SecReT4
T4SS ID477
StrainNeorickettsia risticii str. Illinois
Repliconchromosome [Browse all T4SS(s) in this replicon]
AccessionNC_013009
Location189561..190992; 676486..682248; 701053..254797112; 777907..792487
NameVirB
FunctionNA
ClassificationType IVA; Type P
experimental Experimental investigation has been performed on this T4SS.

T4SS components
ComponentVirB1VirB2VirB3VirB4VirB5VirB6VirB7VirB8VirB9
Number021204022
ComponentVirB10VirB11VirD4
Number111

The information of T4SS components from NC_013009
Region 1: 189561..190992
Click the image to have a larger view
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductComponent
1NRI_0199 (priA)185496..187625 [+], 2130254796593primosomal protein N' 
2NRI_0200187830..188939 [+], 1110254796594hypothetical protein 
3NRI_0201188945..189568 [-], 624254796595exopolysaccharide synthesis protein 
4NRI_0202189561..190361 [-], 801254796596type IV secretion system protein VirB9  VirB9
5NRI_0203190345..190992 [-], 648254796597type IV secretion system protein VirB8  VirB8
6NRI_0204 (grpE)191083..191637 [+], 555254796598co-chaperone GrpE 
7NRI_0205 (trpS)191678..192658 [+], 981254796599tryptophanyl-tRNA synthetase 
8NRI_0206192676..192927 [+], 252254796600hypothetical protein 
9NRI_0207 (rplT)192941..193294 [+], 35425479660150S ribosomal protein L20 
10NRI_0208 (pheS)193291..194268 [+], 978254796602phenylalanyl-tRNA synthetase, alpha subunit 
11NRI_0209 (rpiB)194304..194744 [+], 441254796603ribose 5-phosphate isomerase B 
12NRI_0210 (glyA)194744..195985 [+], 1242254796604serine hydroxymethyltransferase 
 
Region 2: 676486..682248
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#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductComponent
1NRI_0708 (ppa)672658..673176 [+], 519254797081inorganic diphosphatase 
2NRI_0709673441..673878 [-], 438254797082hypothetical protein 
3NRI_0710673958..674314 [-], 357254797083hypothetical protein 
4NRI_0711 (gltX)674374..675603 [-], 1230254797084glutamyl-tRNA synthetase 
5NRI_0712675702..676259 [-], 558254797085membrane protein 
6NRI_0713676486..678411 [-], 1926254797086type IV secretion system component VirD4  VirD4
7NRI_0714 (virB)678443..679438 [-], 996254797087type IV secretion system ATPase VirB11  VirB11
8NRI_0715679445..680686 [-], 1242254797088type IV secretion system protein VirB10  VirB10
9NRI_0716680664..680822 [-], 159254797089type IV secretion system protein VirB10, Frame-Shift 
10NRI_0717 (virB9)680829..681551 [-], 723254797090type IV secretion system protein VirB9  VirB9
11NRI_0718681538..682248 [-], 711254797091type IV secretion system protein VirB8  VirB8
12NRI_0719682490..683551 [-], 1062254797092GTP cyclohydrolase II 
13NRI_0720 (pdhB)683781..684779 [+], 999254797093pyruvate dehydrogenase subunit beta 
14NRI_0721685143..685406 [+], 264254797094hypothetical protein 
15NRI_0722685575..685898 [+], 324254797095hypothetical protein 
 
Region 3: 701053..254797112
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#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductComponent
1NRI_0734696638..696973 [-], 336254797106ATP synthase subunits delta/epsilon 
2NRI_0735 (atpD)696974..698398 [-], 1425254797107F0F1 ATP synthase subunit beta 
3NRI_0736698537..701086 [-], 2550254797108hypothetical protein 
4NRI_0737701053..703200 [-], 2148254797109type IV secretion system protein VirB4  VirB4
5NRI_0738703399..703761 [-], 363254797110type IV secretion system protein VirB2  VirB2
6NRI_0739703655..703771 [-], 117254797111hypothetical protein 
7NRI_0740703972..704319 [-], 348254797112type IV secretion system protein VirB2  VirB2
8NRI_0742704105..704533 [+], 429254797113lipoprotein 
9NRI_0741 (lepA)704505..706295 [-], 1791254797114GTP-binding protein LepA 
10NRI_0743 (lysK)706477..707994 [-], 1518254797115lysyl-tRNA synthetase 
11NRI_0744708427..708906 [+], 480254797116hypothetical protein 
