SecReT6
I. Summary
SecReT6 ID596 insolico
StrainVibrio cholerae LMA3984-4
Repliconchromosome II [Browse all T6SS(s) in this replicon]
AccessionNC_017269
Location114221..137457
Comment
FunctionN/A
T6SS TypeType i; subtype i1
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
ComponentTssHTssDTssLTssITssATssBTssCTssETssF
Number101121111
ComponentTssGTssJTssKTssM
Number1111
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III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1VCLMA_B0092110066..111745 [-], 1680384422624Pseudouridylate synthase, 23S RNA-specific 
2VCLMA_B0093112517..112801 [+], 285384422625Uropathogenic specific protein  PAAR
3VCLMA_B0094112869..113789 [+], 921384422626hypothetical protein 
4VCLMA_B0095114221..114727 [+], 507384422627hypothetical protein  TssB
5VCLMA_B0096114771..116246 [+], 1476384422628hypothetical protein  TssC
6VCLMA_B0097116249..116686 [+], 438384422629hypothetical protein  TssE
7VCLMA_B0098116692..118461 [+], 1770384422630protein ImpG/VasA  TssF
8VCLMA_B0099118647..119441 [+], 795384422631protein ImpH/VasB  TssG
9VCLMA_B0100119444..120931 [+], 1488384422632protein ImpI/VasC  Fha
10VCLMA_B0101120934..121410 [+], 477384422633Type VI secretion lipoprotein/VasD  TssJ
11VCLMA_B0102121417..122751 [+], 1335384422634hypothetical protein  TssK
12VCLMA_B0103122754..123527 [+], 774384422635Outer membrane protein ImpK/VasF, OmpA/MotB domain protein  TssL
13VCLMA_B0104123553..126162 [+], 2610384422636ClpB protein  TssH
14VCLMA_B0105126165..127757 [+], 1593384422637Sigma-54 dependent transcriptional regulator  VasH
15VCLMA_B0106127754..128410 [+], 657384422638Type VI secretion protein VasI  VCA0118
16VCLMA_B0107128420..129829 [+], 1410384422639hypothetical protein  TssA
17VCLMA_B0108129845..133390 [+], 3546384422640IcmF-like protein  TssM
18VCLMA_B0109133441..134706 [+], 1266384422641Type VI secretion-like protein VasL  TssA
19VCLMA_B0110134938..137457 [+], 2520384422642VgrG-3 protein  TssI
20VCLMA_B0111138764..139024 [-], 261384422643hypothetical protein 
21VCLMA_B0112139308..139727 [+], 420384422644ribose ABC transporter high affinity permease RbsD 
22VCLMA_B0113139754..141256 [+], 1503384422645ribose ABC transporter ATP-binding protein RbsA 
23VCLMA_B0114141271..142251 [+], 981384422646ribose ABC transporter permease RbsC 
 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.
 






2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.
 






3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.
 







Homology Effector list
VCA0020 , VCA0118, VCA0123, VCA0017

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1VCLMA_B001721049..24309 [+], 3261384422552membrane protein VCA0020
2VCLMA_B0106127754..128410 [+], 657384422638Type VI secretion protein VasI VCA0118
3VCLMA_B0110134938..137457 [+], 2520384422642VgrG-3 protein VCA0123
4VCLMA_A12461410747..1411265 [+], 519384424527hypothetical protein VCA0017

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Proteins        Genes

Homology Immunity protein list
VCA0021

Immunity protein identified
#Locus tag(Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1VCLMA_B001824310..24864 [+], 555384422553hypothetical protein VCA0021

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Proteins        Genes
N/A