SecReT4
T4SS ID34
StrainHelicobacter pylori B8
Repliconchromosome [Browse all T4SS(s) in this replicon]
AccessionNC_014256
Location671072..701978
NameCag
Functioneffector translocation
ClassificationType IVA; Type P
sequence This T4SS has been mentioned in a genome sequencing report.

T4SS components
ComponentCagCCagDCagECagFCagGCagHCagICagLCagN
Number111111111
ComponentCagMCagTCagUCagVCagWCagXCagYCagZCagalpha
Number111111111
ComponentCagbetaCaggammaCagdelta
Number111

The information of T4SS components from NC_014256
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#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductComponent
1HPB8_691 (nudT14)666318..666956 [+], 639298736186UDP-sugar diphosphatase 
2HPB8_692666967..668022 [+], 1056298736187plasminogen-binding protein PgbA 
3HPB8_693 (glcD1)668024..669403 [+], 1380298736188FAD linked oxidase-like protein 
4HPB8_694 (dapB)669425..670189 [+], 765298736189Dihydrodipicolinate reductase 
5HPB8_695670413..670523 [-], 111298736190hypothetical protein 
6HPB8_696 (cagB)670637..670864 [+], 228298736191cag pathogenicity island protein B 
7HPB8_697 (cagC)671072..671356 [+], 285298736192cag pathogenicity island protein C  CagC
8HPB8_698 (cagD)671340..671984 [+], 645298736193cag pathogenicity island protein D  CagD
9HPB8_699 (cagE)671999..674944 [+], 2946298736194cag pathogenicity island protein E  CagE
10HPB8_700 (cagF)674946..675752 [+], 807298736195cag pathogenicity island protein F  CagF
11HPB8_701 (cagG)675807..676235 [+], 429298736196cag pathogenicity island protein G  CagG
12HPB8_702 (cagH)676237..677349 [+], 1113298736197cag pathogenicity island protein H  CagH
13HPB8_703 (cagI)677360..678505 [+], 1146298736198cag pathogenicity island protein I  CagI
14HPB8_704 (cagL)678502..679215 [+], 714298736199cag pathogenicity island protein L  CagL
15HPB8_705 (cagN)679297..680223 [-], 927298736200cag pathogenicity island protein N  CagN
16HPB8_706 (cagM)680232..681362 [-], 1131298736201cag pathogenicity island protein M  CagM
17HPB8_707681666..681782 [-], 117298736202hypothetical protein 
18HPB8_708682552..682854 [-], 303298736203hypothetical protein 
19HPB8_709 (cagQ)682562..682942 [+], 381298736204cag pathogenicity island protein Q 
20HPB8_710 (cagS)683384..683983 [+], 600298736205cag pathogenicity island protein S 
21HPB8_711 (cagT)684180..685022 [-], 843298736206cag pathogenicity island protein T  CagT
22HPB8_712 (cagU)685035..685685 [-], 651298736207cag pathogenicity island protein U  CagU
23HPB8_713 (cagV)686072..686830 [+], 759298736208cag pathogenicity island protein V  CagV
24HPB8_714 (cagW)686835..688433 [+], 1599298736209cag pathogenicity island protein W  CagW
25HPB8_715 (cagX)688486..690054 [+], 1569298736210cag pathogenicity island protein X  CagX
26HPB8_716 (cagY)690069..695534 [+], 5466298736211cag pathogenicity island protein Y  CagY
27HPB8_717 (cagZ)695683..696282 [+], 600298736212cag pathogenicity island protein Z  CagZ
28HPB8_718 (virB11-4)696287..697279 [+], 993298736213cag pathogenicity island protein alpha  Cagalpha
29HPB8_719 (cag5)697288..699534 [+], 2247298736214cag pathogenicity island protein beta  Cagbeta
30HPB8_720699579..699698 [-], 120298736215hypothetical protein 
31HPB8_721699618..699893 [+], 276298736216hypothetical protein 
32HPB8_722 (cag4)700014..700523 [-], 510298736217cag pathogenicity island protein gamma  Caggamma
33HPB8_723 (cag3)700533..701978 [-], 1446298736218cag pathogenicity island protein delta  Cagdelta
34HPB8_724 (cag2)701971..702675 [-], 705298736219cag pathogenicity island protein epsilon 
35HPB8_725 (cag1)702739..703086 [-], 348298736220cag pathogenicity island protein zeta 
36HPB8_726703259..704110 [+], 852298736221chitin synthase regulatory factor 3 
37HPB8_727704147..704326 [+], 180298736222hypothetical protein 
38HPB8_728 (glnA)704340..705785 [-], 1446298736223glutamine synthetase 
 
flank Genes in the 5-Kb flanking regions if available, or non-essential genes in the T4SS gene cluster if any.

Download FASTA format files
Proteins        Genes

Effectors
CagA; Peptidoglycan

The information of protein effectors
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  *
1HPB8_741 (cagA)716816..720370 [+], 3555298736236cytotoxin-associated protein A  CagA

Download FASTA format files
Proteins        Genes
(1) Farnbacher M; Jahns T; Willrodt D; Daniel R; Haas R; Goesmann A; Kurtz S; Rieder G (2010). Sequencing, annotation, and comparative genome analysis of the gerbil-adapted Helicobacter pylori strain B8. BMC Genomics. 11:335. [PudMed:20507619] in_silico
 
in_silico This literature contains bioinformatics investigation