ICEberg
ICEberg ID408
NameICESpy10394-1
FamilyTn1207.3
OrganismStreptococcus pyogenes MGAS10394
Size (bp)52492
GC content [Genome] (%)39.2 [38]
Insertion site-
Functionmacrolide resistance
Species that ICE can be transferred to-
Nucleotide SequenceCP000003 (complete ICE sequence in this genome)
Replicon chromosome (1899877 bp, Project:12469) [NC_006086]
Genome coordinates1119537..1172028
Link to view genome context of this ICE in the genome browser
in_silico This is a predicted ICE derivied from literature.
Complete gene list of ICESpy10394-1 form CP000003
#GeneCoordinates [+/-], size (bp)Protein GI Product *
1M6_Spy11161114619..1115839 [+], 122150903536 Hypothetical cytosolic protein
2M6_Spy11171115953..1116543 [-], 59150903537 Hypothetical protein
3M6_Spy11181116540..1116779 [-], 24050903538 Hypothetical protein
4M6_Spy11191116835..1116981 [-], 14750903539 Hypothetical protein
5M6_Spy11201117148..1117753 [-], 60650903540 Superoxide dismutase
6M6_Spy11211117850..1118890 [-], 104150903541 DNA polymerase III, delta subunit
7M6_Spy11221118971..1119552 [-], 58250903542 ComE operon protein 3
8M6_Spy11231119626..1120201 [-], 57650903543  [UniProt]  [KEGG]Hypothetical Protein
9M6_Spy11241120257..1121822 [-], 156650903544  [UniProt]  [KEGG]Site-specific recombinase
10M6_Spy11251121819..1123057 [-], 123950903545  [UniProt]  [KEGG]Site-specific recombinase
11M6_Spy11261123382..1124164 [-], 78350903546  [UniProt]  [KEGG]Phage-associated cell wall hydrolase
12M6_Spy11271124148..1126430 [-], 228350903547  [UniProt]  [KEGG]Phage structural protein
13M6_Spy11281126443..1129331 [-], 288950903548  [UniProt]  [KEGG]Phage endopeptidase
14M6_Spy11291129331..1130056 [-], 72650903549  [UniProt]  [KEGG]unknown phage protein
15M6_Spy11301130053..1133172 [-], 312050903550  [UniProt]  [KEGG]unknown phage protein
16M6_Spy11311133190..1133342 [-], 15350903551  [UniProt]  [KEGG]unknown phage protein
17M6_Spy11321133351..1133770 [-], 42050903552  [UniProt]  [KEGG]prophage pi2 protein 40
18M6_Spy11331133767..1134357 [-], 59150903553  [UniProt]  [KEGG]prophage pi2 protein 39
19M6_Spy11341134370..1134687 [-], 31850903554  [UniProt]  [KEGG]prophage pi2 protein 38
20M6_Spy11351134684..1135064 [-], 38150903555  [UniProt]  [KEGG]prophage pi2 protein 37
21M6_Spy11361135040..1135369 [-], 33050903556  [UniProt]  [KEGG]unknown phage protein
22M6_Spy11371135370..1135573 [-], 20450903557  [UniProt]  [KEGG]unknown phage protein
23M6_Spy11381135637..1136824 [-], 118850903558  [UniProt]  [KEGG]Phage Prohead Protease
24M6_Spy11391136840..1137526 [-], 68750903559  [UniProt]  [KEGG]ATP-dependent Clp protease proteolytic subunit
25M6_Spy11401137519..1138760 [-], 124250903560  [UniProt]  [KEGG]Portal protein
26M6_Spy11411138772..1140364 [-], 159350903561  [UniProt]  [KEGG]Terminase large subunit
27M6_Spy11421140366..1140842 [-], 47750903562  [UniProt]  [KEGG]Phage Terminase Small Subunit
28M6_Spy11431141730..1142998 [-], 126950903563  [UniProt]  [KEGG]DNA-cytosine methyltransferase
29M6_Spy11441142995..1144227 [-], 123350903564  [UniProt]  [KEGG]Chromosome partitioning protein
30M6_Spy11451144242..1144646 [-], 40550903565  [UniProt]  [KEGG]Zinc-finger protein
31M6_Spy11461144894..1145301 [-], 40850903566  [UniProt]  [KEGG]Phage endonuclease
