SecReT6
I. Summary
SecReT6 ID513 insolico
StrainVibrio cholerae O1 str. 2010EL-1786
Repliconchromosome II [Browse all T6SS(s) in this replicon]
AccessionNC_016446
Location889678..913466
Comment
FunctionN/A
T6SS TypeType i; subtype i1
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
ComponentTssHTssDTssLTssITssATssBTssCTssETssF
Number101121111
ComponentTssGTssJTssKTssM
Number1111
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III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1Vch1786_II0899885523..887235 [-], 1713360038109ribosomal large subunit pseudouridine synthase A 
2Vch1786_II0900888203..889246 [+], 1044360038110hypothetical protein 
3Vch1786_II0901889678..890184 [+], 507360038111type VI secretion system protein ImpB  TssB
4Vch1786_II0902890225..891703 [+], 1479360038112type VI secretion system protein ImpC  TssC
5Vch1786_II0903891706..892143 [+], 438360038113type VI secretion system protein  TssE
6Vch1786_II0904892149..893918 [+], 1770360038114type VI secretion system protein ImpG  TssF
7Vch1786_II0905893882..894898 [+], 1017360038115type VI secretion system protein ImpH  TssG
8Vch1786_II0906894901..896388 [+], 1488360038116type VI secretion system protein ImpI  Fha
9Vch1786_II0907896391..896867 [+], 477360038117type VI secretion system protein VasD  TssJ
10Vch1786_II0908896874..898208 [+], 1335360038118type VI secretion system protein ImpJ  TssK
11Vch1786_II0909898211..898984 [+], 774360038119type VI secretion system protein ImpK  TssL
12Vch1786_II0910899010..901619 [+], 2610360038120type VI secretion system protein VasG  TssH
13Vch1786_II0911901622..903214 [+], 1593360038121sigma-54 dependent transcriptional regulator  VasH
14Vch1786_II0912903211..903867 [+], 657360038122type VI secretion system protein VasI  VCA0118
15Vch1786_II0913903877..905286 [+], 1410360038123type VI secretion system protein VasJ  TssA
16Vch1786_II0914905302..908847 [+], 3546360038124type VI secretion system protein ImpL  TssM
17Vch1786_II0915908898..910160 [+], 1263360038125type VI secretion system protein VasL  TssA
18Vch1786_II0916910413..913466 [+], 3054360038126VgrG protein  TssI
19Vch1786_II0917913463..913831 [+], 369360038127hypothetical protein  TsiV3 (i)
20Vch1786_II0919913979..914239 [-], 261360038129hypothetical protein 
21Vch1786_II0918914214..914423 [+], 210360038128hypothetical protein 
22Vch1786_II0920 (rbsD)914523..914942 [+], 420360038130D-ribose pyranase 
23Vch1786_II0921 (rbsA)914969..916471 [+], 1503360038131D-ribose transporter ATP binding protein 
24Vch1786_II0922 (rbsC)916486..917469 [+], 984360038132ribose ABC transporter permease protein 
25Vch1786_II0923 (rbsB)917530..918408 [+], 879360038133D-ribose transporter subunit RbsB 
 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.
 






2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.
 






3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.
 







Homology Effector list
VCA0017 , VC1416, VC1418, VCA0285, VCA0017, VCA0018, VCA0020, VCA0118, VCA0123

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1Vch1786_I0914(hcp)986816..987145 [+], 330360035309hcp protein VCA0017
2Vch1786_I0915987273..990764 [+], 3492360035310type VI secretion system secreted protein VgrG VC1416
3Vch1786_I0917991606..993531 [+], 1926360035312hypothetical protein VC1418
4Vch1786_II003131645..32316 [+], 672360037245hypothetical protein VCA0285
5Vch1786_II0813(hcp-1)792614..793132 [+], 519360038023hcp protein VCA0017
6Vch1786_II0814793260..795344 [+], 2085360038024type VI secretion system secreted protein VgrG VCA0018
7Vch1786_II0816796228..799485 [+], 3258360038026hypothetical protein VCA0020
8Vch1786_II0912903211..903867 [+], 657360038122type VI secretion system protein VasI VCA0118
9Vch1786_II0916910413..913466 [+], 3054360038126VgrG protein VCA0123

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Proteins        Genes

Homology Immunity protein list
VC1419, VCA0286, VCA0021, VCA0124

Immunity protein identified
#Locus tag(Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1Vch1786_I0918993528..994271 [+], 744360035313hypothetical protein VC1419
2Vch1786_II003232318..32668 [+], 351360037246hypothetical protein VCA0286
3Vch1786_II0817799486..800214 [+], 729360038027hypothetical protein VCA0021
4Vch1786_II0917913463..913831 [+], 369360038127hypothetical protein VCA0124

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Proteins        Genes
N/A