I. Summary
SecReT6 ID106 insolico
StrainBurkholderia sp. 383
Repliconchromosome 2 [Browse all T6SS(s) in this replicon]
T6SS TypeType i; subtype i3
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
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III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1Bcep18194_B15741783268..1784311 [+], 104478062424zinc-containing alcohol dehydrogenase superfamily protein 
2Bcep18194_B15751784393..1785802 [+], 1410780624253-deoxy-D-arabinoheptulosonate-7-phosphate synthase 
3Bcep18194_B15761785703..1786638 [-], 93678062426transposase 
4Bcep18194_B15771786810..1787580 [-], 77178062427hypothetical protein 
5Bcep18194_B15781787577..1792247 [-], 467178062428Rhs family protein  PAAR
6Bcep18194_B15791792244..1793542 [-], 129978062429hypothetical protein 
7Bcep18194_B15801793560..1794183 [-], 62478062430hypothetical protein 
8Bcep18194_B15811794239..1796512 [-], 227478062431Rhs element Vgr protein  TssI
9Bcep18194_B15821796509..1799172 [-], 266478062432ATPase AAA  TssH
10Bcep18194_B15831799185..1800288 [-], 110478062433hypothetical protein  TssG
11Bcep18194_B15841800285..1802156 [-], 187278062434hypothetical protein  TssF
12Bcep18194_B15851802161..1802709 [-], 54978062435hypothetical protein  TssE
13Bcep18194_B15861802726..1803217 [-], 49278062436hypothetical protein  TssD
14Bcep18194_B15871803289..1804797 [-], 150978062437hypothetical protein  TssC
15Bcep18194_B15881804790..1805344 [-], 55578062438hypothetical protein  TssB
16Bcep18194_B15891805418..1806533 [-], 111678062439ImpA-like  TssA
17Bcep18194_B15901806520..1808829 [-], 231078062440serine/threonine protein kinase 
18Bcep18194_B15911808910..1809605 [-], 69678062441hypothetical protein 
19Bcep18194_B15921809587..1813213 [-], 362778062442hypothetical protein  TssM
20Bcep18194_B15931813216..1814538 [-], 132378062443hypothetical protein  TssL
21Bcep18194_B15941814554..1815972 [-], 141978062444hypothetical protein  TssK
22Bcep18194_B15951815969..1816484 [-], 51678062445hypothetical protein  TssJ
23Bcep18194_B15961817013..1817501 [+], 48978062446hypothetical protein 
24Bcep18194_B15971817546..1819003 [+], 145878062447FHA domain-containing protein  Fha
25Bcep18194_B15981819058..1820536 [-], 147978062448diguanylate cyclase 
26Bcep18194_B15991820552..1820797 [-], 24678062449hypothetical protein 
27Bcep18194_B16001820938..1822383 [-], 1446780624502,5-dioxopentanoate dehydrogenase (NAD+) 
28Bcep18194_B16011822536..1823834 [-], 129978062451cytochrome c, class I 
29Bcep18194_B16021823850..1826072 [-], 222378062452aldehyde oxidase 
30Bcep18194_B16031826074..1826529 [-], 45678062453(2Fe-2S)-binding protein 
31Bcep18194_B16041826663..1826962 [-], 30078062454antibiotic biosynthesis monooxygenase 
32Bcep18194_B16051827070..1828128 [-], 105978062455zinc-containing alcohol dehydrogenase superfamily protein 
33Bcep18194_B16061828363..1828983 [-], 62178062456TetR family transcriptional regulator 
34Bcep18194_B16071829291..1830862 [+], 157278062457hypothetical protein 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

(1) Boyer F et al. (2009). Dissecting the bacterial type VI secretion system by a genome wide in silico analysis: what can be learned from available microbial genomic resources. BMC Genomics. 10:104. [PudMed:19284603] in_silico
in_silico This literature contains bioinformatics investigation