SecReT6
I. Summary
SecReT6 ID626 insolico
StrainEscherichia coli UM146
Repliconchromosome [Browse all T6SS(s) in this replicon]
AccessionNC_017632
Location3334311..3373707
Comment
FunctionN/A
T6SS TypeType i; subtype i1
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
ComponentTssHTssDTssLTssITssATssBTssCTssETssF
Number121111111
ComponentTssGTssJTssKTssM
Number1111
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III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1UM146_16035 (prfH)3330037..3330651 [-], 615386605778peptide chain release factor-like protein 
2UM146_160403330648..3331787 [-], 1140386605779hypothetical protein 
3UM146_160453331977..3332429 [-], 453386605780hypothetical protein 
4UM146_160503332439..3332837 [-], 399386605781putative toxin YafO 
5UM146_160553332840..3333133 [-], 294386605782putative antitoxin of the YafO-YafN toxin-antitoxin system 
6UM146_160603333185..3334240 [-], 1056386605783DNA polymerase IV 
7UM146_160653334311..3335081 [-], 771386605784hypothetical protein  TagL
8UM146_160703335041..3336780 [+], 1740386605785flagellar system protein 
9UM146_160753337099..3337596 [-], 498386605786hypothetical protein 
10UM146_160803337772..3338530 [-], 759386605787putative exported hydrolase 
11UM146_160853338833..3339573 [+], 741386605788hypothetical protein 
12UM146_160903339544..3340311 [-], 768386605789putative glutamine amidotransferases class-II 
13UM146_16095 (gmhA)3340516..3341094 [-], 579386605790phosphoheptose isomerase 
14UM146_16100 (fadE)3341334..3343778 [+], 2445386605791acyl-CoA dehydrogenase 
15UM146_161053343821..3344294 [-], 474386605792C-lysozyme inhibitor 
16UM146_161103344448..3345218 [+], 771386605793hypothetical protein 
17UM146_161153345489..3346001 [-], 513386605794hypothetical protein 
18UM146_161203346071..3346574 [-], 504386605795hypothetical protein 
19UM146_161253346803..3347288 [-], 486386605796putative transposase 
20UM146_161303347388..3347567 [-], 180386605797putative H-repeat associated protein 
21UM146_161353347825..3348115 [-], 291386605798hypothetical protein 
22UM146_161403348090..3349154 [-], 1065386605799hypothetical protein 
23UM146_161453349522..3350568 [-], 1047386605800hypothetical protein 
24UM146_161503350675..3352657 [-], 1983386605801hypothetical protein  TssI
25UM146_161553352673..3352783 [-], 111386605802hypothetical protein 
26UM146_161603352878..3353396 [-], 519386605803hypothetical protein  TssD
27UM146_161653354102..3354605 [+], 504386605804type VI secretion protein  TssB
28UM146_161703354628..3356112 [+], 1485386605805type VI secretion protein EvpB  TssC
29UM146_161753356117..3356542 [+], 426386605806type VI secretion system lysozyme-like protein  TssE
30UM146_161803356548..3358389 [+], 1842386605807hypothetical protein  TssF
31UM146_161853358353..3359402 [+], 1050386605808hypothetical protein  TssG
32UM146_161903359407..3360699 [+], 1293386605809hypothetical protein  Fha
33UM146_161953360696..3361220 [+], 525386605810hypothetical protein  TssJ
34UM146_162003361223..3362569 [+], 1347386605811type VI secretion protein  TssK
35UM146_162053362574..3363338 [+], 765386605812hypothetical protein  TssL
36UM146_162103363348..3366107 [+], 2760386605813putative ATPase with chaperone activity  TssH
37UM146_162153366104..3366847 [+], 744386605814type VI secretion-associated protein 
38UM146_162203366852..3368294 [+], 1443386605815hypothetical protein  TssA
39UM146_162253368314..3371841 [+], 3528386605816hypothetical protein  TssM
40UM146_162403373228..3373707 [+], 480386605817hypothetical protein  TssD
41UM146_162453374047..3374832 [-], 786386605818putative aminopeptidase 
42UM146_162503375370..3376110 [-], 741386605819DNA polymerase III subunit epsilon 
43UM146_16255 (rnhA)3376166..3376633 [+], 468386605820ribonuclease H 
44UM146_162603376630..3377352 [-], 723386605821putative methyltransferase 
45UM146_162653377386..3378141 [+], 756386605822hydroxyacylglutathione hydrolase 
46UM146_16270 (mltD)3378213..3378581 [+], 369386605823membrane-bound lytic murein transglycosylase D 
 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.
 






2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.
 






3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.
 







Homology Effector list
ABG57132

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1UM146_161603352878..3353396 [-], 519386605803hypothetical protein ABG57132

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Proteins        Genes
N/A
N/A