ICEberg
ICEberg ID23
NameICEVchMex1
FamilySXT/R391
OrganismVibrio cholerae non O1-O139 Mex1
Size (bp)83194
GC content [Genome] (%)46.7
Insertion siteprfC
FunctionResistant to ampicillin; restriction modification system
Species that ICE can be transferred to-
Nucleotide SequenceGQ463143 (complete ICE sequence in this GenBank file)
Replicon-
Coordinates1..83194
Link to view genome context of this ICE in the genome browser
experimental This is a ICE derived from experimental literature.
Complete gene list of ICEVchMex1 form GQ463143
#GeneCoordinates [+/-], size (bp)Protein GI Product *
1ICEVCHMEX1_0001872..1192 [+], 321259156517  [UniProt] transcriptional regulator, XRE familyTA
2ICEVCHMEX1_00021185..2399 [+], 1215259156518  [UniProt] HipA domain proteinTA
3ICEVCHMEX1_00032616..2810 [+], 195259156504  [UniProt] conserved domain protein
4ICEVCHMEX1_00042827..4068 [-], 1242259156512  [UniProt] integrase
5ICEVCHMEX1_00054070..4339 [-], 270259156544  [UniProt] conserved hypothetical protein
6ICEVCHMEX1_00064342..5316 [-], 975259156533  [UniProt] conserved hypothetical protein
7ICEVCHMEX1_00075412..5579 [+], 168259156516  [UniProt] hypothetical protein
8ICEVCHMEX1_00085781..6224 [+], 444259156525  [UniProt] conserved hypothetical protein
9ICEVCHMEX1_00096235..7554 [-], 1320259156502  [UniProt] protein UmuC
10ICEVCHMEX1_00107511..7960 [-], 450259156489  [UniProt] protein UmuD
11ICEVCHMEX1_00118600..9505 [+], 906259156499  [UniProt] exonuclease, RNase T and DNA polymerase III
12ICEVCHMEX1_00129719..10018 [+], 300259156491  [UniProt] conserved hypothetical protein
13ICEVCHMEX1_001310336..11259 [+], 924259156494  [UniProt] conserved hypothetical protein
14hsdM11329..12903 [+], 1575259156470  [UniProt] type I restriction-modification system, M subunit
15ICEVCHMEX1_001512900..14222 [+], 1323259156528  [UniProt] specificity subunit
16ICEVCHMEX1_001614311..15312 [+], 1002259156498  [UniProt] filamentation induced by cAMP protein Fic
17ICEVCHMEX1_001715376..18489 [+], 3114259156503  [UniProt] type I site-specific deoxyribonuclease, R subunit
18ICEVCHMEX1_002019499..21649 [+], 2151259156539  [UniProt] conjugative relaxase
19ICEVCHMEX1_002121698..23518 [+], 1821259156486  [UniProt] conjugative coupling factor
20ICEVCHMEX1_002223528..24088 [+], 561259156530  [UniProt] conserved hypothetical protein
21ICEVCHMEX1_002324075..24710 [+], 636259156526  [UniProt] putative conjugation coupling factor
22ICEVCHMEX1_002424848..25954 [+], 1107259156500  [UniProt] filamentation induced by cAMP protein Fic
23traL26144..26425 [+], 282259156473  [UniProt] type IV conjugative transfer system protein TraL
24ICEVCHMEX1_002626422..27048 [+], 627259156546  [UniProt] sex pilus assembly
25ICEVCHMEX1_002727032..27931 [+], 900259156529  [UniProt] TraK
26ICEVCHMEX1_002827931..29220 [+], 1290259156519  [UniProt] sex pilus assembly
27ICEVCHMEX1_002929295..29867 [+], 573259156510  [UniProt] sex pilus assembly
28ICEVCHMEX1_003029864..30250 [+], 387259156485  [UniProt] TraA
29ICEVCHMEX1_003130291..30797 [-], 507259156476  [UniProt] acetyltransferase, gnat family
30ICEVCHMEX1_003230788..31054 [-], 267259156481  [UniProt] conserved hypothetical protein
31ICEVCHMEX1_003331209..31634 [-], 426259156475  [UniProt] conserved hypothetical protein
32ICEVCHMEX1_003532567..33361 [+], 795259156531  [UniProt] aminoglycoside 3'-phosphotransferase
33ICEVCHMEX1_003633571..34263 [+], 693259156521  [UniProt] DsbC
34traC34264..36663 [+], 2400259156478  [UniProt] type-IV secretion system protein TraC
35ICEVCHMEX1_003836656..37003 [+], 348259156508  [UniProt] conserved hypothetical protein
36ICEVCHMEX1_003936987..37499 [+], 513259156495  [UniProt] conjugation signal peptidase
37ICEVCHMEX1_004138618..39646 [+], 1029259156477  [UniProt] sex pilus assembly
38ICEVCHMEX1_004239649..43341 [+], 3693259156469  [UniProt] mating pair stabilization
39ICEVCHMEX1_004443354..43497 [+], 144259156545  [UniProt] hypothetical protein
40ICEVCHMEX1_004343483..45159 [-], 1677259156483  [UniProt] UvrD/REP helicase
41ICEVCHMEX1_004545156..47081 [-], 1926259156490  [UniProt] ATP-dependent endonuclease of the OLD family
42ICEVCHMEX1_004647159..49537 [-], 2379259156488  [UniProt] peptidase, S8A
43ICEVCHMEX1_004749553..50524 [-], 972259156540  [UniProt] ATPase, AAA family
44ICEVCHMEX1_004850635..50814 [-], 180259156493  [UniProt] conserved hypothetical protein
45ICEVCHMEX1_004950948..51550 [-], 603259156515  [UniProt] conserved hypothetical protein
46ICEVCHMEX1_005051918..52244 [+], 327259156474  [UniProt] conserved hypothetical protein
47ICEVCHMEX1_005152260..52679 [+], 420259156471  [UniProt] single-strand binding protein familyVF
48ICEVCHMEX1_005252759..53577 [+], 819259156487  [UniProt] phage recombination protein Bet
49ICEVCHMEX1_005353659..53802 [+], 144259156482  [UniProt] hypothetical protein
50ICEVCHMEX1_005453864..54880 [+], 1017259156534  [UniProt] YqaJ viral recombinase family
51ICEVCHMEX1_005555090..56049 [+], 960259156535  [UniProt] ATPase associated with various cellular activities, AAA_5
52ICEVCHMEX1_005656049..56816 [+], 768259156522  [UniProt] conserved hypothetical protein
53ICEVCHMEX1_005756915..57868 [+], 954259156541  [UniProt] conserved hypothetical protein
54ICEVCHMEX1_005857930..58370 [+], 441259156509  [UniProt] conserved hypothetical protein
55ICEVCHMEX1_005958440..60095 [+], 1656259156497  [UniProt] von Willebrand factor, type A
56radC60178..60675 [+], 498259156536  [UniProt] DNA repair protein RadCVF
57ICEVCHMEX1_006160675..61016 [+], 342259156542  [UniProt] conserved hypothetical protein
58ICEVCHMEX1_006261108..62181 [+], 1074259156507  [UniProt] phage P4 alpha, zinc-binding domain protein
59ICEVCHMEX1_006362271..62978 [+], 708259156484  [UniProt] conserved hypothetical protein
60ICEVCHMEX1_006463001..63126 [+], 126259156537  [UniProt] hypothetical protein
61ICEVCHMEX1_006563095..63847 [+], 753259156523  [UniProt] conserved hypothetical protein
62ICEVCHMEX1_006663902..64438 [-], 537259156511  [UniProt] conserved hypothetical protein
63ICEVCHMEX1_006764799..66070 [+], 1272259156472  [UniProt] pas/pac/ggdef-domain containing protein
64ICEVCHMEX1_006866244..66669 [+], 426259156496  [UniProt] integrase, catalytic region
65ICEVCHMEX1_006966830..67759 [-], 930259156480  [UniProt] response regulator receiver protein
66ICEVCHMEX1_007067765..71571 [-], 3807259156506  [UniProt] multi-sensor hybrid histidine kinaseVF
67ICEVCHMEX1_007171572..71688 [-], 117259156527  [UniProt] hypothetical protein
68ICEVCHMEX1_007272019..72165 [+], 147259156501  [UniProt] hypothetical protein
69ICEVCHMEX1_007372311..73255 [+], 945259156514  [UniProt] conserved hypothetical protein
70ICEVCHMEX1_007473258..74646 [+], 1389259156492  [UniProt] sex pilus assembly
71ICEVCHMEX1_007574650..78219 [+], 3570259156513  [UniProt] sex pilus assembly
72ICEVCHMEX1_007678252..78683 [-], 432259156479  [UniProt] EexR3
73ICEVCHMEX1_007778741..79274 [-], 534259156524  [UniProt] transcriptional activator
74ICEVCHMEX1_007879271..79570 [-], 300259156543  [UniProt] SetD
75ICEVCHMEX1_008380759..81628 [-], 870259156520  [UniProt] conserved hypothetical protein
76ICEVCHMEX1_008481684..81935 [-], 252259156538  [UniProt] SetQ
77ICEVCHMEX1_008582053..82700 [+], 648259156532  [UniProt] HTH-type transcriptional regulator for conjugative element R391
78ICEVCHMEX1_008682957..83194 [+], 238259156505  [UniProt] peptide termination factor
 
