SecReT4
T4SS ID36
StrainHelicobacter pylori Shi470
Repliconchromosome [Browse all T4SS(s) in this replicon]
AccessionNC_010698
Location808395..844300
NameCag
Functioneffector translocation
ClassificationType IVA; Type P
sequence This T4SS has been mentioned in a genome sequencing report.

T4SS components
ComponentCagCCagDCagECagFCagGCagHCagICagLCagN
Number211111111
ComponentCagMCagTCagUCagVCagWCagXCagYCagZCagalpha
Number111111111
ComponentCagbetaCaggammaCagdelta
Number111

The information of T4SS components from NC_010698
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#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductComponent
1HPSH_04145804109..807594 [-], 3486188527607cag pathogenicity island protein CagA 
2HPSH_04150808001..808228 [+], 228188527608cag pathogenicity island protein CagB 
3HPSH_04155808395..808742 [+], 348188527609cag pathogenicity island protein CagC  CagC
4HPSH_04160808744..809367 [+], 624188527610cag pathogenicity island protein CagD  CagD
5HPSH_04165809382..812327 [+], 2946188527611cag pathogenicity island protein CagE  CagE
6HPSH_04170812329..813135 [+], 807188527612cag pathogenicity island protein CagF  CagF
7HPSH_04175813190..813621 [+], 432188527613cag pathogenicity island protein CagG  CagG
8HPSH_04180813607..813804 [-], 198188527614hypothetical protein 
9HPSH_04185813803..814735 [+], 933188527615cag pathogenicity island protein CagH  CagH
10HPSH_04190814746..815885 [+], 1140188527616cag pathogenicity island protein CagI  CagI
11HPSH_04195815882..816595 [+], 714188527617cag pathogenicity island protein CagL  CagL
12HPSH_04200816678..817598 [-], 921188527618cag pathogenicity island protein CagN  CagN
13HPSH_04205817613..818743 [-], 1131188527619cag pathogenicity island protein CagM  CagM
14HPSH_04210819169..819513 [+], 345188527620cag pathogenicity island protein CagP 
15HPSH_04215819912..823169 [-], 3258188527621cag pathogenicity island protein CagA 
16HPSH_04220823362..823460 [+], 99188527622hypothetical protein 
17HPSH_04225823481..823708 [+], 228188527623cag pathogenicity island protein CagB 
18HPSH_04230823876..824067 [+], 192188527624cag pathogenicity island protein CagC  CagC
19HPSH_04235824137..824232 [+], 96188527625hypothetical protein 
20HPSH_04240824858..825163 [-], 306188527626cag pathogenicity island protein CagQ 
21HPSH_04245825192..825374 [-], 183188527627hypothetical protein 
22HPSH_04250825507..825644 [+], 138188527628hypothetical protein 
23HPSH_04255826078..826677 [+], 600188527629cag pathogenicity island protein CagS 
24HPSH_04260826879..827721 [-], 843188527630cag pathogenicity island protein CagT  CagT
25HPSH_04265827737..828384 [-], 648188527631cag pathogenicity island protein CagU  CagU
26HPSH_04270828660..829418 [+], 759188527632cag pathogenicity island protein CagV  CagV
27HPSH_04275829423..831030 [+], 1608188527633cag pathogenicity island protein CagW  CagW
28HPSH_04280831082..832650 [+], 1569188527634cag pathogenicity island protein CagX  CagX
29HPSH_04285832665..838229 [+], 5565188527635cag pathogenicity island protein CagY  CagY
30HPSH_04290838219..838353 [+], 135188527636hypothetical protein 
31HPSH_04295838366..838965 [+], 600188527637cag pathogenicity island protein CagZ  CagZ
32HPSH_04300838970..839962 [+], 993188527638cag pathogenicity island protein cag alpha  Cagalpha
33HPSH_04305839971..842217 [+], 2247188527639cag pathogenicity island protein Cag beta  Cagbeta
34HPSH_04310842336..842716 [-], 381188527640cag pathogenicity island protein Cag gamma  Caggamma
35HPSH_04315842855..844300 [-], 1446188527641cag pathogenicity island protein Cag delta  Cagdelta
36HPSH_04320844314..844511 [-], 198188527642cag pathogenicity island protein Cag theta 
37HPSH_04325844527..844874 [-], 348188527643cag pathogenicity island protein Cag zeta 
38HPSH_04330845087..845917 [+], 831188527644hypothetical protein 
39HPSH_04335845992..846984 [-], 993188527645hypothetical protein 
40HPSH_04340 (era)846981..847886 [-], 906188527646GTP-binding protein Era 
41HPSH_04345 (hslU)847886..849217 [-], 1332188527647ATP-dependent protease ATP-binding subunit HslU 
 
flank Genes in the 5-Kb flanking regions if available, or non-essential genes in the T4SS gene cluster if any.

Download FASTA format files
Proteins        Genes

Effectors
CagA; Peptidoglycan

The information of protein effectors
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  *
1HPSH_04145 804109..807594 [-], 3486188527607cag pathogenicity island protein CagA  CagA

Download FASTA format files
Proteins        Genes
(1) You Y; He L; Zhang M; Fu J; Gu Y; Zhang B; Tao X; Zhang J (2012). Comparative Genomics of Helicobacter pylori Strains of China Associated with Different Clinical Outcome. PLoS One. 7(6):e38528. [PudMed:22701658] experimental in_silico
(2) Fischer W; Windhager L; Rohrer S; Zeiller M; Karnholz A; Hoffmann R; Zimmer R; Haas R (2010). Strain-specific genes of Helicobacter pylori: genome evolution driven by a novel type IV secretion system and genomic island transfer. Nucleic Acids Res. 38(18):6089-101. [PudMed:20478826] experimental in_silico
 
experimental This literature contains experimental investigation
in_silico This literature contains bioinformatics investigation