12NRI_0745709092..709970 [-], 879254797117molybdopterin biosynthesis protein MoeB 
13NRI_0746710044..711045 [+], 1002254797118thioredoxin reductase 
14NRI_0747 (hisS)711232..712473 [-], 1242254797119histidyl-tRNA synthetase 
15NRI_0748712454..712741 [-], 288254797120BolA family protein 
16NRI_0749712824..714071 [-], 1248254797121major facilitator family transporter 
17NRI_0750 (lepB)714510..715139 [+], 630254797122signal peptidase I 
18NRI_0751715266..716516 [-], 1251254797123hypothetical protein 
19NRI_0752716564..716740 [+], 177254797124hypothetical protein 
20NRI_0753716790..718130 [+], 1341254797125hypothetical protein 
21NRI_0754718145..718681 [+], 537254797126hypothetical protein 
22NRI_0755718839..719660 [+], 822254797127hypothetical protein 
23NRI_0756 (hemH)719676..720653 [-], 978254797128ferrochelatase 
24NRI_0757720784..721752 [-], 969254797129hypothetical protein 
25NRI_0758 (rpsT)721823..722086 [-], 264254797130ribosomal protein S20 
26NRI_0759722223..722345 [-], 123254797131hypothetical protein 
27NRI_0760 (pyrF)722549..723235 [+], 687254797132orotidine 5'-phosphate decarboxylase 
28NRI_0761723279..723977 [-], 699254797133membrane protein, TerC family 
29NRI_0762724181..724303 [-], 123254797134hypothetical protein 
30NRI_0763724490..725989 [+], 1500254797135propionyl-CoA carboxylase beta chain 
31NRI_0764726091..726654 [+], 564254797136hypothetical protein 
32NRI_0765726820..728142 [+], 1323254797137outer membrane efflux protein 
33NRI_0766 (ispG)728237..729481 [-], 12452547971384-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 
34NRI_0767729534..730241 [-], 708254797139inositol monophosphatase family protein 
35NRI_0768 (pdhA)730337..731305 [-], 969254797140pyruvate dehydrogenase E1 component, alpha subunit 
36NRI_0770734352..734510 [-], 159254797141hypothetical protein 
37NRI_0771734558..734674 [+], 117254797142hypothetical protein 
38NRI_0772734664..735506 [+], 8432547971434-hydroxybenzoate octaprenyltransferase 
39NRI_0773735503..735961 [+], 459254797144flavin reductase family protein 
40NRI_0774736063..736830 [+], 768254797145phosphate import ATP-binding protein PstB 
41NRI_0776737285..737416 [-], 132254797146hypothetical protein 
42NRI_0777 (smpB)737485..737928 [-], 444254797147SsrA-binding protein 
43NRI_0778738175..741015 [+], 2841254797148phosphoribosylformylglycinamidine synthase 
44NRI_0779741054..741206 [-], 153254797149hypothetical protein 
45NRI_0780741571..742842 [-], 1272254797150permease 
46NRI_0781742981..744939 [-], 1959254797151propionyl-CoA carboxylase alpha chain 
47NRI_0782744911..745810 [-], 900254797152ribose-phosphate pyrophosphokinase 
48NRI_0783745819..745968 [-], 150254797153hypothetical protein 
49NRI_0784745988..746530 [-], 543254797154hira-interacting protein 5 
50NRI_0785746611..746997 [+], 387254797155DnaJ domain protein 
51NRI_0787747208..747690 [+], 483254797156NADH dehydrogenase subunit I 
52NRI_0786747652..747789 [-], 138254797157hypothetical protein 
53NRI_0788747811..747954 [-], 144254797158hypothetical protein 
54NRI_0790747917..748561 [+], 645254797159tetrahydrofolate dehydrogenase/cyclohydrolase 
55NRI_0792748829..749227 [-], 399254797160hypothetical protein 
56NRI_0793749304..750665 [+], 1362254797161hypothetical protein 
57NRI_0794750771..751859 [-], 1089254797162Ser/Thr protein phosphatase 
58NRI_0797 (hemA)752494..753714 [+], 12212547971635-aminolevulinate synthase 
59NRI_0798 (rpsU)753743..753937 [-], 195254797164ribosomal protein S21 
60NRI_0799754013..754420 [-], 408254797165cytochrome c-type biogenesis protein CcmE 
61NRI_0800754422..756050 [-], 1629254797166metallo-beta-lactamase family, beta-casp subfamily 
62NRI_0802 (miaB)756450..757814 [+], 1365254797167tRNA-I(6)A37 thiotransferase enzyme MiaB 
63NRI_0801757811..757990 [-], 180254797168hypothetical protein 
