SecReT6
I. Summary
SecReT6 ID165 insolico
StrainBurkholderia mallei SAVP1
Repliconchromosome II [Browse all T6SS(s) in this replicon]
AccessionNC_008784
Location607360..636112
Comment
FunctionN/A
T6SS TypeType i; subtype i1
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
ComponentTssHTssDTssLTssITssATssBTssCTssETssF
Number111111111
ComponentTssGTssJTssKTssM
Number1111
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III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1BMASAVP1_0597602829..603854 [+], 1026121597241N-acetylmuramoyl-L-alanine amidase 
2BMASAVP1_0598604142..605362 [+], 1221121597125hypothetical protein 
3BMASAVP1_0599 (bimA)605940..606518 [+], 579121596482intracellular motility protein A 
4BMASAVP1_0600606598..606975 [+], 378121598048lipoprotein 
5BMASAVP1_0601607360..609252 [-], 1893121597840hypothetical protein  TssA
6BMASAVP1_0602 (virG)609249..609986 [-], 738121597699DNA-binding response regulator  VirG
7BMASAVP1_0603609983..611827 [-], 1845121597055sensor histidine kinase  VirA
8BMASAVP1_0604612087..612581 [+], 495121598065hypothetical protein  TssB
9BMASAVP1_0605612578..614104 [+], 1527121597456hypothetical protein  TssC
10BMASAVP1_0606614324..614833 [+], 510121596640hypothetical protein  TssD
11BMASAVP1_0607614826..615287 [+], 462121598024hypothetical protein  TssE
12BMASAVP1_0608615324..617066 [+], 1743121597273hypothetical protein  TssF
13BMASAVP1_0609617054..618076 [+], 1023121597583hypothetical protein  TssG
14BMASAVP1_0610618063..621155 [+], 3093121596593ATP-dependent Clp protease, ATP-binding subunit ClpB  TssH
15BMASAVP1_0611621182..624205 [+], 3024121597345Rhs element Vgr protein  TssI
16BMASAVP1_0612624231..626873 [+], 2643121596551pentapeptide repeat-containing protein 
17BMASAVP1_0613626891..627955 [+], 1065121597558hypothetical protein 
18BMASAVP1_0614628075..628713 [+], 639121596857hypothetical protein 
19BMASAVP1_0615628742..629134 [+], 393121597049hypothetical protein 
20BMASAVP1_0616629144..629941 [+], 798121598014hypothetical protein  TssJ
21BMASAVP1_0617629938..631371 [+], 1434121597385hypothetical protein  TssK
22BMASAVP1_0618631368..632033 [+], 666121596665hypothetical protein  TssL
23BMASAVP1_0619632045..636112 [+], 4068121598086hypothetical protein  TssM
24BMASAVP1_0620636109..636270 [+], 162121597122hypothetical protein 
25BMASAVP1_0621636274..636474 [-], 201121597330hypothetical protein 
26BMASAVP1_0623636629..638053 [+], 1425121596930hypothetical protein  BMAA0729 (e)
27BMASAVP1_0622638013..638192 [-], 180121597887hypothetical protein 
28BMASAVP1_0624638271..638390 [-], 120121597651hypothetical protein 
29BMASAVP1_0626638752..639147 [+], 396121596646GTP cyclohydrolase I 
30BMASAVP1_0625639137..639274 [-], 138121597387hypothetical protein 
31BMASAVP1_0627639297..639584 [+], 288121597130integrase, catalytic region 
32BMASAVP1_0628639741..640004 [+], 264121598178IS407A, transposase OrfA 
33BMASAVP1_0629640028..640861 [+], 834121598001IS407A, transposase OrfB 
 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.
 






2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.
 






3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.
 







Homology Effector list
BMAA0742 , BMAA0729, BMAA0737

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1BMASAVP1_0606614324..614833 [+], 510121596640hypothetical protein BMAA0742
2BMASAVP1_0623636629..638053 [+], 1425121596930hypothetical protein BMAA0729
3BMASAVP1_0611621182..624205 [+], 3024121597345Rhs element Vgr protein BMAA0737

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Proteins        Genes
N/A
N/A