SecReT4
Effector Protein ID: 33603866
T4SS name [ID]Ptl [379]
Gene symbolptxE
Locus tagBB4893
StrainBordetella bronchiseptica RB50
Repliconchromosome [GenBank: NC_002927] [Browse all T4SS(s) in this replicon]
Location [Strand]5200956..5201318 [+]
Producttoxin subunit 5
Effector typeProtein
DescriptonPtxE
T4CP requirementT4CP Indepedent
Target/EffectionA subunit of pertussis toxin (PT). PT is involved in the colonization of the respiratory tract and the establishment of infection of Bordetella pertussis causing whooping cough
UniProt IDQ7WDU5
KEGG IDbbr:BB4893
PDB IDNA
Domain hit(s) vs Pfam Pertus-S5-tox [PF09276], Evalue: 1e-65, Aligned region: 24..120
Protein Sequence: 120 a.a.     [Download]
>gi|33603866|ref|NP_891426.1| ptxE gene product [Bordetella bronchiseptica RB50]
MHTIASILLSVLGIYSPADVAGPPTHLYKNFTVQELTLKLKDKNQELCLTAFMPGRSLVRACLSDAERTR
GTWFDTMLGFAISAYALKSRIALTVEDSPYPGTPGDLLELQICPLNGYCE
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Nucleotide Sequence: 363 bp     [Download]
>gi|33598993|ref|NC_002927.3|:5200956-5201318 Bordetella bronchiseptica RB50 chromosome, complete genome
ATGCATACCATCGCATCCATCCTGTTGTCCGTGCTCGGCATATACAGCCCGGCCGACGTCGCCGGCCCGC
CGACCCATCTGTACAAGAACTTCACGGTCCAGGAGCTAACCTTGAAACTGAAGGACAAGAATCAGGAGCT
CTGCCTGACCGCCTTCATGCCAGGCAGAAGCCTGGTCCGGGCGTGCCTGTCCGACGCGGAACGCACGCGC
GGCACGTGGTTCGACACCATGCTTGGCTTTGCCATATCCGCGTATGCGCTCAAGAGCCGGATCGCGCTGA
CGGTGGAAGACTCACCGTATCCGGGCACTCCCGGCGATCTGCTCGAACTGCAGATCTGCCCGCTCAACGG
ATATTGCGAATGA
 Primer design

Reference
(1) Parkhill J; Sebaihia M; Preston A; Murphy LD; Thomson N; Harris DE; Holden MT; Churcher CM; Bentley SD; Mungall KL; Cerdeno-Tarraga AM; Temple L; James K; Harris B; Quail MA; Achtman M; Atkin R; Baker S; Basham D; Bason N; Cherevach I; Chillingworth T; Collins M; Cronin A; Davis P; Doggett J; Feltwell T; Goble A; Hamlin N; Hauser H; Holroyd S; Jagels K; Leather S; Moule S; Norberczak H; O'Neil S; Ormond D; Price C; Rabbinowitsch E; Rutter S; Sanders M; Saunders D; Seeger K; Sharp S; Simmonds M; Skelton J; Squares R; Squares S; Stevens K; Unwin L; Whitehead S; Barrell BG; Maskell DJ (2003). Comparative analysis of the genome sequences of Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica. Nat Genet. 35(1):32-40. [PudMed:12910271]