SecReT6
I. Summary
SecReT6 ID178 insolico
StrainBurkholderia pseudomallei 668
Repliconchromosome I [Browse all T6SS(s) in this replicon]
AccessionNC_009074
Location3546300..3566286
Comment
FunctionN/A
T6SS TypeType i; subtype i4b
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
ComponentTssHTssDTssLTssITssATssBTssCTssETssF
Number111011111
ComponentTssGTssJTssKTssM
Number1111
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III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1BURPS668_36203542443..3543891 [+], 1449284159962TolC family type I secretion outer membrane protein 
2BURPS668_36213543888..3544025 [+], 138126439355hypothetical protein 
3BURPS668_36223544101..3545051 [-], 951126442042hypothetical protein 
4BURPS668_36233545063..3546028 [+], 966126438736D-alanyl-D-alanine carboxypeptidase 
5BURPS668_36243546179..3546292 [+], 114126440299hypothetical protein 
6BURPS668_36253546300..3550193 [+], 3894126440145hypothetical protein  TssM
7BURPS668_36263550190..3551179 [+], 990126439251hypothetical protein 
8BURPS668_36273551184..3552116 [+], 933126440077ompA family protein  TagL
9BURPS668_36283552315..3553436 [-], 1122126441470ImpA-related N-terminal family protein  TssA
10BURPS668_36293553526..3556195 [-], 2670126438408ClpA/B type protease  TssH
11BURPS668_36303556229..3557329 [-], 1101126439645hypothetical protein  TssG
12BURPS668_36313557293..3559131 [-], 1839126440612hypothetical protein  TssF
13BURPS668_36323559211..3559693 [-], 483126441892hypothetical protein  TssE
14BURPS668_36333559751..3560254 [-], 504126439263hypothetical protein  TssD
15BURPS668_36343560327..3561817 [-], 1491126442286hypothetical protein  TssC
16BURPS668_36353561834..3562352 [-], 519126440974hypothetical protein  TssB
17BURPS668_36363562389..3563024 [-], 636126439636hypothetical protein 
18BURPS668_36373563186..3563323 [-], 138126438770hypothetical protein 
19BURPS668_36383563435..3564049 [+], 615126441329lipoprotein  TssJ
20BURPS668_36393564098..3565504 [+], 1407126442128hypothetical protein  TssK
21BURPS668_36403565501..3566286 [+], 786126441100hypothetical protein  TssL
22BURPS668_3641 (intB)3566772..3567110 [-], 339126440028Phage integrase 
23BURPS668_36423569704..3569967 [+], 264126440666hypothetical protein 
24BURPS668_36433569991..3570824 [+], 834126439324TnpB 
 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.
 






2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.
 






3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.
 







Homology Effector list
BTH_I2697 , BTH_I2705, BCAL0343, BTH_I0068, BTH_I2698, BTH_I2693, BTH_I3226, BTH_I3225, BTH_II0090, BTH_II0310

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1BURPS668_15851551963..1555298 [+], 3336126438749Rhs element Vgr protein BTH_I2697
2BURPS668_15801544522..1547329 [+], 2808126439104Rhs element Vgr protein BTH_I2705
3BURPS668_36333559751..3560254 [-], 504126439263hypothetical protein BCAL0343
4BURPS668_008075977..76417 [+], 441126439768hypothetical protein BTH_I0068
5BURPS668_15841549545..1551854 [+], 2310126441542hypothetical protein BTH_I2698
6BURPS668_15901557430..1560270 [+], 2841126441823Rhs element Vgr protein BTH_I2693
7BURPS668_A0128111023..113263 [+], 2241126443653hypothetical protein BTH_I3226
8BURPS668_A0127108223..111009 [+], 2787126444328putative Rhs element Vgr protein BTH_I3225
9BURPS668_A16951646115..1647458 [-], 1344126444360Type V secretory pathway, adhesin AidA BTH_II0090
10BURPS668_A29132765611..2766516 [+], 906126444367outer membrane protein BTH_II0310

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Proteins        Genes

Homology Immunity protein list
BTH_I2700, BTH_I0069

Immunity protein identified
#Locus tag(Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1BURPS668_15821548350..1548859 [+], 510126440343hypothetical protein BTH_I2700
2BURPS668_008176404..76772 [+], 369126442147lipoprotein BTH_I0069

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Proteins        Genes
N/A