I. Summary
SecReT6 ID699 insolico
StrainEscherichia coli O104:H4 str. 2009EL-2050
Repliconchromosome [Browse all T6SS(s) in this replicon]
T6SS TypeType i; subtype i4b
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
Click the above image to have a larger view
III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1O3M_04285877943..878155 [+], 213410480990hemolysin expression-modulating protein 
2O3M_04290878772..879341 [+], 570410480991hypothetical protein 
3O3M_04295879509..879892 [+], 384410480992hypothetical protein 
4O3M_04300879882..880301 [+], 420410480993hypothetical protein 
5O3M_04305880307..880489 [+], 183410480994hypothetical protein 
6O3M_04310880610..881233 [+], 624410480995hypothetical protein 
7O3M_04315881329..881562 [+], 234410480996hypothetical protein 
8O3M_04320881615..881806 [-], 192410480997hypothetical protein 
9O3M_04325882313..882810 [+], 498410480998hypothetical protein  TssB
10O3M_04330882832..884193 [+], 1362410480999hypothetical protein  TssC
11O3M_04335884295..885539 [+], 1245410481000hypothetical protein 
12O3M_04340885856..887520 [+], 1665410481001UvrD/REP helicase 
13O3M_04345887582..887890 [+], 309410481002hypothetical protein 
14O3M_04350887945..888172 [+], 228410481003transcriptional regulator IbrB 
15O3M_04355888251..888520 [+], 270410481004transcriptional regulator 
16O3M_04360888541..889185 [+], 645410481005hypothetical protein 
17O3M_04365889251..889574 [+], 324410481006hypothetical protein 
18O3M_04370889628..890023 [-], 396410481007hypothetical protein 
19O3M_04380890394..890780 [+], 387410481008hypothetical protein 
20O3M_04400892301..892777 [+], 477410481009hypothetical protein  TssB
21O3M_04405892780..894258 [+], 1479410481010hypothetical protein  TssC
22O3M_04410894268..894774 [+], 507410481011hypothetical protein  AaiC (e)
23O3M_04415894784..895206 [+], 423410481012hypothetical protein  TssE
24O3M_04420895242..895538 [-], 297410481013hypothetical protein 
25O3M_04425895670..897001 [+], 1332410481014hypothetical protein  TssF
26O3M_04430896992..897924 [+], 933410481015hypothetical protein  TssG
27O3M_04435897937..899919 [+], 1983410481016hypothetical protein  TssI
28O3M_04440899930..900397 [+], 468410481017hypothetical protein 
29O3M_04445900401..900706 [+], 306410481018hypothetical protein  PAAR
30O3M_04450900710..901786 [+], 1077410481019hypothetical protein  TssA
31O3M_04455901794..902345 [+], 552410481020hypothetical protein  TssJ
32O3M_04460902364..903776 [+], 1413410481021hypothetical protein  TssK
33O3M_04465903804..904118 [+], 315410481022hypothetical protein 
34O3M_04470904115..904705 [+], 591410481023hypothetical protein  TssL
35O3M_04475904702..908115 [+], 3414410481024hypothetical protein  TssM
36O3M_04480908119..910668 [+], 2550410481025hypothetical protein  TssH
37O3M_04490911705..912076 [+], 372410481026transposase 
38O3M_04495913834..914400 [+], 567410481027hypothetical protein 
39O3M_04500914545..914778 [-], 234410481028hypothetical protein 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

Download FASTA format files
Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Homology Effector list

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1O3M_04410894268..894774 [+], 507410481011hypothetical protein EC042_4564

Download FASTA format files
Proteins        Genes