SecReT6
I. Summary
SecReT6 ID56 insolico
StrainYersinia pestis biovar Microtus str. 91001
Repliconchromosome [Browse all T6SS(s) in this replicon]
AccessionNC_005810
Location1480241..1524047
Comment
FunctionN/A
T6SS TypeType i; subtype i2
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
ComponentTssHTssDTssLTssITssATssBTssCTssETssF
Number111111111
ComponentTssGTssJTssKTssM
Number1111
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III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1YP_13451475925..1476245 [+], 32145441171hypothetical protein 
2YP_1346 (fabZ1)1476509..1477033 [+], 52545441172myristoyl-acyl carrier dehydratase 
3YP_1347 (fabF3)1477023..1478306 [+], 1284454411733-ketoacyl-ACP synthase 
4YP_1348 (fabG6)1478254..1479045 [+], 792454411743-ketoacyl-ACP reductase 
5YP_1349 (pksG)1479061..1480299 [+], 123945441175hydroxymethylglutaryl-coenzyme A synthase 
6YP_1350 (caiD1)1480241..1481011 [+], 77145441176enoyl-CoA hydratase 
7YP_1351 (caiD2)1480989..1481765 [+], 77745441177polyketide biosynthesis enoyl-CoA hydratase 
8YP_1352 (fabG7)1481768..1482556 [+], 78945441178short chain dehydrogenase 
9YP_13531482595..1483083 [+], 48945441179hypothetical protein 
10YP_1354 (acpP1)1483121..1483369 [+], 24945441180acyl carrier protein 
11YP_1355 (fabD1)1483468..1484316 [+], 84945441181acyl transferase 
12YP_13561485302..1485805 [+], 50445441182hypothetical protein  TssB
13YP_13571485848..1487392 [+], 154545441183hypothetical protein  TssC
14YP_13581487404..1488756 [+], 135345441184hypothetical protein  TssK
15YP_13591488753..1489439 [+], 68745441185hypothetical protein  TssL
16YP_1360 (ompA2)1489439..1491175 [+], 173745441186hypothetical protein  TagL
17YP_1361 (hcp3)1491179..1491670 [+], 49245441187hemolysin-coregulated protein  TssD
18YP_1362 (clpA2)1492058..1494700 [+], 264345441188ATPase subunit of ATP-dependent protease  TssH
19YP_1363 (vgrG1)1494703..1497051 [+], 234945441189hypothetical protein  TssI
20YP_13641497067..1499367 [+], 230145441190hypothetical protein 
21YP_1365 (uvrA2)1499364..1500137 [+], 77445441191hypothetical protein 
22YP_1366 (mdlB3)1500291..1500551 [+], 26145441192ABC-type multidrug/protein/lipid transport system, ATPase 
23YP_13671500567..1502750 [+], 218445441193hypothetical protein 
24YP_13681502923..1503393 [+], 47145441194hypothetical protein 
25YP_13691504126..1504446 [-], 32145441195transposase 
26YP_13701505669..1506790 [+], 112245441196hypothetical protein 
27YP_1371 (icmF1)1506787..1510209 [+], 342345441197hypothetical protein  TssM
28YP_13731511844..1512929 [+], 108645441198hypothetical protein  PAAR
29YP_13741512929..1513399 [+], 47145441199hypothetical protein 
30YP_13751513620..1515383 [+], 176445441200hypothetical protein  TssF
31YP_13761515347..1516432 [+], 108645441201hypothetical protein  TssG
32YP_13771516407..1516988 [+], 58245441202hypothetical protein  TssJ
33YP_13781516988..1517440 [+], 45345441203hypothetical protein  TssE
34YP_13791517465..1518832 [+], 136845441204hypothetical protein  TssA
35YP_13801519044..1519667 [-], 62445441205hypothetical protein 
36YP_1381 (uup3)1520182..1521945 [+], 176445441206ABC transporter ATP-binding protein 
37YP_13821522173..1522817 [+], 64545441207hypothetical protein 
38YP_13831522839..1524047 [-], 120945441208transposase for the IS285 insertion element 
39YP_1384 (moeB)1524214..1525014 [-], 80145441209molybdopterin biosynthesis protein MoeB 
40YP_1385 (moeA)1524986..1526260 [-], 127545441210molybdopterin biosynthesis protein MoeA 
41YP_1386 (aslB1)1526795..1528105 [-], 131145441211heme-binding protein 
42YP_1387 (phnL3)1528115..1528783 [-], 66945441212ABC transporter ATP-binding protein 
 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.
 






2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.
 






3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.
 







Homology Effector list
EC042_4529

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1YP_1361(hcp3)1491179..1491670 [+], 49245441187hemolysin-coregulated protein EC042_4529

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Proteins        Genes
N/A
(1) Boyer F et al. (2009). Dissecting the bacterial type VI secretion system by a genome wide in silico analysis: what can be learned from available microbial genomic resources. BMC Genomics. 10:104. [PudMed:19284603] in_silico
 
in_silico This literature contains bioinformatics investigation