SecReT6
I. Summary
SecReT6 ID697 insolico
StrainBurkholderia pseudomallei BPC006
Repliconchromosome II [Browse all T6SS(s) in this replicon]
AccessionNC_018529
Location2047220..2071131
Comment
FunctionN/A
T6SS TypeType i; subtype i1
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
ComponentTssHTssDTssLTssITssATssBTssCTssETssF
Number111101111
ComponentTssGTssJTssKTssM
Number1111
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III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1BPC006_II20052044382..2045119 [-], 738403523285DNA-binding response regulator  VirG
2BPC006_II20062045116..2046960 [-], 1845403523286sensor histidine kinase  VirA
3BPC006_II20072047091..2047201 [-], 111403523287hypothetical protein 
4BPC006_II20082047220..2047714 [+], 495403523288hypothetical protein  TssB
5BPC006_II20092047738..2049237 [+], 1500403523289hypothetical protein  TssC
6BPC006_II20102049457..2049966 [+], 510403523290hcp protein  TssD
7BPC006_II20112049959..2050420 [+], 462403523291hypothetical protein  TssE
8BPC006_II20122050457..2052199 [+], 1743403523292hypothetical protein  TssF
9BPC006_II20132052163..2053209 [+], 1047403523293hypothetical protein  TssG
10BPC006_II20142053196..2056252 [+], 3057403523294ATP-dependent Clp protease, ATP-binding subunit ClpB  TssH
11BPC006_II20152056279..2059302 [+], 3024403523295Rhs element Vgr protein  TssI
12BPC006_II20162059328..2061961 [+], 2634403523296pentapeptide repeat-containing protein 
13BPC006_II20172061979..2063043 [+], 1065403523297pentapeptide repeat-containing protein 
14BPC006_II20182063022..2063795 [+], 774403523298hypothetical protein 
15BPC006_II20192063824..2064216 [+], 393403523299hypothetical protein 
16BPC006_II20202064226..2065023 [+], 798403523300hypothetical protein  TssJ
17BPC006_II20212065020..2066453 [+], 1434403523301hypothetical protein  TssK
18BPC006_II20222066450..2067115 [+], 666403523302hypothetical protein  TssL
19BPC006_II20232067112..2071131 [+], 4020403523303hypothetical protein  TssM
20BPC006_II20242071264..2071356 [-], 93403523304hypothetical protein 
21BPC006_II20252071316..2071516 [-], 201403523305hypothetical protein 
22BPC006_II20262071537..2071719 [-], 183403523306hypothetical protein 
23BPC006_II20272071997..2072191 [-], 195403523307hypothetical protein 
24BPC006_II20282072265..2073119 [+], 855403523308hypothetical protein  BMAA0729 (e)
25BPC006_II20292073079..2073336 [-], 258403523309hypothetical protein 
26BPC006_II20302073337..2073447 [-], 111403523310hypothetical protein 
27BPC006_II20312073484..2073591 [-], 108403523311hypothetical protein 
28BPC006_II20322073792..2073914 [+], 123403523312hypothetical protein 
29BPC006_II20332074203..2074340 [-], 138403523313hypothetical protein 
30BPC006_II20342074363..2074650 [+], 288403523314ChnZ 
 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.
 






2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.
 






3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.
 







Homology Effector list
BMAA0742 , BMAA0737, BMAA0729

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1BPC006_II20102049457..2049966 [+], 510403523290hcp protein BMAA0742
2BPC006_II20152056279..2059302 [+], 3024403523295Rhs element Vgr protein BMAA0737
3BPC006_II20282072265..2073119 [+], 855403523308hypothetical protein BMAA0729

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Proteins        Genes
N/A
N/A