ICEberg ID78
OrganismStreptococcus thermophilus CNRZ368
Size (bp)35870
GC content [Genome] (%)35
Insertion sitefda
FunctionType II Restriction-Modification System
Species that ICE can be transferred to-
Nucleotide SequenceAJ278471 (complete ICE sequence in this GenBank file)
Link to view genome context of this ICE in the genome browser
experimental This is a ICE derived from experimental literature.
Complete gene list of ICESt1 form AJ278471
#GeneCoordinates [+/-], size (bp)Protein GI Product *
1transposase249..1241 [+], 993pseudogene -
2-1752..2936 [-], 118515485428  [UniProt] putative Abi-alpha protein
3gst3491..4708 [+], 121815485429  [UniProt] putative glutamate/aspartate-proton symport protein
4-4728..5657 [+], 93015485430  [UniProt] putative carboxylate-amine/thiol ligase
5-5841..7016 [-], 117615485431  [UniProt] putative transposase
6-9382..10515 [-], 113415485432  [UniProt] putative ATP/GTP-binding protein
7-10516..11286 [-], 77115485433  [UniProt] hypothetical protein
8-11316..11339 [-], 2415485434 ORFV1 protein
9-11774..12199 [+], 42615485435  [UniProt] hypothetical protein
10-12382..14103 [-], 172215485436  [UniProt] putative ATP/GTP-binding protein
11-14462..14767 [+], 30615485437  [UniProt] hypothetical protein
12sth368IR14837..16312 [-], 147615485438  [UniProt] R.Sth368I endonuclease
13sth368IM16428..17693 [+], 126615485439  [UniProt] M.Sth368I methyltransferase
14-17725..18024 [-], 30015485440  [UniProt] hypothetical protein
15arp118017..18715 [-], 69915485441  [UniProt] hypothetical transcriptional regulator
16-18724..19581 [-], 85815485442  [UniProt] hypothetical protein
17-19679..20995 [-], 131715485443  [UniProt] hypothetical protein
18arp220985..21320 [-], 33615485444  [UniProt] hypothetical transcriptional regulator
19-22183..22479 [+], 29715485445  [UniProt] hypothetical protein
20-22501..22962 [+], 46215485446  [UniProt] hypothetical protein
21-22976..24664 [+], 168915485447  [UniProt] putative transfer protein
22-24872..26104 [+], 123315485448  [UniProt] putative transfer protein
23-26119..26349 [+], 23115485449  [UniProt] hypothetical protein
24-26354..26911 [+], 55815485450  [UniProt] hypothetical protein
25ORFH26414..26911 [+], 49815485451  [UniProt] hypothetical protein
26-26923..27918 [+], 99615485452  [UniProt] putative transfer protein
27-27928..28152 [+], 22515485453  [UniProt] hypothetical protein
28ORFE28155..28532 [+], 37815485454  [UniProt] putative transfer protein
29-28578..31082 [+], 250515485455  [UniProt] putative ATP/GTP-binding protein
30-31094..32974 [+], 188115485456  [UniProt] putative transmembrane protein
31-32976..33200 [+], 22515485457  [UniProt] hypothetical protein
32-33226..34338 [+], 111315485458  [UniProt] putative transfer protein
33xis34352..34600 [+], 24915485459  [UniProt] excisionase
34int34600..35946 [+], 134715485460  [UniProt] integrase
35fda36030..36272 [-], 24315485461 putative fructose-1,6-biphosphate aldolase
flank Flanking regions
integrase Gene may contribute to site-specific recombination
conjugation Gene may play role in conjugative transfer

ElementNo. of sequencesDownload
Nucleotide sequences1Fasta
(1) Carraro N; Libante V; Morel C; Decaris B; Charron-Bourgoin F; Leblond P; Guedon G (2011). Differential regulation of two closely related integrative and conjugative elements from Streptococcus thermophilus. BMC Microbiol. 0.623611111. [PudMed:22024428] experimental
(2) Bellanger X; Roberts AP; Morel C; Choulet F; Pavlovic G; Mullany P; Decaris B; Guedon G (2009). Conjugative transfer of the integrative conjugative elements ICESt1 and ICESt3 from Streptococcus thermophilus. J Bacteriol. 191(8):2764-75. [PudMed:19181800] experimental
(3) Bellanger X; Morel C; Decaris B; Guedon G (2008). Regulation of excision of integrative and potentially conjugative elements from Streptococcus thermophilus: role of the arp1 repressor. J Mol Microbiol Biotechnol. 14(1-3):16-21. [PudMed:17957106] experimental
(4) Bellanger X; Morel C; Decaris B; Guedon G (2007). Derepression of excision of integrative and potentially conjugative elements from Streptococcus thermophilus by DNA damage response: implication of a cI-related repressor. J Bacteriol. 189(4):1478-81. [PudMed:17114247] experimental
(5) Pavlovic G; Burrus V; Gintz B; Decaris B; Guedon G (2004). Evolution of genomic islands by deletion and tandem accretion by site-specific recombination: ICESt1-related elements from Streptococcus thermophilus. Microbiology. 150(Pt 4):759-74. [PudMed:15073287] experimental
(6) Burrus V; Pavlovic G; Decaris B; Guedon G (2002). The ICESt1 element of Streptococcus thermophilus belongs to a large family of integrative and conjugative elements that exchange modules and change their specificity of integration. Plasmid. 48(2):77-97. [PudMed:12383726] experimental in_silico
(7) Burrus V; Bontemps C; Decaris B; Guedon G (2001). Characterization of a novel type II restriction-modification system, Sth368I, encoded by the integrative element ICESt1 of Streptococcus thermophilus CNRZ368. Appl Environ Microbiol. 67(4):1522-8. [PudMed:11282600] experimental
(8) Burrus V; Roussel Y; Decaris B; Guedon G (2000). Characterization of a novel integrative element, ICESt1, in the lactic acid bacterium Streptococcus thermophilus. Appl Environ Microbiol. 66(4):1749-53. [PudMed:10742276] experimental
experimental experimental literature
in_silico in silico analysis literature