64NRI_0804758495..758656 [+], 162254797169hypothetical protein 
65NRI_0805 (phrB)758826..760235 [+], 1410254797170deoxyribodipyrimidine photolyase 
66NRI_0806760267..760989 [-], 723254797171hypothetical protein 
67NRI_0807 (rpsI)761023..761460 [-], 43825479717230S ribosomal protein S9 
68NRI_0808 (rplM)761463..761921 [-], 45925479717350S ribosomal protein L13 
69NRI_0809761985..762626 [-], 642254797174CvpA family protein 
70NRI_0810762627..765116 [-], 2490254797175trap transporter, 4tm/12tm fusion protein 
71NRI_0811765234..765851 [-], 618254797176superoxide dismutase, Fe 
72NRI_0812766033..766623 [+], 591254797177glycoprotease family protein 
73NRI_0813766644..767786 [+], 1143254797178branched-chain amino acid transporter 
74NRI_0814767982..769181 [+], 1200254797179major facilitator family transporter 
75NRI_0815769190..770221 [-], 1032254797180mechanosensitive ion channel family protein 
76NRI_0817770576..771283 [+], 708254797181hypothetical protein 
77NRI_0818771317..771472 [-], 156254797182hypothetical protein 
78NRI_0819 (argD)771476..772465 [+], 990254797183acetylornithine transaminase protein 
79NRI_0820772528..773187 [-], 660254797184peptidyl-prolyl cis-trans isomerase, cyclophilin-type 
80NRI_0821 (purC)773327..774049 [-], 723254797185phosphoribosylaminoimidazole-succinocarboxamide synthase 
81NRI_0822 (ribE)774363..774965 [+], 603254797186riboflavin synthase subunit alpha 
82NRI_0823 (lgt)775070..775870 [+], 801254797187prolipoprotein diacylglyceryl transferase 
83NRI_0824 (coxW)775913..776932 [-], 1020254797188cytochrome c oxidase assembly protein 
84NRI_0825777362..777580 [+], 219254797189ribonuclease P protein component 
85NRI_0826777583..777894 [+], 312254797190hypothetical protein 
86NRI_0827777907..781179 [-], 3273254797191type IV secretion system protein, VirB6 family  VirB6
87NRI_0828781166..784648 [-], 3483254797192type IV secretion system protein, VirB6 family  VirB6
88NRI_0829784683..787202 [-], 2520254797193type IV secretion system protein, VirB6 family  VirB6
89NRI_0830787219..789780 [-], 2562254797194type IV secretion system protein VirB6  VirB6
90NRI_0831789777..792188 [-], 2412254797195type IV secretion system ATPase VirB4  VirB4
91NRI_0832792191..792487 [-], 297254797196type IV secretion system protein VirB3  VirB3
92NRI_0833792817..794628 [-], 1812254797197efflux ABC transporter, heavy metal transporter (HMT) family, permease/ATP-binding protein 
93NRI_0834794731..795798 [-], 1068254797198phospholipase, patatin family 
94NRI_0835795815..795991 [-], 177254797199hypothetical protein 
95NRI_0836796168..797034 [+], 867254797200hypothetical protein 
96NRI_0837797138..798001 [+], 864254797201alpha/beta hydrolase 
97NRI_0838 (nsp1)798127..798909 [+], 783254797202Wsp-like surface protein 
98NRI_0839 (nsp2)799233..800159 [+], 927254797203Wsp-like surface protein 
99NRI_0840800159..800335 [+], 177254797204hypothetical protein 
100NRI_0841 (nsp3)800528..801256 [+], 729254797205Wsp-like surface protein 
101NRI_0842801317..801640 [+], 324254797206preprotein translocase subunit SecG 
102NRI_0843 (pyrG)801615..803279 [+], 1665254797207CTP synthetase 
103NRI_0846803629..805584 [+], 1956254797208hypothetical protein 
104NRI_0847805592..806017 [-], 426254797209N utilization substance protein B 
105NRI_0848806007..806627 [-], 621254797210hypothetical protein 
106NRI_0849 (infA)806670..806951 [-], 282254797211translation initiation factor IF-1 
107NRI_0850807003..807218 [-], 216254797212hypothetical protein 
108NRI_0851807296..807553 [-], 258254797213hypothetical protein 
109NRI_0852807330..807860 [+], 531254797214thiol-disulfide isomerase, thioredoxin family 
110NRI_0853807882..809618 [+], 1737254797215glutathione-regulated potassium-efflux system protein 
111NRI_0854 (guaA)809681..811240 [-], 1560254797216GMP synthase 
112NRI_0855 (mrp)811371..812111 [-], 741254797217Mrp protein 
