SecReT6
I. Summary
SecReT6 ID702 insolico
StrainEscherichia coli O104:H4 str. 2011C-3493
Repliconchromosome [Browse all T6SS(s) in this replicon]
AccessionNC_018658
Location4168458..4209988
Comment
FunctionN/A
T6SS TypeType i; subtype i1
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
ComponentTssHTssDTssLTssITssATssBTssCTssETssF
Number121121211
ComponentTssGTssJTssKTssM
Number1111
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III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1O3K_20285 (prfH)4164887..4165501 [-], 615407483574peptide chain release factor-like protein 
2O3K_202904165498..4166637 [-], 1140407483575hypothetical protein 
3O3K_202954166883..4167335 [-], 453407483576putative acyltransferase 
4O3K_203004167332..4168387 [-], 1056407483577DNA polymerase IV 
5O3K_203054168458..4169243 [-], 786407483578hypothetical protein  TagL
6O3K_203104169188..4170927 [+], 1740407483579flagellar system protein 
7O3K_203154171032..4171310 [+], 279407483580hypothetical protein 
8O3K_203204171303..4171659 [+], 357407483581putative HicB 
9O3K_203254171716..4172465 [-], 750407483582hydrolase 
10O3K_203304172675..4172935 [+], 261407483583DNA-damage-inducible protein J 
11O3K_203354172938..4173216 [+], 279407483584toxin of the YafQ-DinJ toxin-antitoxin system 
12O3K_203404173372..4174112 [+], 741407483585hypothetical protein 
13O3K_203454174083..4174850 [-], 768407483586putative amidotransfease 
14O3K_20350 (gmhA)4175056..4175634 [-], 579407483587phosphoheptose isomerase 
15O3K_20355 (fadE)4175874..4178318 [+], 2445407483588acyl-CoA dehydrogenase 
16O3K_203604178361..4178834 [-], 474407483589C-lysozyme inhibitor 
17O3K_203654178988..4179758 [+], 771407483590C-N hydrolase family amidase 
18O3K_203704179800..4180843 [-], 1044407483591transposase 
19O3K_203854182346..4182828 [-], 483407483592hypothetical protein 
20O3K_203904182812..4184002 [-], 1191407483593putative Rhs Core protein 
21O3K_203954183971..4186475 [-], 2505407483594Rhs core protein  PAAR
22O3K_204004186551..4188692 [-], 2142407483595hypothetical protein  TssI
23O3K_204054188902..4189420 [-], 519407483596hypothetical protein  TssD
24O3K_204104189547..4189690 [-], 144407483597hypothetical protein 
25O3K_204154190117..4190617 [+], 501407483598hypothetical protein  TssB
26O3K_204204190652..4190876 [+], 225407483599hypothetical protein  TssC
27O3K_204254190927..4192402 [+], 1476407483600hypothetical protein  TssC
28O3K_204304192409..4192822 [+], 414407483601hypothetical protein  TssE
29O3K_204354192826..4194676 [+], 1851407483602type VI secretion system protein ImpG  TssF
30O3K_204404194640..4195722 [+], 1083407483603hypothetical protein  TssG
31O3K_204454195747..4197027 [+], 1281407483604type VI secretion system protein ImpI  Fha
32O3K_204504197024..4197548 [+], 525407483605lipoprotein  TssJ
33O3K_204554197551..4198882 [+], 1332407483606hypothetical protein  TssK
34O3K_204604198887..4199648 [+], 762407483607putative membrane protein Aec26  TssL
35O3K_204654199657..4202416 [+], 2760407483608ATP-dependent Clp proteinase ATP-binding subunit  TssH
36O3K_204704202413..4203156 [+], 744407483609hypothetical protein 
37O3K_204754203161..4204576 [+], 1416407483610hypothetical protein  TssA
38O3K_204804204595..4208119 [+], 3525407483611IcmF-like protein  TssM
39O3K_204854208130..4209482 [+], 1353407483612hypothetical protein  TssA
40O3K_204904209506..4209988 [+], 483407483613hypothetical protein  TssD
41O3K_204954210032..4210946 [+], 915407483614hypothetical protein 
42O3K_205004210956..4211435 [+], 480407483615hypothetical protein 
43O3K_205054211572..4212357 [-], 786407483616aminopeptidase 
44O3K_205104212893..4213624 [-], 732407483617DNA polymerase III subunit epsilon 
45O3K_20515 (rnhA)4213689..4214156 [+], 468407483618ribonuclease H 
46O3K_205204214153..4214875 [-], 723407483619S-adenosyl-L-methionine-dependent methyltransferase 
 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.
 






2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.
 






3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.
 







Homology Effector list
ABG57132

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1O3K_204054188902..4189420 [-], 519407483596hypothetical protein ABG57132

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Proteins        Genes
N/A
N/A