I. Summary
SecReT6 ID822 insolico
StrainSalmonella enterica subsp. enterica serovar Typhimurium var. 5- str. CFSAN001921
Repliconchromosome [Browse all T6SS(s) in this replicon]
T6SS TypeType i; subtype i3
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
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III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1CFSAN001921_159453229964..3230227 [-], 264525841087hypothetical protein 
2CFSAN001921_159503230221..3234315 [-], 4095525841088type IV secretion protein Rhs  PAAR
3CFSAN001921_159553234334..3234780 [-], 447525839266hypothetical protein 
4CFSAN001921_159603234804..3236993 [-], 2190525839267type VI secretion protein Vgr  TssI
5CFSAN001921_159653237390..3237908 [-], 519525841089SPI-6 associated protein 
6CFSAN001921_159703237935..3238321 [-], 387525841090hypothetical protein 
7CFSAN001921_159753238348..3239136 [-], 789525839268hypothetical protein 
8CFSAN001921_159803239136..3243005 [-], 3870525839269membrane protein  TssM
9CFSAN001921_159853243039..3243482 [-], 444525839270Shiga toxin A subunit 
10CFSAN001921_159903243673..3244446 [-], 774525841091membrane protein 
11CFSAN001921_159953244451..3245755 [-], 1305525839271membrane protein  TssL
12CFSAN001921_160003245752..3247095 [-], 1344525839272type VI secretion protein  TssK
13CFSAN001921_160053247099..3247635 [-], 537525839273outer membrane lipoprotein  TssJ
14CFSAN001921_160103247702..3248187 [-], 486525839274Hcp1 family type VI secretion system effector  TssD
15CFSAN001921_160153248330..3248713 [-], 384525839275hypothetical protein  STM0278 (i)
16CFSAN001921_160203248698..3249183 [-], 486525839276hypothetical protein  STM0277 (e)
17CFSAN001921_160253249488..3249973 [-], 486525839277Hcp1 family type VI secretion system effector  TssD
18CFSAN001921_160303250859..3252367 [-], 1509525839278EvpB family type VI secretion protein  TssC
19CFSAN001921_160353252391..3252933 [-], 543525839279type VI secretion protein  TssB
20CFSAN001921_160403253033..3255672 [-], 2640525839280protein disaggregation chaperone  TssH
21CFSAN001921_160453256040..3256942 [+], 903525839281hypothetical protein 
22CFSAN001921_160503256929..3257753 [+], 825525839282hypothetical protein  TagJ
23CFSAN001921_160553257750..3258244 [+], 495525839283cytoplasmic protein  TssE
24CFSAN001921_160603258260..3260143 [+], 1884525841092type VI secretion protein  TssF
25CFSAN001921_160653260140..3261135 [+], 996525839284SPI-6 associated protein  TssG
26CFSAN001921_160703261146..3262201 [+], 1056525839285hypothetical protein  TssA
27CFSAN001921_160803262733..3263473 [-], 741525839286DNA polymerase III subunit epsilon 
28CFSAN001921_160853263528..3263995 [+], 468525839287ribonuclease H 
29CFSAN001921_160903263992..3264714 [-], 723525839288hypothetical protein 
30CFSAN001921_160953264749..3265504 [+], 756525839289hydroxyacylglutathione hydrolase 
31CFSAN001921_16100 (mltD)3265576..3266943 [+], 1368525839290membrane protein 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Homology Effector list
ROD_34191 , EvpC, STM0277, EvpC, STY2606

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1CFSAN001921_01365275988..276473 [+], 486525837011hypothetical protein ROD_34191
2CFSAN001921_160103247702..3248187 [-], 486525839274Hcp1 family type VI secretion system effector EvpC
3CFSAN001921_160203248698..3249183 [-], 486525839276hypothetical protein STM0277
4CFSAN001921_160253249488..3249973 [-], 486525839277Hcp1 family type VI secretion system effector EvpC
5CFSAN001921_049101028787..1029155 [-], 369525840654hypothetical protein STY2606

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Proteins        Genes

Homology Immunity protein list
STY2607, STM0278

Immunity protein identified
#Locus tag(Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1CFSAN001921_049051028269..1028787 [-], 519525837536hypothetical protein STY2607
2CFSAN001921_160153248330..3248713 [-], 384525839275hypothetical protein STM0278

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Proteins        Genes