SecReT6
I. Summary
SecReT6 ID258 insolico
StrainYersinia pseudotuberculosis YPIII
Repliconchromosome [Browse all T6SS(s) in this replicon]
AccessionNC_010465
Location1619849..1653371
Comment
FunctionN/A
T6SS TypeType i; subtype i3
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
ComponentTssHTssDTssLTssITssATssBTssCTssETssF
Number121111111
ComponentTssGTssJTssKTssM
Number1111
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III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1YPK_14641616059..1617153 [+], 1095170023705murein hydrolase B 
2YPK_14651618395..1618997 [+], 603170023706LuxR family transcriptional regulator 
3YPK_14661619370..1619852 [-], 483170023707hypothetical protein 
4YPK_14671619849..1621531 [-], 1683170023708OmpA/MotB domain-containing protein  TagL
5YPK_14681621532..1622233 [-], 702170023709hypothetical protein 
6YPK_14691622230..1623567 [-], 1338170023710hypothetical protein 
7YPK_14701623607..1624638 [-], 1032170023711hypothetical protein 
8YPK_14711624645..1625838 [-], 1194170023712ImpA domain-containing protein  TssA
9YPK_14721625937..1626962 [-], 1026170023713type VI secretion protein  TssG
10YPK_14731626962..1628842 [-], 1881170023714type VI secretion protein  TssF
11YPK_14741629626..1632283 [+], 2658170023715type VI secretion ATPase  TssH
12YPK_14751632494..1633039 [+], 546170023716fimbrial protein 
13YPK_14761633196..1633957 [+], 762170023717pili assembly chaperone 
14YPK_14771634085..1636757 [+], 2673170023718fimbrial biogenesis outer membrane usher protein 
15YPK_14781636742..1637350 [+], 609170023719fimbrial protein 
16YPK_14791637456..1637980 [+], 525170023720type VI secretion protein  TssB
17YPK_14801638004..1639506 [+], 1503170023721EvpB family type VI secretion protein  TssC
18YPK_14811639755..1640324 [+], 570170023722Hcp1 family type VI secretion system effector  TssD
19YPK_14821640577..1641137 [+], 561170023723hypothetical protein  TssJ
20YPK_14831641141..1642490 [+], 1350170023724type VI secretion protein  TssK
21YPK_14841642487..1643863 [+], 1377170023725type VI secretion system OmpA/MotB family protein  TssL
22YPK_14851643872..1647699 [+], 3828170023726type VI secretion protein IcmF  TssM
23YPK_14861648026..1650794 [+], 2769170023727ImpA family type VI secretion-associated protein  TssI
24YPK_14871650893..1651153 [+], 261170023728hypothetical protein  PAAR
25YPK_14881651153..1652001 [+], 849170023729hypothetical protein 
26YPK_14891652021..1652827 [+], 807170023730virulence protein SciE type  TagJ
27YPK_14901652892..1653371 [+], 480170023731type VI secretion system lysozyme-like protein  TssE
28YPK_14911653396..1653743 [+], 348170023732hypothetical protein 
29YPK_14921653818..1654159 [-], 342170023733alkylphosphonate utilization operon protein PhnA 
30YPK_14931654535..1656574 [-], 2040170023734hypothetical protein 
31YPK_14941656579..1657121 [-], 543170023735LemA family protein 
32YPK_14951657738..1658205 [+], 468170023736hypothetical protein 
 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.
 






2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.
 






3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.
 







Homology Effector list
ROD_27741

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1YPK_14811639755..1640324 [+], 570170023722Hcp1 family type VI secretion system effector ROD_27741

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Proteins        Genes
N/A
(1) Zhang W et al. (2012). A type VI secretion system regulated by OmpR in Yersinia pseudotuberculosis functions to maintain intracellular pH homeostasis. Environ Microbiol. 15(2):557-69. [PudMed:23094603] experimental
(2) Zhang W et al. (2011). Modulation of a thermoregulated type VI secretion system by AHL-dependent quorum sensing in Yersinia pseudotuberculosis. Arch Microbiol. 193(5):351-63. [PudMed:21298257]
 
experimental This literature contains experimental investigation