SecReT6
I. Summary
SecReT6 ID704 insolico
StrainEscherichia coli O104:H4 str. 2009EL-2071
Repliconchromosome [Browse all T6SS(s) in this replicon]
AccessionNC_018661
Location4205139..4246669
Comment
FunctionN/A
T6SS TypeType i; subtype i1
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
ComponentTssHTssDTssLTssITssATssBTssCTssETssF
Number121121211
ComponentTssGTssJTssKTssM
Number1111
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III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1O3O_05095 (prfH)4201568..4202182 [-], 615407467709peptide chain release factor-like protein 
2O3O_050904202179..4203318 [-], 1140407467708hypothetical protein 
3O3O_050854203564..4204016 [-], 453407467707acyltransferase 
4O3O_050804204013..4205068 [-], 1056407467706DNA polymerase IV 
5O3O_050754205139..4205924 [-], 786407467705hypothetical protein  TagL
6O3O_050704205869..4207608 [+], 1740407467704flagellar system protein 
7O3O_050654207713..4207991 [+], 279407467703hypothetical protein 
8O3O_050604207984..4208340 [+], 357407467702HicB 
9O3O_050554208397..4209146 [-], 750407467701hydrolase 
10O3O_050504209356..4209616 [+], 261407467700DNA-damage-inducible protein J 
11O3O_050454209619..4209897 [+], 279407467699toxin of the YafQ-DinJ toxin-antitoxin system 
12O3O_050404210053..4210793 [+], 741407467698hypothetical protein 
13O3O_050354210764..4211531 [-], 768407467697amidotransfease 
14O3O_05030 (gmhA)4211737..4212315 [-], 579407467696phosphoheptose isomerase 
15O3O_05025 (fadE)4212555..4214999 [+], 2445407467695acyl-CoA dehydrogenase 
16O3O_050204215042..4215515 [-], 474407467694C-lysozyme inhibitor 
17O3O_050154215669..4216439 [+], 771407467693C-N hydrolase family amidase 
18O3O_050104216481..4217524 [-], 1044407467692transposase 
19O3O_049954219027..4219509 [-], 483407467691hypothetical protein 
20O3O_049904219493..4220683 [-], 1191407467690Rhs Core protein 
21O3O_049854220652..4223156 [-], 2505407467689Rhs core protein  PAAR
22O3O_049804223232..4225373 [-], 2142407467688hypothetical protein  TssI
23O3O_049754225583..4226101 [-], 519407467687hypothetical protein  TssD
24O3O_049704226228..4226371 [-], 144407467686hypothetical protein 
25O3O_049654226798..4227298 [+], 501407467685hypothetical protein  TssB
26O3O_049604227333..4227557 [+], 225407467684hypothetical protein  TssC
27O3O_049554227608..4229083 [+], 1476407467683hypothetical protein  TssC
28O3O_049504229090..4229503 [+], 414407467682hypothetical protein  TssE
29O3O_049454229507..4231357 [+], 1851407467681type VI secretion system protein ImpG  TssF
30O3O_049404231321..4232403 [+], 1083407467680hypothetical protein  TssG
31O3O_049354232428..4233708 [+], 1281407467679type VI secretion system protein ImpI  Fha
32O3O_049304233705..4234229 [+], 525407467678lipoprotein  TssJ
33O3O_049254234232..4235563 [+], 1332407467677hypothetical protein  TssK
34O3O_049204235568..4236329 [+], 762407467676membrane protein Aec26  TssL
35O3O_049154236338..4239097 [+], 2760407467675ATP-dependent Clp proteinase ATP-binding subunit  TssH
36O3O_049104239094..4239837 [+], 744407467674hypothetical protein 
37O3O_049054239842..4241257 [+], 1416407467673hypothetical protein  TssA
38O3O_049004241276..4244800 [+], 3525407467672IcmF-like protein  TssM
39O3O_048954244811..4246163 [+], 1353407467671hypothetical protein  TssA
40O3O_048904246187..4246669 [+], 483407467670hypothetical protein  TssD
41O3O_048854246713..4247627 [+], 915407467669hypothetical protein 
42O3O_048804247637..4248116 [+], 480407467668hypothetical protein 
43O3O_048754248253..4249038 [-], 786407467667aminopeptidase 
44O3O_048704249574..4250305 [-], 732407467666DNA polymerase III subunit epsilon 
45O3O_04865 (rnhA)4250370..4250837 [+], 468407467665ribonuclease H 
46O3O_048604250834..4251556 [-], 723407467664S-adenosyl-L-methionine-dependent methyltransferase 
 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.
 






2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.
 






3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.
 







Homology Effector list
ABG57132

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1O3O_049754225583..4226101 [-], 519407467687hypothetical protein ABG57132

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Proteins        Genes
N/A
N/A