I. Summary
SecReT6 ID631 insolico
StrainEscherichia coli UMNK88
Repliconchromosome [Browse all T6SS(s) in this replicon]
T6SS TypeType i; subtype i1
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
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III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1UMNK88_221237626..238366 [+], 741386612372hypothetical protein 
2UMNK88_220238363..238830 [-], 468386612373ribonuclease HI RnhA 
3UMNK88_222 (dnaQ)238895..239626 [+], 732386612374DNA polymerase III subunit epsilon 
4UMNK88_224240163..240948 [+], 786386612375lipoprotein YafT 
5UMNK88_225241574..242488 [-], 915386612376hypothetical protein 
6UMNK88_226242532..243014 [-], 483386612377hypothetical protein  TssD
7UMNK88_227243038..244390 [-], 1353386612378hypothetical protein  TssA
8UMNK88_228244401..247301 [-], 2901386612379type VI secretion protein IcmFhypothetical protein  TssM
9UMNK88_229247253..247861 [-], 609386612380type VI secretion protein IcmFhypothetical protein  TssM
10UMNK88_230247940..249352 [-], 1413386612381hypothetical protein  TssA
11UMNK88_231249357..250100 [-], 744386612382hypothetical protein 
12UMNK88_232 (clpB)250097..252862 [-], 2766386612383ATP-dependent chaperone protein ClpB  TssH
13UMNK88_233252871..253632 [-], 762386612384hypothetical protein  TssL
14UMNK88_234253637..254968 [-], 1332386612385hypothetical protein  TssK
15UMNK88_235254971..255495 [-], 525386612386hypothetical protein  TssJ
16UMNK88_236255492..256772 [-], 1281386612387hypothetical protein  Fha
17UMNK88_237256797..257879 [-], 1083386612388hypothetical protein  TssG
18UMNK88_238257843..259693 [-], 1851386612389hypothetical protein  TssF
19UMNK88_239259697..260110 [-], 414386612390hypothetical protein  TssE
20UMNK88_240260117..261592 [-], 1476386612391hypothetical protein  TssC
21UMNK88_241261643..261867 [-], 225386612392hypothetical protein  TssC
22UMNK88_242261902..262402 [-], 501386612393hypothetical protein  TssB
23UMNK88_243262828..262971 [+], 144386612394hypothetical protein 
24UMNK88_244263097..263615 [+], 519386612395hypothetical protein  TssD
25UMNK88_245263648..263785 [+], 138386612396hypothetical protein 
26UMNK88_246263825..264013 [+], 189386612397hypothetical protein 
27UMNK88_247264038..265966 [+], 1929386612398type IV secretion protein VgrG  TssI
28UMNK88_248266042..266836 [+], 795386612399core protein RhsA  PAAR
29UMNK88_249269376..270287 [+], 912386612400core protein RhsG 
30UMNK88_250270481..270657 [+], 177386612401hypothetical protein 
31UMNK88_251271088..272224 [+], 1137386612402insertion sequence transposase 
32UMNK88_252272265..273035 [-], 771386612403hypothetical protein 
33UMNK88_253273213..273662 [+], 450386612404C-lysozyme inhibitor YkeF 
34UMNK88_254273705..276185 [-], 2481386612405acyl coenzyme A dehydrogenase FadE 
35UMNK88_255 (gmhA)276389..276967 [+], 579386612406phosphoheptose isomerase 
36UMNK88_257277173..277940 [+], 768386612407amidotransferase YafJ 
37UMNK88_256277911..278651 [-], 741386612408hypothetical protein 
38UMNK88_258278807..279001 [-], 195386612409addiction module toxin protein YafQ 
39UMNK88_259279088..279348 [-], 261386612410antitoxin of YafQ-DinJ toxin-antitoxin system DinJ 
40UMNK88_261279534..280307 [+], 774386612411lipoprotein YafL 
41UMNK88_262280483..280980 [+], 498386612412hypothetical protein 
42UMNK88_263281204..282943 [-], 1740386612413flagellar biosynthesis protein FlhA 
43UMNK88_264282903..283673 [+], 771386612414lateral flagellar motor protein B LafU  TagL
44UMNK88_265283744..284799 [+], 1056386612415DNA polymerase IV DinB 
45UMNK88_266284851..285144 [+], 294386612416hypothetical protein 
46UMNK88_267285147..285545 [+], 399386612417hypothetical protein 
47UMNK88_268285633..286007 [+], 375386612418hypothetical protein 
48UMNK88_269286253..286507 [+], 255386612419hypothetical protein 
49UMNK88_270 (prfH)286476..286976 [+], 501386612420peptide chain release factor-like protein PrfH 
50UMNK88_271 (pepD)287033..288490 [-], 1458386612421aminoacyl-histidine dipeptidase PepD 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Homology Effector list

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1UMNK88_244263097..263615 [+], 519386612395hypothetical protein ABG57132

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Proteins        Genes