SecReT6
I. Summary
SecReT6 ID700 insolico
StrainEscherichia coli O104:H4 str. 2009EL-2050
Repliconchromosome [Browse all T6SS(s) in this replicon]
AccessionNC_018650
Location4146167..4187697
Comment
FunctionN/A
T6SS TypeType i; subtype i1
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
ComponentTssHTssDTssLTssITssATssBTssCTssETssF
Number121111211
ComponentTssGTssJTssKTssM
Number1111
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III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1O3M_20185 (prfH)4142596..4143210 [-], 615410484114peptide chain release factor-like protein 
2O3M_201904143207..4144346 [-], 1140410484115hypothetical protein 
3O3M_201954144592..4145044 [-], 453410484116acyltransferase 
4O3M_202004145041..4146096 [-], 1056410484117DNA polymerase IV 
5O3M_202054146167..4146952 [-], 786410484118hypothetical protein  TagL
6O3M_202104146897..4148636 [+], 1740410484119flagellar system protein 
7O3M_202154148741..4149019 [+], 279410484120hypothetical protein 
8O3M_202204149012..4149368 [+], 357410484121HicB protein 
9O3M_202254149425..4150174 [-], 750410484122hydrolase 
10O3M_202304150384..4150644 [+], 261410484123DNA-damage-inducible protein J 
11O3M_202354150647..4150925 [+], 279410484124toxin of the YafQ-DinJ toxin-antitoxin system 
12O3M_202404151081..4151821 [+], 741410484125hypothetical protein 
13O3M_202454151792..4152559 [-], 768410484126amidotransferase 
14O3M_20250 (gmhA)4152765..4153343 [-], 579410484127phosphoheptose isomerase 
15O3M_20255 (fadE)4153583..4156027 [+], 2445410484128acyl-CoA dehydrogenase 
16O3M_202604156070..4156543 [-], 474410484129C-lysozyme inhibitor 
17O3M_202654156697..4157467 [+], 771410484130C-N hydrolase family amidase 
18O3M_202704157509..4158570 [-], 1062410484131transposase 
19O3M_202854160055..4160537 [-], 483410484132hypothetical protein 
20O3M_202904160521..4161711 [-], 1191410484133Rhs Core protein 
21O3M_202954161680..4164184 [-], 2505410484134Rhs core protein  PAAR
22O3M_203004164260..4166401 [-], 2142410484135hypothetical protein  TssI
23O3M_203054166611..4167129 [-], 519410484136hypothetical protein  TssD
24O3M_203104167256..4167399 [-], 144410484137hypothetical protein 
25O3M_203154167826..4168326 [+], 501410484138hypothetical protein  TssB
26O3M_203204168361..4168585 [+], 225410484139hypothetical protein  TssC
27O3M_203254168636..4170111 [+], 1476410484140hypothetical protein  TssC
28O3M_203304170118..4170531 [+], 414410484141hypothetical protein  TssE
29O3M_203354170535..4172385 [+], 1851410484142type VI secretion system protein ImpG  TssF
30O3M_203404172349..4173431 [+], 1083410484143hypothetical protein  TssG
31O3M_203454173456..4174736 [+], 1281410484144type VI secretion system protein ImpI  Fha
32O3M_203504174733..4175257 [+], 525410484145lipoprotein  TssJ
33O3M_203554175260..4176591 [+], 1332410484146hypothetical protein  TssK
34O3M_203604176596..4177357 [+], 762410484147membrane protein Aec26  TssL
35O3M_203654177366..4180125 [+], 2760410484148ATP-dependent Clp proteinase ATP-binding subunit  TssH
36O3M_203704180122..4180865 [+], 744410484149hypothetical protein 
37O3M_203754180870..4182285 [+], 1416410484150hypothetical protein 
38O3M_203804182304..4185828 [+], 3525410484151IcmF-like protein  TssM
39O3M_203854185839..4187191 [+], 1353410484152hypothetical protein  TssA
40O3M_203904187215..4187697 [+], 483410484153hypothetical protein  TssD
41O3M_203954187741..4188655 [+], 915410484154hypothetical protein 
42O3M_204004188665..4189144 [+], 480410484155hypothetical protein 
43O3M_204054189281..4190066 [-], 786410484156aminopeptidase 
44O3M_204104190602..4191333 [-], 732410484157DNA polymerase III subunit epsilon 
45O3M_20415 (rnhA)4191398..4191865 [+], 468410484158ribonuclease H 
46O3M_204204191862..4192584 [-], 723410484159S-adenosyl-L-methionine-dependent methyltransferase 
 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.
 






2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.
 






3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.
 







Homology Effector list
ABG57132

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1O3M_203054166611..4167129 [-], 519410484136hypothetical protein ABG57132

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Proteins        Genes
N/A
N/A