ICEberg ID60
OrganismHaemophilus influenzae 1056
Size (bp)59393
GC content [Genome] (%)39.1
Insertion sitetRNA-Leu
FunctionTetracycline resistance
Species that ICE can be transferred toHaemophilus influenzae; Haemophilus parainfluenzae
Nucleotide SequenceAJ627386 (complete ICE sequence in this GenBank file)
Link to view genome context of this ICE in the genome browser
experimental This is a ICE derived from experimental literature.
Complete gene list of ICEHin1056 form AJ627386
#GeneCoordinates [+/-], size (bp)Protein GI Product *
1p1056.01141..977 [+], 83751507260  [UniProt] putative chromosome partitioning related protein
2p1056.02979..2334 [+], 135651507261  [UniProt] replicative DNA helicase
3p1056.032327..4015 [+], 168951507262  [UniProt] conserved hypothetical protein
4p1056.044015..4566 [+], 55251507263  [UniProt] conserved hypothetical protein
5p1056.054716..5939 [+], 122451507264  [UniProt] conserved hypothetical protein
6p1056.066164..6919 [+], 75651507265  [UniProt] conserved hypothetical protein
7inrR6919..7407 [+], 48951507266  [UniProt] conserved hypothetical protein
8p1056.087654..8076 [+], 42351507267  [UniProt] single-strand binding proteinVF
9p1056.098100..8621 [+], 52251507268  [UniProt] putative lipoprotein
10p1056.10c8837..9394 [-], 55851507269  [UniProt] hypothetical protein
11p1056.119485..11530 [+], 204651507270  [UniProt] DNA topoisomerase III
12p1056.1212415..12843 [+], 42951507271  [UniProt] conserved hypothetical protein
13p1056.1312919..13599 [+], 68151507272  [UniProt] hypothetical protein
14p1056.1413738..14208 [+], 47151507273  [UniProt] putative DNA repair-like proteinVF
15p1056.1514301..14780 [+], 48051507274  [UniProt] hypothetical protein
16p1056.1614720..15838 [+], 111951507275  [UniProt] transposase for Tn10VF
17p1056.17c15964..16896 [-], 93351507276  [UniProt] transposase for insertion sequence element IS5
18cat17570..18211 [-], 64251507277  [UniProt] chloramphenicol acetyltransferase IIAR VF
19p1056.19c18374..19321 [-], 94851507278  [UniProt] putative transposase, IS30 family
20p1056.2019653..20438 [+], 78651507279  [UniProt] putative transposase for insertion sequence element IS5
21p1056.2120822..21142 [+], 32151507280  [UniProt] putative monooxygenase
22p1056.2221024..21521 [+], 49851507281  [UniProt] conserved hypothetical proteinVF
23p1056.2321529..22215 [+], 68751507282  [UniProt] Putative transcriptional regulatorVF
24p1056.24c22193..22815 [-], 623pseudogene Tetracycline repressor protein class B from transposon Tn10 (pseudogene)
25tetA22897..24102 [+], 120651507283  [UniProt] putative tetracycline resistance proteinAR VF
26tetC24215..24808 [-], 59451507284  [UniProt] putative transcriptional regulatorVF
27tetD24896..25312 [+], 41751507285  [UniProt] putative regulatory proteinVF
28tnp25322..26530 [-], 120951507286  [UniProt] putative transposaseVF
29p1056.2926582..26931 [+], 350pseudogene conserved hypothetical protein (pseudogene)
30p1056.3026989..27753 [+], 76551507287  [UniProt] conserved hypothetical protein
31pilL27852..28481 [+], 63051507288  [UniProt] putative lipoprotein precursor
32p1056.3228485..29225 [+], 74151507289  [UniProt] putative exported protein precursor
33p1056.3329204..29962 [+], 75951507290  [UniProt] putative exported protein precursor
34p1056.3429978..30484 [+], 50751507291  [UniProt] putative exported protein precursor
35p1056.3530481..32730 [+], 225051507292  [UniProt] conserved hypothetical protein
36p1056.3632741..33049 [+], 30951507293  [UniProt] conserved hypothetical protein
37p1056.3733049..33735 [+], 68751507294  [UniProt] Putative membrane protein
38p1056.3833866..34216 [+], 35151507295  [UniProt] Putative exported protein precursor
39p1056.3934485..34886 [+], 40251507296  [UniProt] putative membrane protein
40p1056.4034906..35277 [+], 37251507297  [UniProt] putative membrane protein
