SecReT6
I. Summary
SecReT6 ID120 insolico
StrainEscherichia coli UTI89
Repliconchromosome [Browse all T6SS(s) in this replicon]
AccessionNC_007946
Location237565..271647
Comment
FunctionN/A
T6SS TypeType i; subtype i1
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
ComponentTssHTssDTssLTssITssATssBTssCTssETssF
Number121121111
ComponentTssGTssJTssKTssM
Number1111
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III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1UTI89_C0226 (dkgB)233915..234718 [+], 804912092752,5-diketo-D-gluconate reductase B 
2UTI89_C0227234715..235629 [-], 91591209276LysR family transcriptional regulator 
3UTI89_C0228 (yafD)235846..236670 [+], 82591209277hypothetical protein 
4UTI89_C0229 (yafE)236748..237518 [+], 77191209278hypothetical protein 
5UTI89_C0230 (mltD)237565..238923 [-], 135991209279membrane-bound lytic murein transglycosylase D 
6UTI89_C0231 (gloB)238995..239750 [-], 75691209280hydroxyacylglutathione hydrolase 
7UTI89_C0232 (yafS)239766..240506 [+], 74191209281hypothetical protein 
8UTI89_C0233 (rnhA)240503..241081 [-], 57991209282ribonuclease H 
9UTI89_C0234 (dnaQ)241026..241766 [+], 74191209283DNA polymerase III subunit epsilon 
10UTI89_C0236 (yafT)242304..243089 [+], 78691209284aminopeptidase 
11UTI89_C0237243429..243908 [-], 48091209285hypothetical protein  TssD
12UTI89_C0238243926..245368 [-], 144391209286hypothetical protein  TssA
13UTI89_C0239245295..248762 [-], 346891209287hypothetical protein  TssM
14UTI89_C0240248842..250284 [-], 144391209288hypothetical protein  TssA
15UTI89_C0241250289..251032 [-], 74491209289hypothetical protein 
16UTI89_C0242251029..253788 [-], 276091209290hypothetical protein  TssH
17UTI89_C0243253798..254562 [-], 76591209291hypothetical protein  TssL
18UTI89_C0244254567..255913 [-], 134791209292hypothetical protein  TssK
19UTI89_C0245255916..256440 [-], 52591209293hypothetical protein  TssJ
20UTI89_C0246256437..257729 [-], 129391209294hypothetical protein  Fha
21UTI89_C0247257734..258783 [-], 105091209295hypothetical protein  TssG
22UTI89_C0248258747..260588 [-], 184291209296hypothetical protein  TssF
23UTI89_C0249260594..261019 [-], 42691209297hypothetical protein  TssE
24UTI89_C0250261024..262508 [-], 148591209298hypothetical protein  TssC
25UTI89_C0251262531..263034 [-], 50491209299hypothetical protein  TssB
26UTI89_C0252263740..264258 [+], 51991209300hypothetical protein  TssD
27UTI89_C0253264479..266461 [+], 198391209301hypothetical protein  TssI
28UTI89_C0254266568..267614 [+], 104791209302hypothetical protein 
29UTI89_C0255267607..269046 [+], 144091209303hypothetical protein  PAAR
30UTI89_C0256269021..269311 [+], 29191209304hypothetical protein 
31UTI89_C0257270562..271065 [+], 50491209305hypothetical protein 
32UTI89_C0258271135..271647 [+], 51391209306hypothetical protein 
33UTI89_C0259271918..272697 [-], 78091209307hypothetical protein 
34UTI89_C0260 (ykfE)272842..273315 [+], 47491209308C-lysozyme inhibitor 
35UTI89_C0261 (fadE)273358..275802 [-], 2445162138493acyl-CoA dehydrogenase 
36UTI89_C0262 (gmhA)276042..276620 [+], 579162138492phosphoheptose isomerase 
 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.
 






2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.
 






3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.
 







Homology Effector list
ECA2866

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1UTI89_C0252263740..264258 [+], 51991209300hypothetical protein ECA2866

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Proteins        Genes
N/A
(1) Boyer F et al. (2009). Dissecting the bacterial type VI secretion system by a genome wide in silico analysis: what can be learned from available microbial genomic resources. BMC Genomics. 10:104. [PudMed:19284603] in_silico
 
in_silico This literature contains bioinformatics investigation