113NRI_0856 (ompA)812524..813150 [+], 627254797218peptidoglycan-associated lipoprotein (PAL/OmpA) 
114NRI_0857813161..814012 [+], 852254797219hypothetical protein 
115NRI_0858 (gpmI)814082..815554 [+], 1473254797220phosphoglyceromutase 
116NRI_0859815569..816342 [-], 774254797221hypothetical protein 
117NRI_0860 (metG)816506..818071 [+], 1566254797222methionyl-tRNA synthetase 
118NRI_0861 (trx)818107..818415 [-], 309254797223thioredoxin 
119NRI_0862 (rplS)818425..818787 [-], 36325479722450S ribosomal protein L19 
120NRI_0863 (trmD)818811..819467 [-], 657254797225tRNA (guanine-N1)-methyltransferase 
121NRI_0864 (rpmA)819500..819748 [-], 24925479722650S ribosomal protein L27 
122NRI_0865 (rplU)819800..820168 [-], 369254797227ribosomal protein L21 
123NRI_0866 (recR)820211..820801 [-], 591254797228recombination protein RecR 
124NRI_0867820872..821561 [+], 690254797229hypothetical protein 
125NRI_0868821764..822609 [+], 846254797230disulfide oxidoreductase 
126NRI_0869823002..823328 [+], 327254797231hypothetical protein 
127NRI_0870 (ssa1)823570..825075 [+], 150625479723250kDa strain-specific antigen 
128NRI_0871 (ssa2)825199..826737 [+], 153925479723350kDa strain-specific antigen 
129NRI_0872 (ssa3)827285..828586 [+], 130225479723450 kDa strain-specific antigen 
130NRI_0873 (ychF)829039..830091 [+], 1053254797235GTP-dependent nucleic acid-binding protein EngD 
131NRI_0876830405..830518 [-], 114254797236hypothetical protein 
132NRI_0877830506..831852 [-], 1347254797237peptidase, M16 family 
133NRI_0878831855..833168 [-], 1314254797238peptidase, M16 family 
134NRI_0879 (lspA)833181..833684 [-], 504254797239signal peptidase II 
135NRI_0880833739..835094 [-], 1356254797240carboxypeptidase 
136NRI_0881835377..835736 [+], 360254797241hypothetical protein 
137NRI_0882835726..836067 [+], 342254797242hypothetical protein 
138NRI_0883 (rnc)836106..836774 [-], 669254797243ribonuclease III 
139NRI_0884836765..836971 [-], 207254797244iojap-related protein 
140NRI_0885 (mraW)837472..838362 [-], 891254797245S-adenosyl-methyltransferase MraW 
141NRI_0886838492..839145 [-], 654254797246tRNA (guanine-N(7)-)-methyltransferase 
142NRI_0887839239..839922 [-], 684254797247competence protein ComL 
143NRI_0888 (purD)839945..841234 [+], 1290254797248phosphoribosylamine--glycine ligase 
144NRI_0889841383..842147 [-], 765254797249hypothetical protein 
145NRI_0890842171..842914 [-], 744254797250hypothetical protein 
146NRI_0891 (dapA)843339..844265 [+], 927254797251dihydrodipicolinate synthase 
147NRI_0892844412..844567 [-], 156254797252hypothetical protein 
148NRI_0893845094..845522 [+], 429254797253cytochrome b561 family protein 
149NRI_0894845823..846467 [+], 645254797254HAD-superfamily hydrolase, subfamily IA, variant 1 
150NRI_0895846562..847305 [+], 744254797255uracil-DNA glycosylase, family 4 
151NRI_0896847295..848062 [+], 768254797256VacJ lipoprotein 
152NRI_0897848046..848657 [+], 612254797257hypothetical protein 
153NRI_0898848712..848903 [-], 192254797258hypothetical protein 
154NRI_0899 (aprE)849418..850917 [+], 1500254797259secretion protein, HlyD family 
155NRI_0900851064..852194 [+], 11312547972603-dehydroquinate synthase 
156NRI_0901852199..852447 [+], 249254797261TPR repeat region superfamily 
157NRI_0902 (cdsA)852525..853142 [-], 618254797262phosphatidate cytidylyltransferase 
158NRI_0903 (uppS)853338..854030 [-], 693254797263UDP diphosphate synthase 
159NRI_0904 (frr)854027..854584 [-], 558254797264ribosome recycling factor 
160NRI_0905 (pyrH)854609..855310 [-], 702254797265uridylate kinase 
161NRI_0906 (tsf)855317..856189 [-], 873254797266translation elongation factor Ts 
162NRI_0907 (rpsB)856213..857109 [-], 89725479726730S ribosomal protein S2 
163NRI_0908857085..857222 [-], 138254797268hypothetical protein 
