I. Summary
SecReT6 ID186 insolico
StrainBurkholderia pseudomallei 1106a
Repliconchromosome II [Browse all T6SS(s) in this replicon]
T6SS TypeType i; subtype i3
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
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III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1BURPS1106A_A0227210832..211110 [-], 279126457849hypothetical protein 
2BURPS1106A_A0228 (pvcA)211366..212424 [+], 1059126456717pyoverdine chromophore biosynthetic protein PvcA 
3BURPS1106A_A0229 (pvcB)212421..213335 [+], 915126455993pyoverdine biosynthesis protein PvcB 
4BURPS1106A_A0230 (pvcC)213361..214845 [+], 1485126456550chromophore biosynthetic protein PvcC 
5BURPS1106A_A0231 (asnB)214891..216759 [+], 1869126455483asparagine synthase 
6BURPS1106A_A0232216788..217759 [+], 972126458559zinc-binding dehydrogenase family oxidoreductase 
7BURPS1106A_A0233217814..218740 [+], 927126457734aromatic ring-opening dioxygenase 
8BURPS1106A_A0234218984..220330 [-], 1347126457796LysR family transcriptional regulator 
9BURPS1106A_A0235220915..221148 [-], 234126456829hypothetical protein 
10BURPS1106A_A0236221168..225244 [-], 4077126455953ImcF/SciS family protein  TssM
11BURPS1106A_A0237225273..226538 [-], 1266126457554hypothetical protein  TssL
12BURPS1106A_A0238226627..227973 [-], 1347126457249hypothetical protein  TssK
13BURPS1106A_A0239 (sciN)227995..228498 [-], 504126456114SciN protein  TssJ
14BURPS1106A_A0241228511..228627 [+], 117126457243hypothetical protein 
15BURPS1106A_A0240 (sciM)228605..229090 [-], 486126457863SciM protein  TssD
16BURPS1106A_A0242229207..230706 [-], 1500126456800hypothetical protein  TssC
17BURPS1106A_A0243230741..231322 [-], 582126455789hypothetical protein  TssB
18BURPS1106A_A0244 (clpB)231358..234297 [-], 2940126456099chaperone clpB  TssH
19BURPS1106A_A0245234829..235551 [+], 723126458617hypothetical protein 
20BURPS1106A_A0246235548..236513 [+], 966126458224ImpE/SciE family protein  TagJ
21BURPS1106A_A0247236500..237081 [+], 582126457375hypothetical protein  TssE
22BURPS1106A_A0248237112..239001 [+], 1890126456248hypothetical protein  TssF
23BURPS1106A_A0249239001..240086 [+], 1086126455565hypothetical protein  TssG
24BURPS1106A_A0250240083..241198 [+], 1116226830796ImpA-related N-terminal family protein  TssA
25BURPS1106A_A0251241270..243597 [+], 2328126458536Rhs element Vgr protein  TssI
26BURPS1106A_A0252243629..246106 [+], 2478126455703pentapeptide repeat-containing protein 
27BURPS1106A_A0253246103..247185 [+], 1083126456567pentapeptide repeat-containing protein 
28BURPS1106A_A0254247179..247370 [+], 192126455784hypothetical protein 
29BURPS1106A_A0255247367..248026 [+], 660126456517hypothetical protein 
30BURPS1106A_A0256248067..248447 [+], 381126457174hypothetical protein 
31BURPS1106A_A0257248514..248690 [+], 177126455815hypothetical protein 
32BURPS1106A_A0258249187..251103 [-], 1917126457552hypothetical protein 
33BURPS1106A_A0259251086..251346 [+], 261126458277hypothetical protein 
34BURPS1106A_A0260251443..252336 [-], 894126455777LysR family transcriptional regulator 
35BURPS1106A_A0261252432..253208 [+], 777126456447quinone family NAD(P)H dehydrogenase 
36BURPS1106A_A0262253123..253674 [+], 552126458581AraC family transcriptional regulator 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

(1) Boyer F et al. (2009). Dissecting the bacterial type VI secretion system by a genome wide in silico analysis: what can be learned from available microbial genomic resources. BMC Genomics. 10:104. [PudMed:19284603] in_silico
in_silico This literature contains bioinformatics investigation