnoletti M; Colombo MM; Ceccarelli D; Garriss G; Dery C; Burrus V; Waldor MK (2009). Comparative ICE genomics: insights into the evolution of the SXT/R391 family of ICEs. PLoS Genet. 5(12):e1000786. [PudMed:20041216] in_silico
(2) Marrero J; Waldor MK (2007). The SXT/R391 family of integrative conjugative elements is composed of two exclusion groups. J Bacteriol. 189(8):3302-5. [PudMed:17307849] experimental
 
experimental experimental literature
in_silico in silico analysis literature