SecReT6
I. Summary
SecReT6 ID723 insolico
StrainSerratia marcescens FGI94
Repliconchromosome [Browse all T6SS(s) in this replicon]
AccessionNC_020064
Location1749566..1796753
Comment
FunctionN/A
T6SS TypeType i; subtype i2
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
ComponentTssHTssDTssLTssITssATssBTssCTssETssF
Number111121111
ComponentTssGTssJTssKTssM
Number1111
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III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1D781_16541745311..1745478 [+], 168440230345ribosome modulation factor 
2D781_16551745871..1746359 [+], 489440230346hypothetical protein 
3D781_16561746452..1746970 [-], 519440230347beta-hydroxyacyl-(acyl carrier protein) dehydratase FabA 
4D781_16571747039..1748808 [-], 1770440230348putative ATP-dependent protease 
5D781_16581748996..1749454 [+], 459440230349hypothetical protein 
6D781_16591749566..1750633 [-], 1068440230350outer membrane protein/peptidoglycan-associated (lipo)protein  TagL
7D781_16601750995..1751507 [-], 513440230351SOS-response cell division inhibitor, blocks FtsZ ring formation 
8D781_16611751738..1752343 [+], 606440230352regulator of competence-specific genes 
9D781_16621752388..1754523 [-], 2136440230353putative membrane protein, TIGR01666 
10D781_16631754550..1755002 [-], 453440230354hypothetical protein 
11D781_16641755162..1757216 [+], 2055440230355DNA/RNA helicase, superfamily I 
12D781_16651757252..1757710 [-], 459440230356methylglyoxal synthase 
13D781_16661757839..1758393 [-], 555440230357hypothetical protein 
14D781_16671758446..1758538 [+], 93440230358hypothetical protein 
15D781_16681758686..1759099 [+], 414440230359putative CoA-binding protein 
16D781_16691759154..1759471 [-], 318440230360hemimethylated DNA binding domain protein 
17D781_16701759549..1760733 [-], 1185440230361putative SAM-dependent methyltransferase 
18D781_16711760978..1761256 [+], 279440230362acylphosphatase 
19D781_16721761268..1761597 [-], 330440230363sulfur relay protein, TusE/DsrC/DsvC family 
20D781_16731761773..1762858 [+], 1086440230364theronine dehydrogenase-like Zn-dependent dehydrogenase 
21D781_16741762929..1763585 [-], 657440230365FtsH-interacting integral membrane protein 
22D781_16761764726..1765223 [+], 498440230366type VI secretion protein, VC_A0107 family  TssB
23D781_16771765257..1766804 [+], 1548440230367type VI secretion protein, EvpB/VC_A0108 family  TssC
24D781_16781766817..1768157 [+], 1341440230368type VI secretion protein, VC_A0114 family  TssK
25D781_16791768154..1768828 [+], 675440230369type IV / VI secretion system protein, DotU family  TssL
26D781_16801768825..1770537 [+], 1713440230370outer membrane protein/peptidoglycan-associated (lipo)protein  TagL
27D781_16811770539..1771030 [+], 492440230371type VI secretion system effector, Hcp1 family  TssD
28D781_16821771304..1773943 [+], 2640440230372type VI secretion ATPase, ClpV1 family  TssH
29D781_16831773946..1776324 [+], 2379440230373Rhs element Vgr protein  TssI
30D781_16841776325..1777089 [+], 765440230374hypothetical protein 
31D781_16851777168..1777695 [+], 528440230375Protein of unknown function (DUF3304) 
32D781_16861777767..1778294 [+], 528440230376Protein of unknown function (DUF3304) 
33D781_16871778366..1778893 [+], 528440230377Protein of unknown function (DUF3304) 
34D781_16881778881..1781322 [+], 2442440230378hypothetical protein 
35D781_16891781336..1781593 [+], 258440230379hypothetical protein  PAAR
36D781_16901781623..1782729 [+], 1107440230380hypothetical protein 
37D781_16911782713..1786132 [+], 3420440230381hypothetical protein  TssM
38D781_16921787072..1788676 [+], 1605440230382type VI secretion-associated protein, VC_A0119 family  TssA
39D781_16931788720..1790474 [+], 1755440230383type VI secretion protein, VC_A0110 family  TssF
40D781_16941790438..1791523 [+], 1086440230384type VI secretion protein, VC_A0111 family  TssG
41D781_16951791501..1792043 [+], 543440230385type VI secretion lipoprotein, VC_A0113 family  TssJ
42D781_16961792113..1792799 [+], 687440230386phosphatidylglycerophosphate synthase 
43D781_16971792789..1793439 [+], 6514402303871-acyl-sn-glycerol-3-phosphate acyltransferase 
44D781_16981793436..1794371 [+], 936440230388putative CDP-diglyceride synthetase/phosphatidate cytidylyltransferase 
45D781_16991794395..1794841 [+], 447440230389type VI secretion system lysozyme-related protein  TssE
46D781_17011795383..1796753 [+], 1371440230390hypothetical protein  TssA
47D781_17021796732..1797886 [-], 11554402303912-polyprenyl-6-methoxyphenol hydroxylase-like oxidoreductase 
48D781_17031798234..1799616 [+], 1383440230392xanthine permease 
49D781_17041799594..1800094 [+], 501440230393OHCU decarboxylase 
50D781_17051800091..1800423 [+], 333440230394hydroxyisourate hydrolase 
 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.
 






2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.
 






3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.
 







Homology Effector list
EC042_4529

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1D781_16811770539..1771030 [+], 492440230371type VI secretion system effector, Hcp1 family EC042_4529

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Proteins        Genes
N/A
N/A