41p1056.4135289..35918 [+], 63051507298  [UniProt] putative exported protein precursor
42p1056.4235937..36806 [+], 87051507299  [UniProt] conserved hypothetical protein
43p1056.4336817..38217 [+], 140151507300  [UniProt] putative exported protein precursor
44p1056.4438227..38634 [+], 40851507301  [UniProt] putative lipoprotein precursor
45p1056.4538650..41520 [+], 287151507302  [UniProt] conserved hypothetical protein
46p1056.4641528..41935 [+], 40851507303  [UniProt] conserved hypothetical protein
47p1056.4741945..42268 [+], 32451507304  [UniProt] hypothetical membrane protein
48p1056.4842277..43770 [+], 149451507305  [UniProt] Putative membrane protein
49p1056.49c43826..44155 [-], 33051507306  [UniProt] hypothetical membrane protein
50p1056.50c44575..44982 [-], 40851507307  [UniProt] hypothetical exported protein
51p1056.51c44998..46998 [-], 200151507308  [UniProt] putative exported protein precursor
52p1056.52c47013..47939 [-], 92751507309  [UniProt] putative exported protein
53p1056.53c47951..48388 [-], 43851507310  [UniProt] conserved hypothetical protein
54p1056.5448763..49125 [+], 36351507311  [UniProt] hypothetical membrane protein
55p1056.5549210..49443 [+], 23451507312  [UniProt] conserved hypothetical protein
56p1056.5649985..50890 [+], 90651507313  [UniProt] putative antirestriction protein
57blaTEM1D50985..51845 [-], 86151507314  [UniProt] beta-lactamase TEM precursorAR
58p1056.58c52028..52585 [-], 55851507315  [UniProt] transposon Tn3 resolvase
59p1056.5952884..53201 [+], 31851507316  [UniProt] hypothetical protein
60p1056.6053491..54189 [+], 69951507317  [UniProt] putative DNA-binding protein
61p1056.61c54706..55260 [-], 55551507318  [UniProt] hypothetical protein
62p1056.6255497..57404 [+], 190851507319  [UniProt] conserved hypothetical protein
63p1056.6357495..58307 [+], 81351507320  [UniProt] Putative site-specific recombinase
64p1056.64c58302..59078 [-], 77751507321  [UniProt] conserved phage-related hypothetical protein
integrase Gene may contribute to site-specific recombination
conjugation Gene may play role in conjugative transfer

ElementNo. of sequencesDownload
Nucleotide sequences1Fasta
(1) Seth-Smith HM; Fookes MC; Okoro CK; Baker S; Harris SR; Scott P; Pickard D; Quail MA; Churcher C; Sanders M; Harmse J; Dougan G; Parkhill J; Thomson NR (2012). Structure, diversity, and mobility of the Salmonella pathogenicity island 7 family of integrative and conjugative elements within Enterobacteriaceae. J Bacteriol. 194(6):1494-504. [PudMed:22247511] in_silico
(2) Saha SK; Darmstadt GL; Baqui AH; Islam N; Qazi S; Islam M; El Arifeen S; Santosham M; Black RE; Crook DW (2008). Direct detection of the multidrug resistance genome of Haemophilus influenzae in cerebrospinal fluid of children: implications for treatment of meningitis. Pediatr Infect Dis J. 27(1):49-53. [PudMed:18162938] experimental
(3) Juhas M; Power PM; Harding RM; Ferguson DJ; Dimopoulou ID; Elamin AR; Mohd-Zain Z; Hood DW; Adegbola R; Erwin A; Smith A; Munson RS; Harrison A; Mansfield L; Bentley S; Crook DW (2007). Sequence and functional analyses of Haemophilus spp. genomic islands. Genome Biol. 8(11):R237. [PudMed:17996041] in_silico
(4) Dimopoulou ID; Kartali SI; Harding RM; Peto TE; Crook DW (2007). Diversity of antibiotic resistance integrative and conjugative elements among haemophili. J Med Microbiol. 56(Pt 6):838-46. [PudMed:17510272] experimental
(5) Mohd-Zain Z; Turner SL; Cerdeno-Tarraga AM; Lilley AK; Inzana TJ; Duncan AJ; Harding RM; Hood DW; Peto TE; Crook DW (2004). Transferable antibiotic resistance elements in Haemophilus influenzae share a common evolutionary origin with a diverse family of syntenic genomic islands. J Bacteriol. 186(23):8114-22. [PudMed:15547285] experimental
experimental experimental literature
in_silico in silico analysis literature