SecReT6
I. Summary
SecReT6 ID642 insolico
StrainBurkholderia pseudomallei 1026b
Repliconchromosome I [Browse all T6SS(s) in this replicon]
AccessionNC_017831
Location174161..194147
Comment
FunctionN/A
T6SS TypeType i; subtype i4b
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
ComponentTssHTssDTssLTssITssATssBTssCTssETssF
Number111011111
ComponentTssGTssJTssKTssM
Number1111
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III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1BP1026B_I0176170479..170598 [-], 120386860296hypothetical protein 
2BP1026B_I0177171372..171698 [+], 327386860297phage baseplate assembly protein 
3BP1026B_I0178171691..172104 [+], 414386860298phage tail protein I 
4BP1026B_I0179172122..172604 [+], 483386860299Phage-encoded modification methylase 
5BP1026B_I0180173084..173590 [+], 507386860300hypothetical protein 
6BP1026B_I0181173694..174059 [-], 366386860301phage tail completion protein 
7BP1026B_I0182 (tssL-1)174161..174946 [-], 786386860302type VI secretion system  TssL
8BP1026B_I0183 (tssK-1)174943..176289 [-], 1347386860303type VI secretion system  TssK
9BP1026B_I0184 (tssJ-1)176398..177051 [-], 654386860304type VI secretion system  TssJ
10BP1026B_I0185177020..177124 [-], 105386860305hypothetical protein 
11BP1026B_I0186 (tagM-1)177387..178058 [+], 672386860306lipoprotein 
12BP1026B_I0187 (tssB-1)178095..178613 [+], 519386860307type VI secretion system  TssB
13BP1026B_I0188 (tssC-1)178630..180120 [+], 1491386860308type VI secretion system  TssC
14BP1026B_I0189 (hcp-1)180175..180696 [+], 522386860309type VI secretion system  TssD
15BP1026B_I0190 (tssE-1)180754..181236 [+], 483386860310type VI secretion system  TssE
16BP1026B_I0191 (tssF-1)181316..183154 [+], 1839386860311type VI secretion system  TssF
17BP1026B_I0192 (tssG-1)183118..184218 [+], 1101386860312type VI secretion system  TssG
18BP1026B_I0193 (clpV-1)184252..186921 [+], 2670386860313type VI secretion system  TssH
19BP1026B_I0194 (tssA-1)187011..188132 [+], 1122386860314type VI secretion system  TssA
20BP1026B_I0195 (tagN-1)188331..189263 [-], 933386860315type VI secretion system  TagL
21BP1026B_I0196 (tagF-1)189268..190257 [-], 990386860316type VI secretion system 
22BP1026B_I0197 (tssM-1)190254..194147 [-], 3894386860317type VI secretion system  TssM
23BP1026B_I0198194419..194946 [-], 528386860318hypothetical protein 
24BP1026B_I0199195396..196364 [+], 969386860319hypothetical protein 
25BP1026B_I0200196574..197989 [-], 1416386860320TolC family type I secretion outer membrane protein 
 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.
 






2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.
 






3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.
 







Homology Effector list
BTH_I0068 , BCAL0343, BTH_I2693, BTH_I2697, BTH_I2698, BTH_I2705, BTH_I3225, BTH_I3226, BTH_I3226, BTH_I3225, BTH_II0310

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1BP1026B_I006975957..76397 [+], 441386860195hypothetical protein BTH_I0068
2BP1026B_I0189(hcp-1)180175..180696 [+], 522386860309type VI secretion system BCAL0343
3BP1026B_I20192253248..2256088 [-], 2841386862084Rhs element Vgr protein BTH_I2693
4BP1026B_I20252258225..2261542 [-], 3318386862090hypothetical protein BTH_I2697
5BP1026B_I20262261669..2263210 [-], 1542386862091hypothetical protein BTH_I2698
6BP1026B_I20312266194..2268992 [-], 2799386862096Rhs element Vgr protein BTH_I2705
7BP1026B_II008288329..91115 [+], 2787386863816Rhs element Vgr protein BTH_I3225
8BP1026B_II008391129..93369 [+], 2241386863817hypothetical protein BTH_I3226
9BP1026B_II12821604949..1607189 [-], 2241386864979hypothetical protein BTH_I3226
10BP1026B_II12831607203..1609989 [-], 2787386864980Rhs element Vgr protein BTH_I3225
11BP1026B_II21762701489..2702394 [+], 906386865848lectin BTH_II0310

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Proteins        Genes

Homology Immunity protein list
BTH_I0069, BTH_I2700

Immunity protein identified
#Locus tag(Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1BP1026B_I007076384..76752 [+], 369386860196lipoprotein BTH_I0069
2BP1026B_I20292264664..2264951 [-], 288386862094hypothetical protein BTH_I2700

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Proteins        Genes
N/A