32M6_Spy11471145261..1146322 [-], 106250903567  [UniProt]  [KEGG]S-adenosylmethionine synthetase
33M6_Spy11481147030..1147533 [-], 50450903568  [UniProt]  [KEGG]unknown phage protein
34M6_Spy11491147526..1148902 [-], 137750903569  [UniProt]  [KEGG]Phage-related DNA helicase
35M6_Spy11501148883..1149185 [-], 30350903570  [UniProt]  [KEGG]Phage-related protein
36M6_Spy11511149449..1151734 [-], 228650903571  [UniProt]  [KEGG]Phage DNA polymerase
37M6_Spy11521152121..1152444 [+], 32450903572  [UniProt]  [KEGG]unknown phage protein
38M6_Spy11531152413..1153558 [+], 114650903573  [UniProt]  [KEGG]unknown phage protein
39M6_Spy11541153539..1154111 [+], 57350903574  [UniProt]  [KEGG]unknown phage protein
40M6_Spy11551154346..1156301 [+], 195650903575  [UniProt]  [KEGG]phage-related DNA polymerase
41M6_Spy11561156340..1156909 [-], 57050903576  [UniProt]  [KEGG]Hypothetical Protein
42M6_Spy11571157255..1158409 [+], 115550903577  [UniProt]  [KEGG]Hypothetical Protein
43M6_Spy11581158431..1159711 [-], 128150903578  [UniProt]  [KEGG]Type II restriction-modification system restriction subunit
44M6_Spy11591159692..1161359 [-], 166850903579  [UniProt]  [KEGG]Type II restriction-modification system restriction subunit
45M6_Spy11601161392..1162618 [+], 122750903580  [UniProt]  [KEGG]Type II restriction-modification system methylation subunit
46M6_Spy11611162732..1163421 [+], 69050903581  [UniProt]  [KEGG]Phage transcriptional repressor
47M6_Spy11621163774..1165189 [+], 141650903582  [UniProt]  [KEGG]ImpB/MucB/SamB family protein
48M6_Spy11631165186..1165554 [+], 36950903583  [UniProt]  [KEGG]Hypothetical protein
49M6_Spy11641165541..1165840 [+], 30050903584  [UniProt]  [KEGG]Hypothetical Protein
50M6_Spy11651165958..1167421 [-], 146450903585  [UniProt]  [KEGG]Macrolide-specific ABC-type efflux carrier
51M6_Spy11661167541..1168758 [-], 121850903586  [UniProt]  [KEGG]Macrolide-efflux proteinAR
52M6_Spy11671169588..1170004 [-], 41750903587  [UniProt]  [KEGG]Hypothetical Protein
53M6_Spy11681170019..1171131 [-], 111350903588  [UniProt]  [KEGG]Site-specific recombinase
54M6_Spy11691171260..1171916 [-], 65750903589  [UniProt]  [KEGG]Hypothetical Protein
55M6_Spy11701172075..1172533 [-], 45950903590 Hypothetical Protein
56M6_Spy11711172789..1173256 [-], 46850903591 Site-specific recombinase
57M6_Spy11721173422..1173823 [-], 40250903592 Zinc-finger protein
 
flank Flanking regions
integrase Gene may contribute to site-specific recombination

ElementNo. of sequencesDownload
Nucleotide sequences1Fasta
Proteins47Fasta
(1) Banks DJ; Porcella SF; Barbian KD; Beres SB; Philips LE; Voyich JM; DeLeo FR; Martin JM; Somerville GA; Musser JM (2004). Progress toward characterization of the group A Streptococcus metagenome: complete genome sequence of a macrolide-resistant serotype M6 strain. J Infect Dis. 190(4):727-38. [PudMed:15272401]
(2) Banks DJ; Porcella SF; Barbian KD; Martin JM; Musser JM (2003). Structure and distribution of an unusual chimeric genetic element encoding macrolide resistance in phylogenetically diverse clones of group A Streptococcus. J Infect Dis. 188(12):1898-908. [PudMed:14673771] experimental
 
experimental experimental literature