SecReT6
I. Summary
SecReT6 ID489 insolico
StrainBurkholderia pseudomallei MSHR346
Repliconchromosome I [Browse all T6SS(s) in this replicon]
AccessionNC_012695
Location3659169..3679155
Comment
FunctionN/A
T6SS TypeType i; subtype i4b
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
ComponentTssHTssDTssLTssITssATssBTssCTssETssF
Number111011111
ComponentTssGTssJTssKTssM
Number1111
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III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1GBP346_A37943655294..3656742 [+], 1449237814010type I secretion outer membrane protein, TolC family 
2GBP346_A37953656727..3656876 [+], 150237814011hypothetical protein 
3GBP346_A37963656952..3657920 [-], 969237814012hypothetical protein 
4GBP346_A37973657932..3658897 [+], 966237814013D-alanyl-D-alanine carboxypeptidase family protein 
5GBP346_A37983658926..3659063 [+], 138237814014hypothetical protein 
6GBP346_A37993659048..3659161 [+], 114237814015hypothetical protein 
7GBP346_A3800 (icmF_1)3659169..3663062 [+], 3894237814016type VI secretion protein IcmF  TssM
8GBP346_A38013663059..3664048 [+], 990237814017type VI secretion-associated protein, family 
9GBP346_A38023664053..3664985 [+], 933237814018OmpA family protein  TagL
10GBP346_A38033665184..3666305 [-], 1122237814019type VI secretion-associated protein, ImpA family  TssA
11GBP346_A3804 (clpV_1)3666395..3669064 [-], 2670237814020type VI secretion ATPase, ClpV1 family  TssH
12GBP346_A38053669098..3670198 [-], 1101237814021type VI secretion protein, VC_A0110 family  TssG
13GBP346_A3806 (vasA_3)3670162..3672000 [-], 1839237814022type VI secretion protein, VC_A0110 family  TssF
14GBP346_A38073672079..3672561 [-], 483237814023type VI secretion system lysozyme-related protein  TssE
15GBP346_A38083672619..3673122 [-], 504237814024type VI secretion system effector, Hcp1 family  TssD
16GBP346_A38093673195..3674685 [-], 1491237814025type VI secretion protein, EvpB/family  TssC
17GBP346_A38103674702..3675220 [-], 519237814026type VI secretion protein, VC_A0110 family  TssB
18GBP346_A38113675257..3675892 [-], 636237814027hypothetical protein 
19GBP346_A38123675986..3676315 [-], 330237814028hypothetical protein 
20GBP346_A38133676316..3676918 [+], 603237814029type VI secretion lipoprotein, family  TssJ
21GBP346_A38143676967..3678373 [+], 1407237814030type VI secretion protein, VC_A0110 family  TssK
22GBP346_A38153678370..3679155 [+], 786237814031type IV / VI secretion system protein, DotU family  TssL
23GBP346_A38163679257..3679622 [+], 366237814032phage tail completion protein 
24GBP346_A38173680712..3681128 [-], 417237814033DNA (cytosine-5-)-methyltransferase 
25GBP346_A38183681213..3681626 [-], 414237814034phage tail protein I 
26GBP346_A38193681619..3681945 [-], 327237814035gp37, bacteriophage baseplate assembly protein J 
27GBP346_A38203682549..3682722 [+], 174237814036hypothetical protein 
28GBP346_A38213682719..3682838 [+], 120237814037hypothetical protein 
29GBP346_A38223683781..3683918 [+], 138237814038hypothetical protein 
 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.
 






2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.
 






3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.
 







Homology Effector list
BTH_I2705 , BTH_I2698, BTH_I2697, BTH_I2693, BTH_I2691, BCAL0343, BTH_I0068

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1GBP346_A16211557437..1560244 [+], 2808237811881Rhs element Vgr protein BTH_I2705
2GBP346_A16251562361..1564769 [+], 2409237811885hypothetical protein BTH_I2698
3GBP346_A16261564878..1568213 [+], 3336237811886Rhs element Vgr protein BTH_I2697
4GBP346_A16311570357..1573191 [+], 2835237811891Rhs element Vgr protein BTH_I2693
5GBP346_A16331574214..1577237 [+], 3024237811893hypothetical protein BTH_I2691
6GBP346_A38083672619..3673122 [-], 504237814024type VI secretion system effector, Hcp1 family BCAL0343
7GBP346_A42674087321..4088286 [+], 966237814469hypothetical protein BTH_I0068

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Proteins        Genes

Homology Immunity protein list
BTH_I2700, BTH_I0069

Immunity protein identified
#Locus tag(Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1GBP346_A16231561217..1561774 [+], 558237811883hypothetical protein BTH_I2700
2GBP346_A42684088273..4088641 [+], 369237814470putative lipoprotein BTH_I0069

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Proteins        Genes
N/A