SecReT6
I. Summary
SecReT6 ID325 insolico
StrainPseudomonas aeruginosa LESB58
Repliconchromosome [Browse all T6SS(s) in this replicon]
AccessionNC_011770
Location3218919..3238805
Comment
FunctionN/A
T6SS TypeType i; subtype i4a
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
ComponentTssHTssDTssLTssITssATssBTssCTssETssF
Number111111111
ComponentTssGTssJTssKTssM
Number1011
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III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1PLES_292513215630..3216904 [-], 1275218891647putative ABC-type transport protein, periplasmic component 
2PLES_292613217036..3217677 [-], 642218891648putative transcriptional regulator 
3PLES_292713217954..3218349 [+], 396218891649hypothetical protein 
4PLES_292813218372..3218908 [-], 537218891650hypothetical protein 
5PLES_292913218919..3220925 [-], 2007218891651hypothetical protein  TssI
6PLES_293013220962..3221960 [-], 999218891652hypothetical protein 
7PLES_293113222068..3222601 [-], 534218891653hypothetical protein 
8PLES_293213222675..3225224 [-], 2550218891654putative ClpA/B-type protease  TssH
9PLES_293313225226..3226242 [-], 1017218891655hypothetical protein  TssG
10PLES_293413226206..3227999 [-], 1794218891656hypothetical protein  TssF
11PLES_293513227983..3228408 [-], 426218891657hypothetical protein  TssE
12PLES_293613228421..3228918 [-], 498218891658hypothetical protein  TssD
13PLES_293713228992..3230476 [-], 1485218891659hypothetical protein  TssC
14PLES_293813230499..3231044 [-], 546218891660hypothetical protein  TssB
15PLES_293913231253..3231729 [+], 477218891661hypothetical protein 
16PLES_294013231789..3233120 [+], 1332218891662hypothetical protein  TssK
17PLES_294113233138..3233896 [+], 759218891663hypothetical protein  TssL
18PLES_294213233893..3237708 [+], 3816218891664hypothetical protein  TssM
19PLES_294313237705..3238805 [+], 1101218891665hypothetical protein  TssA
20PLES_294413238915..3240000 [+], 1086218891666putative transcriptional regulator  Sfa3
21PLES_294513240113..3240502 [+], 390218891667hypothetical protein 
22PLES_29461 (msuE)3240662..3241222 [+], 561218891668NADH-dependent FMN reductase MsuE 
23PLES_29471 (msuD)3241232..3242377 [+], 1146218891669methanesulfonate sulfonatase MsuD 
24PLES_294813242407..3243591 [+], 1185218891670putative FMNH2-dependent monooxygenase 
 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.
 






2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.
 






3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.
 







Homology Effector list
PA5089

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1PLES_547916061914..6064151 [-], 2238218894188hypothetical protein PA5089

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Proteins        Genes

Homology Immunity protein list
PA5086, PA5088, PA5087

Immunity protein identified
#Locus tag(Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1PLES_547616059279..6059920 [-], 642218894185hypothetical protein PA5086
2PLES_547716060157..6060978 [-], 822218894186hypothetical protein PA5088
3PLES_547816061035..6061910 [-], 876218894187hypothetical protein PA5087

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Proteins        Genes
(1) Barret M et al. (2011). Genomic analysis of the type VI secretion systems in Pseudomonas spp.: novel clusters and putative effectors uncovered. Microbiology. 157(Pt 6):1726-39. [PudMed:21474537] in_silico
 
in_silico This literature contains bioinformatics investigation