SecReT6
I. Summary
SecReT6 ID188 insolico
StrainBurkholderia pseudomallei 1106a
Repliconchromosome II [Browse all T6SS(s) in this replicon]
AccessionNC_009078
Location1987602..2017853
Comment
FunctionN/A
T6SS TypeType i; subtype i1
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
ComponentTssHTssDTssLTssITssATssBTssCTssETssF
Number111111111
ComponentTssGTssJTssKTssM
Number1111
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III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1BURPS1106A_A20151983004..1983129 [-], 126126455855hypothetical protein 
2BURPS1106A_A20161983119..1983298 [-], 180126458374hypothetical protein 
3BURPS1106A_A20181983396..1984421 [+], 1026126456376putative N-acetylmuramoyl-L-alanine amidase 
4BURPS1106A_A20171984418..1984531 [-], 114126457079hypothetical protein 
5BURPS1106A_A20191984549..1985949 [+], 1401126456936hypothetical protein 
6BURPS1106A_A2020 (bimA)1986140..1987522 [+], 1383126456219intracellular motility protein A 
7BURPS1106A_A20211987602..1987979 [+], 378126458191putative lipoprotein 
8BURPS1106A_A20221988222..1990093 [-], 1872126457583ImpA-related N-terminal family protein  TssA
9BURPS1106A_A20231990084..1990821 [-], 738126456477DNA-binding response regulator  VirG
10BURPS1106A_A20241990818..1992662 [-], 1845126456061sensor histidine kinase  VirA
11BURPS1106A_A20251992922..1993416 [+], 495126455594hypothetical protein  TssB
12BURPS1106A_A20261993440..1994939 [+], 1500126456298hypothetical protein  TssC
13BURPS1106A_A20271995159..1995668 [+], 510126457376hcp protein  TssD
14BURPS1106A_A20281995661..1996122 [+], 462126458109hypothetical protein  TssE
15BURPS1106A_A20291996159..1997901 [+], 1743126456422hypothetical protein  TssF
16BURPS1106A_A20301997865..1998911 [+], 1047126458585hypothetical protein  TssG
17BURPS1106A_A20311998898..2001954 [+], 3057126458158ATP-dependent Clp protease, ATP-binding subunit ClpB  TssH
18BURPS1106A_A20322001981..2005004 [+], 3024126457275Rhs element Vgr protein  TssI
19BURPS1106A_A20332005030..2007663 [+], 2634126455886pentapeptide repeat-containing protein 
20BURPS1106A_A20342007681..2008745 [+], 1065126457678pentapeptide repeat-containing protein 
21BURPS1106A_A20352008859..2009497 [+], 639126457932hypothetical protein 
22BURPS1106A_A20362009526..2009918 [+], 393126455497hypothetical protein 
23BURPS1106A_A20372009928..2010725 [+], 798126456151hypothetical protein  TssJ
24BURPS1106A_A20382010722..2012155 [+], 1434126456857hypothetical protein  TssK
25BURPS1106A_A20392012152..2012817 [+], 666126457277hypothetical protein  TssL
26BURPS1106A_A20402012829..2016833 [+], 4005126458165hypothetical protein  TssM
27BURPS1106A_A20412016849..2016998 [+], 150126456234hypothetical protein 
28BURPS1106A_A20422017002..2017187 [-], 186126456758hypothetical protein 
29BURPS1106A_A20432017683..2017853 [-], 171126457716hypothetical protein 
30BURPS1106A_A20452017927..2018781 [+], 855126457393hypothetical protein  BMAA0729 (e)
31BURPS1106A_A20442018741..2018986 [-], 246126458368hypothetical protein 
32BURPS1106A_A20462018999..2019118 [-], 120126456345hypothetical protein 
33BURPS1106A_A20472019189..2019392 [-], 204126455574hypothetical protein 
34BURPS1106A_A20482019454..2019576 [+], 123126458458hypothetical protein 
35BURPS1106A_A20502019480..2019875 [+], 396126455897putative GTP cyclohydrolase I 
36BURPS1106A_A20492019865..2020002 [-], 138126456930hypothetical protein 
37BURPS1106A_A20512020025..2020312 [+], 288126458380ChnZ 
38BURPS1106A_A20522020936..2022480 [-], 1545126458061hypothetical protein 
39BURPS1106A_A20532022497..2022700 [-], 204126456952hypothetical protein 
 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

Download FASTA format files
Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.
 






2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.
 






3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.
 







Homology Effector list
BMAA0737 , BMAA0742, BMAA0729

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1BURPS1106A_A20322001981..2005004 [+], 3024126457275Rhs element Vgr protein BMAA0737
2BURPS1106A_A20271995159..1995668 [+], 510126457376hcp protein BMAA0742
3BURPS1106A_A20452017927..2018781 [+], 855126457393hypothetical protein BMAA0729

Download FASTA format files
Proteins        Genes
N/A
(1) Boyer F et al. (2009). Dissecting the bacterial type VI secretion system by a genome wide in silico analysis: what can be learned from available microbial genomic resources. BMC Genomics. 10:104. [PudMed:19284603] in_silico
 
in_silico This literature contains bioinformatics investigation