SecReT6
I. Summary
SecReT6 ID838 experimental
StrainProteus mirabilis BB2000
Repliconchromosome [Browse all T6SS(s) in this replicon]
AccessionNC_022000
Location916585..943300
CommentSelf-recognition and territoriality
Functionanti-bacterial; effector translocation
T6SS TypeType i; subtype i1
experimental Experimental investigation has been performed on this T6SS.

II. T6SS components
ComponentTssHTssDTssLTssITssATssBTssCTssETssF
Number121121112
ComponentTssGTssJTssKTssM
Number1111
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III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1BB2000_0801 (aphA)912111..912854 [+], 744529236499acid phosphatase/phosphotransferase 
2BB2000_0802913197..914912 [+], 1716529236500hypothetical protein 
3BB2000_0803915244..915792 [+], 549529236501hypothetical protein 
4BB2000_0804915842..916492 [+], 651529236502metallo-beta-lactamase superfamily protein 
5BB2000_0805 (tssQ)916585..917058 [-], 474529236503TssQ  TssD
6BB2000_0806 (tssP)917149..918885 [-], 1737529236504TssP  TssF
7BB2000_0807 (tssO)918878..920233 [-], 1356529236505TssO  TssA
8BB2000_0808 (tssN)920271..923819 [-], 3549529236506TssN  TssM
9BB2000_0809 (tssM)923822..925285 [-], 1464529236507TssM  TssA
10BB2000_0810 (tssL)925291..925941 [-], 651529236508TssL 
11BB2000_0811 (tssK)925943..926731 [-], 789529236509TssK 
12BB2000_0812 (tssJ)926735..929446 [-], 2712529236510TssJ  TssH
13BB2000_0813 (tssI)929455..930210 [-], 756529236511TssI  TssL
14BB2000_0814 (tssH)930203..931561 [-], 1359529236512TssH  TssK
15BB2000_0815 (tssG)931563..932114 [-], 552529236513TssG  TssJ
16BB2000_0816 (tssF)932116..933384 [-], 1269529236514TssF  Fha
17BB2000_0817 (tssE)933389..934426 [-], 1038529236515TssE  TssG
18BB2000_0818 (tssD)934390..936165 [-], 1776529236516TssD  TssF
19BB2000_0819 (tssC)936173..936604 [-], 432529236517TssC  TssE
20BB2000_0820 (tssB)936610..938088 [-], 1479529236518TssB  TssC
21BB2000_0821 (tssA)938109..938609 [-], 501529236519TssA  TssB
22BB2000_0822 (idrA)940506..941024 [+], 519529236520IdrA  TssD
23BB2000_0823 (idrB)941108..943300 [+], 2193529236521IdrB  TssI
24BB2000_0824 (idrC)943326..943745 [+], 420529236522IdrC 
 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

Download FASTA format files
Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.
 






2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.
 






3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.
 







Homology Effector list
idrA , idrB, idsA, idsB, idsD

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1BB2000_0822(idrA)940506..941024 [+], 519529236520IdrA idrA
2BB2000_0823(idrB)941108..943300 [+], 2193529236521IdrB idrB
3BB2000_3002(idsA)3275686..3276204 [+], 519529238652IdsA idsA
4BB2000_3003(idsB)3276277..3278448 [+], 2172529238653IdsB idsB
5BB2000_3005(idsD)3279668..3282772 [+], 3105529238655IdsD idsD
Data from experimental literature

Download FASTA format files
Proteins        Genes
N/A
(1) Alteri CJ et al. (2013). Multicellular Bacteria Deploy the Type VI Secretion System to Preemptively Strike Neighboring Cells. PLoS Pathog. 9(9):e1003608. [PudMed:24039579] experimental in_silico
(2) Wenren LM et al. (2013). Two Independent Pathways for Self-Recognition in Proteus mirabilis Are Linked by Type VI-Dependent Export. MBio. 4(4). [PudMed:23882014] experimental
(3) Gibbs KA et al. (2008). Genetic determinants of self identity and social recognition in bacteria. Science. 321(5886):256-9. [PudMed:18621670] experimental
 
experimental This literature contains experimental investigation
in_silico This literature contains bioinformatics investigation