164NRI_0909857298..857990 [+], 693254797269ubiquinone/menaquinone biosynthesis methyltransferase UbiE 
165NRI_0910858324..859763 [+], 1440254797270pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase 
166NRI_0911859961..860725 [+], 765254797271phosphomethylpyrimidine kinase 
167NRI_0912860740..861240 [-], 501254797272crossover junction endodeoxyribonuclease RuvC 
168NRI_0913861332..862279 [-], 948254797273malate dehydrogenase 
169NRI_0914862443..862556 [-], 114254797274hypothetical protein 
170NRI_0915 (dut)862627..863076 [+], 450254797275deoxyuridine 5triphosphate nucleotidohydrolase 
171NRI_0916863171..863365 [+], 195254797276hypothetical protein 
172NRI_0917 (gyrA)863371..865980 [+], 2610254797277DNA gyrase, A subunit 
173NRI_0918 (era)866180..867079 [-], 900254797278GTP-binding protein Era 
174NRI_0919 (fabD)867185..868120 [-], 936254797279malonyl CoA-acyl carrier protein transacylase 
175NRI_0920868198..869937 [-], 1740254797280DNA primase 
176NRI_0921 (acpS)869978..870343 [-], 366254797281holo-ACP synthase 
177NRI_0922870508..871674 [+], 1167254797282hypothetical protein 
178NRI_0923 (dcd)871867..872415 [-], 549254797283deoxycytidine triphosphate deaminase 
179NRI_0924872505..872627 [+], 123254797284hypothetical protein 
180NRI_0925 (purK)872886..873914 [+], 1029254797285phosphoribosylaminoimidazole carboxylase, ATPase subunit 
181NRI_0926873996..874631 [-], 636254797286hypothetical protein 
182NRI_0927874710..876107 [+], 1398254797287phage protein 
183NRI_0928 (hemE)876519..877487 [+], 969254797288uroporphyrinogen decarboxylase 
184NRI_0929 (nadA)877537..878493 [+], 957254797289quinolinate synthetase 
185NRI_0930 (coaD)878510..878995 [-], 486254797290pantetheine-phosphate adenylyltransferase 
186NRI_0931879000..879824 [-], 825254797291hypothetical protein 
187NRI_0932879778..879915 [+], 138254797292hypothetical protein 
 
Region 4: 777907..792487
Click the image to have a larger view
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductComponent
1NRI_0821 (purC)773327..774049 [-], 723254797185phosphoribosylaminoimidazole-succinocarboxamide synthase 
2NRI_0822 (ribE)774363..774965 [+], 603254797186riboflavin synthase subunit alpha 
3NRI_0823 (lgt)775070..775870 [+], 801254797187prolipoprotein diacylglyceryl transferase 
4NRI_0824 (coxW)775913..776932 [-], 1020254797188cytochrome c oxidase assembly protein 
5NRI_0825777362..777580 [+], 219254797189ribonuclease P protein component 
6NRI_0826777583..777894 [+], 312254797190hypothetical protein 
7NRI_0827777907..781179 [-], 3273254797191type IV secretion system protein, VirB6 family  VirB6
8NRI_0828781166..784648 [-], 3483254797192type IV secretion system protein, VirB6 family  VirB6
9NRI_0829784683..787202 [-], 2520254797193type IV secretion system protein, VirB6 family  VirB6
10NRI_0830787219..789780 [-], 2562254797194type IV secretion system protein VirB6  VirB6
11NRI_0831789777..792188 [-], 2412254797195type IV secretion system ATPase VirB4  VirB4
12NRI_0832792191..792487 [-], 297254797196type IV secretion system protein VirB3  VirB3
13NRI_0833792817..794628 [-], 1812254797197efflux ABC transporter, heavy metal transporter (HMT) family, permease/ATP-binding protein 
14NRI_0834794731..795798 [-], 1068254797198phospholipase, patatin family 
15NRI_0835795815..795991 [-], 177254797199hypothetical protein 
16NRI_0836796168..797034 [+], 867254797200hypothetical protein 
 
flank Genes in the 5-Kb flanking regions if available, or non-essential genes in the T4SS gene cluster if any.

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Proteins        Genes
(1) Lin M; Zhang C; Gibson K; Rikihisa Y (2009). Analysis of complete genome sequence of Neorickettsia risticii: causative agent of Potomac horse fever. Nucleic Acids Res. 37(18):6076-91. [PudMed:19661282] experimental
 
experimental This literature contains experimental investigation