SecReT6
I. Summary
SecReT6 ID693 insolico
StrainBurkholderia pseudomallei BPC006
Repliconchromosome I [Browse all T6SS(s) in this replicon]
AccessionNC_018527
Location3575917..3595902
Comment
FunctionN/A
T6SS TypeType i; subtype i4b
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
ComponentTssHTssDTssLTssITssATssBTssCTssETssF
Number111001111
ComponentTssGTssJTssKTssM
Number1111
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III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1BPC006_I37003572042..3573490 [+], 1449403520316TolC family type I secretion outer membrane protein 
2BPC006_I37013573487..3573624 [+], 138403520317hypothetical protein 
3BPC006_I37023573700..3574668 [-], 969403520318hypothetical protein 
4BPC006_I37033574680..3575645 [+], 966403520319D-alanyl-D-alanine carboxypeptidase 
5BPC006_I37043575796..3575909 [+], 114403520320hypothetical protein 
6BPC006_I37053575917..3579810 [+], 3894403520321hypothetical protein  TssM
7BPC006_I37063579807..3580796 [+], 990403520322hypothetical protein 
8BPC006_I37073580801..3581733 [+], 933403520323ompA family protein  TagL
9BPC006_I37093583143..3585812 [-], 2670403520324ClpA/B type protease  TssH
10BPC006_I37103585846..3586946 [-], 1101403520325hypothetical protein  TssG
11BPC006_I37113586910..3588748 [-], 1839403520326hypothetical protein  TssF
12BPC006_I37123588828..3589310 [-], 483403520327hypothetical protein  TssE
13BPC006_I37133589368..3589862 [-], 495403520328hypothetical protein  TssD
14BPC006_I37143589944..3591434 [-], 1491403520329hypothetical protein  TssC
15BPC006_I37153591451..3591969 [-], 519403520330hypothetical protein  TssB
16BPC006_I37163592006..3592641 [-], 636403520331hypothetical protein 
17BPC006_I37173592803..3592940 [-], 138403520332hypothetical protein 
18BPC006_I37183593051..3593665 [+], 615403520333lipoprotein  TssJ
19BPC006_I37193593774..3595120 [+], 1347403520334hypothetical protein  TssK
20BPC006_I37203595117..3595902 [+], 786403520335hypothetical protein  TssL
21BPC006_I37213596004..3596369 [+], 366403520336phage tail completion protein 
22BPC006_I37223597458..3597874 [-], 417403520337DNA methylase 
23BPC006_I37233597959..3598156 [-], 198403520338bacteriophage tail protein I 
24BPC006_I37243598363..3598662 [-], 300403520339bacteriophage baseplate assembly protein J 
25BPC006_I37253598976..3599584 [-], 609403520340ISBma1, transposase 
26BPC006_I37263599548..3600195 [-], 648403520341ISBma1, transposase 
 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.
 






2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.
 






3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.
 







Homology Effector list
BTH_I0068 , BTH_I2705, BTH_I2698, BTH_I2697, BTH_I2693, BCAL0343, BTH_I3225, BTH_II0090, BTH_I3226, BTH_I3225, BTH_II0310

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1BPC006_I007775552..76520 [+], 969403516745hypothetical protein BTH_I0068
2BPC006_I16501586894..1589701 [+], 2808403518304Rhs element Vgr protein BTH_I2705
3BPC006_I16541592179..1594227 [+], 2049403518308hypothetical protein BTH_I2698
4BPC006_I16561594336..1597671 [+], 3336403518310Rhs element Vgr protein BTH_I2697
5BPC006_I16601599807..1602647 [+], 2841403518314Rhs element Vgr protein BTH_I2693
6BPC006_I37133589368..3589862 [-], 495403520328hypothetical protein BCAL0343
7BPC006_II010288359..91139 [+], 2781403521396Rhs element Vgr protein BTH_I3225
8BPC006_II010391153..93393 [+], 2241403521397Type V secretory pathway, adhesin AidA BTH_II0090
9BPC006_II16121635452..1637692 [-], 2241403522893hypothetical protein BTH_I3226
10BPC006_II16131637706..1640492 [-], 2787403522894Rhs element Vgr protein BTH_I3225
11BPC006_II27232746518..2747423 [+], 906403524001hypothetical protein BTH_II0310

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Proteins        Genes

Homology Immunity protein list
BTH_I0069, BTH_I2700

Immunity protein identified
#Locus tag(Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1BPC006_I007876507..76875 [+], 369403516746lipoprotein BTH_I0069
2BPC006_I16521590723..1591232 [+], 510403518306hypothetical protein BTH_I2700

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Proteins        Genes
N/A