SecReT6
I. Summary
SecReT6 ID141 insolico
StrainEscherichia coli 536
Repliconchromosome [Browse all T6SS(s) in this replicon]
AccessionNC_008253
Location236887..270972
Comment
FunctionN/A
T6SS TypeType i; subtype i1
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
ComponentTssHTssDTssLTssITssATssBTssCTssETssF
Number121121111
ComponentTssGTssJTssKTssM
Number1111
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III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1ECP_0213 (dkgB)233235..234038 [+], 8041106404222,5-diketo-D-gluconate reductase B 
2ECP_0214234035..234949 [-], 915110640423LysR family transcriptional regulator 
3ECP_0215235166..235990 [+], 825110640424hypothetical protein 
4ECP_0216236068..236838 [+], 771110640425methyltransferase YafE 
5ECP_0217 (mltD)236887..238245 [-], 1359110640426membrane-bound lytic murein transglycosylase D 
6ECP_0218238317..239072 [-], 756110640427hydroxyacylglutathione hydrolase 
7ECP_0219239103..239828 [+], 726110640428hypothetical protein 
8ECP_0220 (rnhA)239825..240292 [-], 468110640429ribonuclease H 
9ECP_0221240348..241088 [+], 741110640430DNA polymerase III subunit epsilon 
10ECP_0223241626..242411 [+], 786110640431lipoprotein 
11ECP_0224242751..243251 [-], 501110640432hypothetical protein  TssD
12ECP_0225243248..244606 [-], 1359110640433hypothetical protein  TssA
13ECP_0226244617..248144 [-], 3528110640434IcmF-like protein  TssM
14ECP_0227248164..249672 [-], 1509110640435hypothetical protein  TssA
15ECP_0228249611..250354 [-], 744110640436hypothetical protein 
16ECP_0229250351..253113 [-], 2763110640437Clp ATPase  TssH
17ECP_0230253123..253887 [-], 765110640438hypothetical protein  TssL
18ECP_0231253892..255238 [-], 1347110640439hypothetical protein  TssK
19ECP_0232255241..255765 [-], 525110640440lipoprotein  TssJ
20ECP_0233255762..257150 [-], 1389110640441hypothetical protein  Fha
21ECP_0234257059..258108 [-], 1050110640442hypothetical protein  TssG
22ECP_0235258072..259922 [-], 1851110640443hypothetical protein  TssF
23ECP_0236259919..260344 [-], 426110640444hypothetical protein  TssE
24ECP_0237260349..261833 [-], 1485110640445hypothetical protein  TssC
25ECP_0238261856..262359 [-], 504110640446hypothetical protein  TssB
26ECP_0239263065..263583 [+], 519110640447hemolysin co-regulated protein  TssD
27ECP_0240263804..265786 [+], 1983110640448Vgr-like protein  TssI
28ECP_0241265893..266939 [+], 1047110640449hypothetical protein 
29ECP_0242266932..268371 [+], 1440110640450hypothetical protein  PAAR
30ECP_0243268346..268636 [+], 291110640451hypothetical protein 
31ECP_0244268894..269073 [+], 180110640452H repeat-containing Rhs element protein 
32ECP_0246269350..269658 [+], 309110640453H repeat-containing Rhs element protein 
33ECP_0247269887..270390 [+], 504110640454hypothetical protein 
34ECP_0248270484..270972 [+], 489110640455hypothetical protein 
35ECP_0249271243..272013 [-], 771110640456hypothetical protein 
36ECP_0250272167..272640 [+], 474110640457C-lysozyme inhibitor 
37ECP_0251 (fadE)272683..275127 [-], 2445110640458acyl-CoA dehydrogenase 
38ECP_0252 (gmhA)275367..275945 [+], 579110640459phosphoheptose isomerase 
 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.
 






2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.
 






3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.
 







Homology Effector list
ECA2866

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1ECP_0239263065..263583 [+], 519110640447hemolysin co-regulated protein ECA2866

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Proteins        Genes
N/A
(1) Boyer F et al. (2009). Dissecting the bacterial type VI secretion system by a genome wide in silico analysis: what can be learned from available microbial genomic resources. BMC Genomics. 10:104. [PudMed:19284603] in_silico
 
in_silico This literature contains bioinformatics investigation