SecReT6
I. Summary
SecReT6 ID293 insolico
StrainSalmonella enterica subsp. enterica serovar Newport str. SL254
Repliconchromosome [Browse all T6SS(s) in this replicon]
AccessionNC_011080
Location306645..335310
Comment
FunctionN/A
T6SS TypeType i; subtype i3
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
ComponentTssHTssDTssLTssITssATssBTssCTssETssF
Number121111111
ComponentTssGTssJTssKTssM
Number1111
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III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1SNSL254_A0285 (mltD)301903..303123 [-], 1221194443861membrane-bound lytic murein transglycosylase D 
2SNSL254_A0286 (gloB)303342..304097 [-], 756194444358hydroxyacylglutathione hydrolase 
3SNSL254_A0287304132..304854 [+], 723194443090methyltransferase 
4SNSL254_A0288 (rnhA)304851..305318 [-], 468194442619ribonuclease H 
5SNSL254_A0289 (dnaQ)305373..306113 [+], 741194445947DNA polymerase III subunit epsilon 
6SNSL254_A0291306645..307694 [-], 1050194446459ImpA-related N- family protein  TssA
7SNSL254_A0292307711..308706 [-], 996194444207type VI secretion protein  TssG
8SNSL254_A0293 (vasA)308703..310586 [-], 1884194443419type VI secretion protein  TssF
9SNSL254_A0294310602..311096 [-], 495194445579type VI secretion system lysozyme-like protein  TssE
10SNSL254_A0295311093..311917 [-], 825194445082SciE protein  TagJ
11SNSL254_A0296311904..312806 [-], 903194446571hypothetical protein 
12SNSL254_A0297312883..313014 [-], 132194446081hypothetical protein 
13SNSL254_A0298 (clpV)313174..315813 [+], 2640194445862ClpV1 family type VI secretion ATPase  TssH
14SNSL254_A0299315913..316455 [+], 543194442796type VI secretion protein  TssB
15SNSL254_A0300316479..317987 [+], 1509194442296EvpB family type VI secretion protein  TssC
16SNSL254_A0301318413..318838 [+], 426194444424hypothetical protein  STY0301 (i)
17SNSL254_A0302319075..319560 [+], 486194442474hemolysin-coregulated protein  TssD
18SNSL254_A0303319863..320348 [+], 486194442957hypothetical protein  STM0277 (e)
19SNSL254_A0304320384..320716 [+], 333194443478hypothetical protein  STM0278 (i)
20SNSL254_A0305320859..321344 [+], 486194443822hemolysin-coregulated protein  TssD
21SNSL254_A0306321456..321947 [+], 492194446584type VI secretion lipoprotein  TssJ
22SNSL254_A0307321951..323294 [+], 1344194444887type VI secretion protein  TssK
23SNSL254_A0308323291..324595 [+], 1305194443139hypothetical protein  TssL
24SNSL254_A0309324600..325373 [+], 774194445934hypothetical protein 
25SNSL254_A0310325785..326006 [+], 222194443975SciR protein 
26SNSL254_A0311 (icmF)326040..329909 [+], 3870194442352type VI secretion protein IcmF  TssM
27SNSL254_A0312329909..330676 [+], 768194443833hypothetical protein 
28SNSL254_A0313331279..331635 [+], 357194444482hypothetical protein 
29SNSL254_A0314331644..331766 [+], 123194444504hypothetical protein 
30SNSL254_A0315331793..332179 [+], 387194445158hypothetical protein 
31SNSL254_A0317332602..332724 [+], 123194445674hypothetical protein 
32SNSL254_A0318332866..333075 [+], 210194442538hypothetical protein 
33SNSL254_A0319333121..335310 [+], 2190194442493Rhs family protein  TssI
34SNSL254_A0320335334..335780 [+], 447194445631hypothetical protein 
35SNSL254_A0321335799..339878 [+], 4080194443828Rhs family protein  PAAR
 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.
 






2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.
 






3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.
 







Homology Effector list
SciK , STM0277, SciK, Hcp, STY2606

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1SNSL254_A0302319075..319560 [+], 486194442474hemolysin-coregulated protein SciK
2SNSL254_A0303319863..320348 [+], 486194442957hypothetical protein STM0277
3SNSL254_A0305320859..321344 [+], 486194443822hemolysin-coregulated protein SciK
4SNSL254_A33823280307..3280792 [-], 486194445288hypothetical protein Hcp
5SNSL254_A25642485885..2486253 [+], 369194445297hypothetical protein STY2606

Download FASTA format files
Proteins        Genes

Homology Immunity protein list
STM0278, STY0301, STY2607

Immunity protein identified
#Locus tag(Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1SNSL254_A0304320384..320716 [+], 333194443478hypothetical protein STM0278
2SNSL254_A0301318413..318838 [+], 426194444424hypothetical protein STY0301
3SNSL254_A25652486253..2486771 [+], 519194444744hypothetical protein STY2607

Download FASTA format files
Proteins        Genes
(1) Blondel CJ et al. (2009). Comparative genomic analysis uncovers 3 novel loci encoding type six secretion systems differentially distributed in Salmonella serotypes. BMC Genomics. 10:354. [PudMed:19653904] in_silico
 
in_silico This literature contains bioinformatics investigation