SecReT6
I. Summary
SecReT6 ID387 insolico
StrainErwinia amylovora CFBP1430
Repliconchromosome [Browse all T6SS(s) in this replicon]
AccessionNC_013961
Location3291637..3325348
Comment
FunctionN/A
T6SS TypeType i; subtype i2
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
ComponentTssHTssDTssLTssITssATssBTssCTssETssF
Number111421111
ComponentTssGTssJTssKTssM
Number1211
Click the above image to have a larger view
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1EAMY_3197 (nikS)3288300..3289466 [-], 1167292489660carbamoyl-phosphate synthase large subunit 
2EAMY_31983290401..3290670 [-], 270292489661hypothetical protein 
3EAMY_31993291119..3291307 [-], 189292489662plasmid-like protein 
4EAMY_32003291366..3291587 [-], 222292489663hypothetical protein 
5EAMY_32013291637..3293037 [-], 1401292489664type VI secretion system core protein  TssA
6EAMY_32023293082..3293534 [-], 453292489665type VI secretion system core protein  TssE
7EAMY_32033294088..3294261 [+], 174292489666hypothetical protein 
8EAMY_32043294266..3295156 [-], 891292489667hypothetical protein  TssI
9EAMY_32053295172..3295267 [+], 96292489668hypothetical protein 
10EAMY_32063295981..3296565 [-], 585292489669hypothetical protein  TssI
11EAMY_32073296570..3296995 [-], 426292489670hypothetical protein  TssJ
12EAMY_32083297099..3297842 [-], 744292489671hypothetical protein 
13EAMY_32093299044..3299826 [-], 783292489672hypothetical protein 
14EAMY_32103299826..3300380 [-], 555292489673hypothetical protein 
15EAMY_32113300382..3302694 [-], 2313292489674type VI secretion system effector protein VgrG  TssI
16EAMY_32123302699..3303223 [-], 525292489675type VI secretion system core protein  TssJ
17EAMY_32133303249..3304331 [-], 1083292489676type VI secretion system core protein  TssG
18EAMY_32143304295..3306064 [-], 1770292489677type VI secretion system core protein  TssF
19EAMY_32153306219..3307826 [-], 1608292489678type VI secretion system core protein  TssA
20EAMY_32163307823..3311194 [-], 3372292489679type VI secretion system core protein  TssM
21EAMY_32173311187..3312395 [-], 1209292489680hypothetical protein 
22EAMY_32183312398..3312667 [-], 270292489681hypothetical protein  PAAR
23EAMY_32193312806..3313345 [-], 540292489682hypothetical protein 
24EAMY_32203313420..3315777 [-], 2358292489683type VI secretion system effector protein VgrG  TssI
25EAMY_32213315923..3316132 [-], 210292489684hypothetical protein 
26EAMY_3222 (clpV3)3316218..3318878 [-], 2661292489685type VI secretion system core protein ATPase  TssH
27EAMY_3223 (hcp)3319049..3319540 [-], 492292489686type VI secretion system effector protein hcp  TssD
28EAMY_32243319573..3321228 [-], 1656292489687type VI secretion system-associated protein  TagL
29EAMY_32253321228..3321905 [-], 678292489688type VI secretion system-associated protein  TssL
30EAMY_32263321902..3323251 [-], 1350292489689type VI secretion system core protein  TssK
31EAMY_32273323269..3324816 [-], 1548292489690type VI secretion system core protein  TssC
32EAMY_32283324851..3325348 [-], 498292489691type VI secretion system core protein  TssB
33EAMY_32293325818..3325997 [+], 180292489692hypothetical protein 
34EAMY_32303325977..3326078 [-], 102292489693hypothetical protein 
 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

Download FASTA format files
Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.
 






2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.
 






3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.
 







Homology Effector list
EC042_4529

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1EAMY_3223(hcp)3319049..3319540 [-], 492292489686type VI secretion system effector protein hcp EC042_4529

Download FASTA format files
Proteins        Genes
N/A
(1) Mann RA et al. (2013). Comparative genomics of 12 strains of Erwinia amylovora identifies a pan-genome with a large conserved core. PLoS One. 8(2):e55644. [PudMed:23409014] in_silico
(2) De Maayer P et al. (2011). Comparative genomics of the Type VI secretion systems of Pantoea and Erwinia species reveals the presence of putative effector islands that may be translocated by the VgrG and Hcp proteins. BMC Genomics. 12:576. [PudMed:22115407] in_silico
 
in_silico This literature contains bioinformatics investigation