integrase Gene may contribute to site-specific recombination
conjugation Gene may play role in conjugative transfer
regulation Gene may play role in regulation of transfer

ElementNo. of sequencesDownload
Nucleotide sequences1Fasta
Proteins78Fasta
(1) Wozniak RA; Fouts DE; Spagnoletti M; Colombo MM; Ceccarelli D; Garriss G; Dery C; Burrus V; Waldor MK (2009). Comparative ICE genomics: insights into the evolution of the SXT/R391 family of ICEs. PLoS Genet. 5(12):e1000786. [PudMed:20041216] in_silico
(2) Bordeleau E; Brouillette E; Robichaud N; Burrus V (2010). Beyond antibiotic resistance: integrating conjugative elements of the SXT/R391 family that encode novel diguanylate cyclases participate to c-di-GMP signalling in Vibrio cholerae. Environ Microbiol. 12(2):510-23. [PudMed:19888998] experimental
(3) Marrero J; Waldor MK (2007). The SXT/R391 family of integrative conjugative elements is composed of two exclusion groups. J Bacteriol. 189(8):3302-5. [PudMed:17307849] experimental
(4) Burrus V; Quezada-Calvillo R; Marrero J; Waldor MK (2006). SXT-related integrating conjugative element in New World Vibrio cholerae. Appl Environ Microbiol. 72(4):3054-7. [PudMed:16598018] experimental
 
experimental experimental literature
in_silico in silico analysis literature