ICEberg
ICEberg ID409
NameICESp1108
FamilyTn1806
OrganismStreptococcus pyogenes C1
Size (bp)45456
GC content [Genome] (%)31.1
Insertion site3' end of the rum gene
Functionspectinomycin, erythromycin, tetronasin resistance
Species that ICE can be transferred to-
Nucleotide SequenceFR691054 (complete ICE sequence in this GenBank file)
Replicon-
Coordinates1694..47149
Link to view genome context of this ICE in the genome browser
experimental This is a ICE derived from experimental literature.
Complete gene list of ICESp1108 form FR691054
#GeneCoordinates [+/-], size (bp)Protein GI Product *
1rum332..1720 [+], 1389338795738 23S rRNA m(5)U 1939 methyltransferase
2ORF11951..2586 [+], 636338795739 replication initiator protein
3ORF22583..3410 [+], 828338795740 DNA replication protein
4ORF33403..3888 [+], 486338795741 hypothetical protein
5ORF43885..4619 [+], 735338795742 phage antirepressor protein
6ORF54612..6408 [+], 1797338795743 TraG/TraD/VirD4 bacterial conjugation protein
7ORF66427..6702 [+], 276338795744 hypothetical protein
8ORF76814..7182 [+], 369338795745 hypothetical protein
9ORF87529..7822 [+], 294338795746 hypothetical protein
10ORF98045..8356 [+], 312338795747 hypothetical protein
11ORF108358..8573 [+], 216338795748 hypothetical protein
12ORF118584..9447 [+], 864338795749 hypothetical protein
13ORF129457..9747 [+], 291338795750 hypothetical protein
14ORF139749..10159 [+], 411338795751 bacitracin resistance protein
15ORF1410050..12470 [+], 2421338795752 type IV secretory pathway protein VirB4
16ORF1512478..15057 [+], 2580338795753 NlpC/P60 family proteinVF
17ORF1615298..16881 [+], 1584338795754 amine oxidase
18ORF1716896..17756 [+], 861338795755 hypothetical protein
19ORF1818053..18256 [+], 204338795756 hypothetical protein
20ORF1918492..19232 [+], 741338795757 hypothetical protein
21ORF2019354..21087 [+], 1734338795758 DNA topoisomerase IA
22ORF2121080..22045 [+], 966338795759 C-5 cytosine specific DNA methylase
23ORF2222032..29675 [+], 7644338795760 superfamily II DNA/RNA helicase
24ORF2329719..30375 [+], 657338795761  [UniProt] hypothetical protein
25ORF2430927..31559 [+], 633338795762  [UniProt] transcriptional regulator, TetR familyVF
26ORF2531644..32525 [+], 882338795763  [UniProt] tetronasin resistance ATP-binding protein
27ORF2632458..34164 [+], 1707338795764  [UniProt] tetronasin resistance transmembrane protein
28ORF2734745..34951 [-], 207338795765  [UniProt] hypothetical protein
29erm(TR)34898..35629 [+], 732338795766  [UniProt] erythromycin resistance methylaseAR
30ORF2935846..36370 [+], 525338795767  [UniProt] spectinomycin phosphotransferase
31ORF3036416..36535 [+], 120338795768  [UniProt] hypothetical protein
32ORF3137228..38451 [+], 1224338795769  [UniProt] transposase IS116/IS110/IS902 family protein
33ORF3238857..40188 [-], 1332338795770  [UniProt] relaxase/mobilization protein
34ORF3340190..40648 [-], 459338795771  [UniProt] hypothetical protein
35ORF3440717..41811 [-], 1095338795772  [UniProt] RhuMVF
36ORF3541792..42274 [-], 483338795773 cation transporter family protein
37ORF3642283..42831 [-], 549338795774 Zn-dependent peptidaseTA
38ORF3742840..43241 [-], 402338795775 trascriptional regulator Cro/CI family proteinTA
39ORF3843376..43951 [+], 576338795776 hypothetical protein
40ORF3944221..44631 [+], 411338795777 RNA polymerase sigma-70 region 4
41ORF4045362..47149 [+], 1788338795778 putative recombinase
42pnp47452..47850 [+], 399338795779 phosphorylase
 
flank Flanking regions
integrase Gene may contribute to site-specific recombination
conjugation Gene may play role in conjugative transfer

ElementNo. of sequencesDownload
Nucleotide sequences1Fasta
Proteins40Fasta
(1) Brenciani A; Tiberi E; Bacciaglia A; Petrelli D; Varaldo PE; Giovanetti E (2011). Two distinct genetic elements are responsible for erm(TR)-mediated erythromycin resistance in tetracycline-susceptible and tetracycline-resistant strains of Streptococcus pyogenes. Antimicrob Agents Chemother. 55(5):2106-12. [PudMed:21343455] experimental
 
experimental experimental literature