SecReT6
I. Summary
SecReT6 ID627 insolico
StrainEscherichia coli O83:H1 str. NRG 857C
Repliconchromosome [Browse all T6SS(s) in this replicon]
AccessionNC_017634
Location242739..282235
Comment
FunctionN/A
T6SS TypeType i; subtype i1
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
ComponentTssHTssDTssLTssITssATssBTssCTssETssF
Number121121111
ComponentTssGTssJTssKTssM
Number1111
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III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1NRG857_01055238304..239059 [-], 756387615554hydroxyacylglutathione hydrolase 
2NRG857_01060239093..239815 [+], 723387615555putative S-adenosyl-L-methionine-dependent methyltransferase 
3NRG857_01065 (rnhA)239812..240279 [-], 468387615556ribonuclease H 
4NRG857_01070240344..241075 [+], 732387615557DNA polymerase III subunit epsilon 
5NRG857_01075241614..242399 [+], 786387615558putative aminopeptidase 
6NRG857_01080242739..243218 [-], 480387615559hypothetical protein  TssD
7NRG857_01085243236..244594 [-], 1359387615560hypothetical protein  TssA
8NRG857_01090244605..248129 [-], 3525387615561IcmF-like protein  TssM
9NRG857_01095248149..249591 [-], 1443387615562hypothetical protein  TssA
10NRG857_01100249596..250339 [-], 744387615563hypothetical protein 
11NRG857_01105250336..253098 [-], 2763387615564putative ATP-dependent Clp proteinase Aec27 ATP-binding chain, with chaperone activity  TssH
12NRG857_01110253108..253872 [-], 765387615565hypothetical protein  TssL
13NRG857_01115253877..255223 [-], 1347387615566hypothetical protein  TssK
14NRG857_01120255226..255750 [-], 525387615567hypothetical protein  TssJ
15NRG857_01125255747..257039 [-], 1293387615568hypothetical protein  Fha
16NRG857_01130257044..258093 [-], 1050387615569hypothetical protein  TssG
17NRG857_01135258057..259898 [-], 1842387615570hypothetical protein  TssF
18NRG857_01140259904..260329 [-], 426387615571hypothetical protein  TssE
19NRG857_01145260334..261818 [-], 1485387615572hypothetical protein  TssC
20NRG857_01150261841..262344 [-], 504387615573hypothetical protein  TssB
21NRG857_01155263050..263568 [+], 519387615574hypothetical protein  TssD
22NRG857_01160263663..263773 [+], 111387615575hypothetical protein 
23NRG857_01165263789..265771 [+], 1983387615576Vgr-like protein  TssI
24NRG857_01170265878..266273 [+], 396387615577hypothetical protein 
25NRG857_01180266918..268357 [+], 1440387615578hypothetical protein  PAAR
26NRG857_01185268332..268622 [+], 291387615579hypothetical protein 
27NRG857_01190268880..269059 [+], 180387615580putative H-repeat associated protein 
28NRG857_01195269159..269644 [+], 486387615581hypothetical protein 
29NRG857_01200269873..270376 [+], 504387615582hypothetical protein 
30NRG857_01205270446..270958 [+], 513387615583hypothetical protein 
31NRG857_01210271229..271999 [-], 771387615584hypothetical protein 
32NRG857_01215272153..272626 [+], 474387615585C-lysozyme inhibitor 
33NRG857_01220 (fadE)272669..275113 [-], 2445387615586acyl-CoA dehydrogenase 
34NRG857_01225 (gmhA)275353..275931 [+], 579387615587phosphoheptose isomerase 
35NRG857_01230276136..276903 [+], 768387615588putative amidotransfease 
36NRG857_01235276874..277614 [-], 741387615589hypothetical protein 
37NRG857_01240277917..278675 [+], 759387615590putative exported hydrolase 
38NRG857_01245278851..279348 [+], 498387615591hypothetical protein 
39NRG857_01250279766..281505 [-], 1740387615592flagellar system protein 
40NRG857_01255281465..282235 [+], 771387615593hypothetical protein  TagL
41NRG857_01260282306..283361 [+], 1056387615594DNA polymerase IV 
42NRG857_01265283413..283706 [+], 294387615595putative antitoxin of the YafO-YafN toxin-antitoxin system 
43NRG857_01270283709..284107 [+], 399387615596putative toxin YafO 
44NRG857_01275284117..284569 [+], 453387615597hypothetical protein 
45NRG857_01280284886..286025 [+], 1140387615598hypothetical protein 
46NRG857_01285 (prfH)286022..286636 [+], 615387615599peptide chain release factor-like protein 
 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.
 






2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.
 






3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.
 







Homology Effector list
ABG57132

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1NRG857_01155263050..263568 [+], 519387615574hypothetical protein ABG57132

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Proteins        Genes
N/A
N/A