I. Summary
SecReT6 ID622 insolico
StrainEscherichia coli IHE3034
Repliconchromosome [Browse all T6SS(s) in this replicon]
T6SS TypeType i; subtype i1
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
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III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1ECOK1_0214 (gloB)238911..239666 [-], 756386597956hydroxyacylglutathione hydrolase 
2ECOK1_0216239700..240422 [+], 723386597957putative methyltransferase 
3ECOK1_0215 (rnhA)240419..240886 [-], 468386597958ribonuclease H 
4ECOK1_0217 (dnaQ)240951..241682 [+], 732386597959DNA polymerase III subunit epsilon 
5ECOK1_0219242023..242166 [+], 144386597960hypothetical protein 
6ECOK1_0220242220..243005 [+], 786386597961putative lipoprotein 
7ECOK1_0221243345..243824 [-], 480386597962hypothetical protein  TssD
8ECOK1_0222243842..245200 [-], 1359386597963ImpA domain-containing protein  TssA
9ECOK1_0223245211..248678 [-], 3468386597964hypothetical protein  TssM
10ECOK1_0224248758..250200 [-], 1443386597965hypothetical protein  TssA
11ECOK1_0225250205..250948 [-], 744386597966hypothetical protein 
12ECOK1_0226 (clpB)250945..253704 [-], 2760386597967ATP-dependent chaperone protein ClpB  TssH
13ECOK1_0227253714..254478 [-], 765386597968hypothetical protein  TssL
14ECOK1_0228254483..255829 [-], 1347386597969hypothetical protein  TssK
15ECOK1_0229255832..256356 [-], 525386597970type VI secretion lipoprotein  TssJ
16ECOK1_0230256353..257633 [-], 1281386597971hypothetical protein  Fha
17ECOK1_0231257650..258699 [-], 1050386597972hypothetical protein  TssG
18ECOK1_0232258663..260504 [-], 1842386597973hypothetical protein  TssF
19ECOK1_0233260510..260935 [-], 426386597974hypothetical protein  TssE
20ECOK1_0234260940..262424 [-], 1485386597975hypothetical protein  TssC
21ECOK1_0235262447..262950 [-], 504386597976hypothetical protein  TssB
22ECOK1_0236263656..264174 [+], 519386597977hypothetical protein  TssD
23ECOK1_0237264395..266377 [+], 1983386597978ImpA family type VI secretion-associated protein  TssI
24ECOK1_0238266484..267530 [+], 1047386597979hypothetical protein 
25ECOK1_0239267523..268962 [+], 1440386597980hypothetical protein  PAAR
26ECOK1_0241271075..271563 [+], 489386597981hypothetical protein 
27ECOK1_0242271834..272604 [-], 771386597982hydrolase 
28ECOK1_0243272758..273231 [+], 474386597983inhibitor of vertebrate lysozyme 
29ECOK1_0244 (fadE)273274..275718 [-], 2445386597984acyl-coenzyme A dehydrogenase 
30ECOK1_0245 (gmhA)275958..276536 [+], 579386597985phosphoheptose isomerase 
31ECOK1_0247276741..277508 [+], 768386597986putative glutamine amidotransferase, class-II 
32ECOK1_0246277479..278219 [-], 741386597987hypothetical protein 
33ECOK1_0248278476..278616 [-], 141386597988hypothetical protein 
34ECOK1_0249278543..279280 [+], 738386597989NlpC/P60 family protein 
35ECOK1_0250279456..279953 [+], 498386597990hypothetical protein 
36ECOK1_0251280036..280194 [-], 159386597991hypothetical protein 
37ECOK1_0252 (fhiA)280273..282012 [-], 1740386597992protein FhiA 
38ECOK1_0253281972..282742 [+], 771386597993putative chemotaxis protein  TagL
39ECOK1_0254 (dinB)282813..283868 [+], 1056386597994DNA polymerase IV 
40ECOK1_0255283920..284213 [+], 294386597995prevent-host-death family protein 
41ECOK1_0256284216..284614 [+], 399386597996hypothetical protein 
42ECOK1_0257284624..285076 [+], 453386597997GNAT family acetyltransferase 
43ECOK1_0258285254..286405 [+], 1152386597998RtcB protein 
44ECOK1_0259286402..287016 [+], 615386597999peptidyl-tRNA hydrolase domain-containing protein 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Homology Effector list

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1ECOK1_0236263656..264174 [+], 519386597977hypothetical protein ABG57132

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Proteins        Genes