SecReT6
I. Summary
SecReT6 ID217 insolico
StrainPseudomonas aeruginosa PA7
Repliconchromosome [Browse all T6SS(s) in this replicon]
AccessionNC_009656
Location161170..187540
Comment
FunctionN/A
T6SS TypeType i; subtype i3
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
ComponentTssHTssDTssLTssITssATssBTssCTssETssF
Number111211111
ComponentTssGTssJTssKTssM
Number1111
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III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1PSPA7_0145156649..159747 [-], 3099152984686serine/threonine protein kinase PpkA  PpkA
2PSPA7_0146159755..160483 [-], 729152986292putative phosphoprotein phosphatase  PppA
3PSPA7_0147160493..161173 [-], 681152987384hypothetical protein  TagF
4PSPA7_0148161170..164700 [-], 3531152984454hypothetical protein  TssM
5PSPA7_0149164697..166046 [-], 1350152985769hypothetical protein  TssL
6PSPA7_0150166053..167387 [-], 1335152988561hypothetical protein  TssK
7PSPA7_0151167404..167868 [-], 465152985140putative lipoprotein  TssJ
8PSPA7_0152167913..169439 [-], 1527152985795hypothetical protein  Fha
9PSPA7_0153169449..169592 [+], 144152989219hypothetical protein 
10PSPA7_0154169807..170838 [+], 1032152984264hypothetical protein  TssA
11PSPA7_0155170927..171445 [+], 519152983480hypothetical protein  TssB
12PSPA7_0156171458..172954 [+], 1497152984184hypothetical protein  TssC
13PSPA7_0157173030..173518 [+], 489152985902hypothetical protein  TssD
14PSPA7_0158173677..174462 [+], 786152988565virulence protein, SciE type  TagJ
15PSPA7_0159174464..174973 [+], 510152984195hypothetical protein  TssE
16PSPA7_0160174970..176829 [+], 1860152988188hypothetical protein  TssF
17PSPA7_0161176793..177839 [+], 1047152986386hypothetical protein  TssG
18PSPA7_0162177832..180540 [+], 2709152989614type VI secretion ATPase  TssH
19PSPA7_0163180575..182515 [+], 1941152987570hypothetical protein  TssI
20PSPA7_0164182522..182635 [-], 114152987514hypothetical protein 
21PSPA7_0165182642..182767 [-], 126152986670hypothetical protein 
22PSPA7_0166182778..183311 [-], 534152986602hypothetical protein 
23PSPA7_0167183308..184612 [-], 1305152985744PAAR motif-containing protein  Tse6 (e)
24PSPA7_0168184628..185062 [-], 435152987036hypothetical protein 
25PSPA7_0169185315..187540 [+], 2226152983873hypothetical protein  TssI
26PSPA7_0170187569..188018 [+], 450152986466hypothetical protein 
27PSPA7_0171188035..189147 [+], 1113152985103hypothetical protein 
28PSPA7_0172189144..190181 [+], 10381529868463-oxoacyl-(acyl carrier protein) synthase 
29PSPA7_0173190181..191344 [+], 1164152989562hypothetical protein 
30PSPA7_0174191721..192281 [+], 561152984217hypothetical protein 
 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.
 






2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.
 






3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.
 







Homology Effector list
PA0095 , PA2702, PA2684, PA0093, PA3484, PA0085, PA2685, PA1844, PA0091

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1PSPA7_0169185315..187540 [+], 2226152983873hypothetical protein PA0095
2PSPA7_39794123474..4123950 [+], 477152984462hypothetical protein PA2702
3PSPA7_39594099703..4103662 [-], 3960152985313hypothetical protein PA2684
4PSPA7_0167183308..184612 [-], 1305152985744PAAR motif-containing protein PA0093
5PSPA7_16421679339..1680565 [-], 1227152985781hypothetical protein PA3484
6PSPA7_0157173030..173518 [+], 489152985902hypothetical protein PA0085
7PSPA7_39604103712..4105781 [-], 2070152985978hypothetical protein PA2685
8PSPA7_34483574266..3574736 [+], 471152987248hypothetical protein PA1844
9PSPA7_0163180575..182515 [+], 1941152987570hypothetical protein PA0091

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Proteins        Genes

Homology Immunity protein list
Tsi5, PA2703, PA3485, PA1845

Immunity protein identified
#Locus tag(Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1PSPA7_39584099515..4099706 [-], 192152983834hypothetical protein Tsi5
2PSPA7_39804123960..4124193 [+], 234152988085hypothetical protein PA2703
3PSPA7_16411678905..1679342 [-], 438152988990hypothetical protein PA3485
4PSPA7_34473573704..3574222 [+], 519152989292hypothetical protein PA1845

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Proteins        Genes
(1) Barret M et al. (2011). Genomic analysis of the type VI secretion systems in Pseudomonas spp.: novel clusters and putative effectors uncovered. Microbiology. 157(Pt 6):1726-39. [PudMed:21474537] in_silico
 
in_silico This literature contains bioinformatics investigation