SecReT6
I. Summary
SecReT6 ID482 insolico
StrainPseudomonas fluorescens SBW25
Repliconchromosome [Browse all T6SS(s) in this replicon]
AccessionNC_012660
Location6570496..6590839
Comment
FunctionN/A
T6SS TypeType i; subtype i3
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
ComponentTssHTssDTssLTssITssATssBTssCTssETssF
Number111111111
ComponentTssGTssJTssKTssM
Number1111
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III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1PFLU60106566154..6569129 [-], 2976229593375putative serine/threonine protein kinase  PpkA
2PFLU60116569126..6569845 [-], 720229593376putative phosphatase  PppA
3PFLU60126569846..6570499 [-], 654229593377hypothetical protein  TagF
4PFLU60136570496..6573996 [-], 3501229593378hypothetical protein  TssM
5PFLU60146573993..6575282 [-], 1290229593379hypothetical protein  TssL
6PFLU60156575289..6576623 [-], 1335229593380hypothetical protein  TssK
7PFLU60166576642..6577151 [-], 510229593381putative lipoprotein  TssJ
8PFLU60176577209..6578546 [-], 1338229593382hypothetical protein  Fha
9PFLU60186578939..6579958 [+], 1020229593383hypothetical protein  TssA
10PFLU60196580013..6580519 [+], 507229593384hypothetical protein  TssB
11PFLU60206580522..6582021 [+], 1500229593385hypothetical protein  TssC
12PFLU60216582126..6582614 [+], 489229593386hypothetical protein  TssD
13PFLU60226582708..6583223 [+], 516229593387hypothetical protein  TssE
14PFLU60236583220..6585079 [+], 1860229593388hypothetical protein  TssF
15PFLU60246585043..6586086 [+], 1044229593389hypothetical protein  TssG
16PFLU6025 (clpB2)6586079..6588742 [+], 2664229593390chaperone  TssH
17PFLU60266588899..6590839 [+], 1941229593391hypothetical protein  TssI
18PFLU60276590855..6591289 [+], 435229593392hypothetical protein 
19PFLU60286591302..6595732 [+], 4431229593393hypothetical protein  PAAR
 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.
 






2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.
 






3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.
 







Homology Effector list
PA0085 , PA0091

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1PFLU60216582126..6582614 [+], 489229593386hypothetical protein PA0085
2PFLU60266588899..6590839 [+], 1941229593391hypothetical protein PA0091

Download FASTA format files
Proteins        Genes
N/A
Regulatory element identified
GacS
RegulatorDescriptionReference
GacS (PFLU3777)ActivatorPMID: 23864577

(1) Cheng X, et al. (2013). The Gac regulon of Pseudomonas fluorescens SBW25. Environ Microbiol Rep. 5(4):608-19. [PudMed:23864577] experimental
(2) Barret M et al. (2011). Genomic analysis of the type VI secretion systems in Pseudomonas spp.: novel clusters and putative effectors uncovered. Microbiology. 157(Pt 6):1726-39. [PudMed:21474537] in_silico
 
experimental This literature contains experimental investigation
in_silico This literature contains bioinformatics investigation