SecReT6
I. Summary
SecReT6 ID853 insolico
StrainEscherichia coli PMV-1
Repliconchromosome [Browse all T6SS(s) in this replicon]
AccessionNC_022370
Location3144886..3174640
Comment
FunctionN/A
T6SS TypeType i; subtype i2
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
ComponentTssHTssDTssLTssITssATssBTssCTssETssF
Number111121111
ComponentTssGTssJTssKTssM
Number1111
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III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1ECOPMV1_03068 (csdA)3140066..3141271 [+], 1206544577328Cysteine sulfinate desulfinase 
2ECOPMV1_03069 (ygdK)3141271..3141714 [+], 444544577329putative sufE-like protein ygdK 
3ECOPMV1_03070 (moeB_2)3141765..3142571 [-], 807544577330Molybdopterin-synthase adenylyltransferase 
4ECOPMV1_03071 (mltA)3142648..3143745 [-], 1098544577331Membrane-bound lytic murein transglycosylase A precursor 
5ECOPMV1_030753144886..3145386 [+], 501544577332hypothetical protein  TssB
6ECOPMV1_030763145445..3146983 [+], 1539544577333hypothetical protein  TssC
7ECOPMV1_030773147001..3148338 [+], 1338544577334hypothetical protein  TssK
8ECOPMV1_030783148335..3149000 [+], 666544577335hypothetical protein  TssL
9ECOPMV1_03079 (yiaD_1)3149013..3150665 [+], 1653544577336Inner membrane lipoprotein YiaD precursor  TagL
10ECOPMV1_03080 (hcpA_3)3150723..3151214 [+], 492544577337Secreted protein hcp  TssD
11ECOPMV1_03081 (clpV1_2)3151406..3154051 [+], 2646544577338hypothetical protein  TssH
12ECOPMV1_030823154063..3156543 [+], 2481544577339hypothetical protein  TssI
13ECOPMV1_030833156563..3158332 [+], 1770544577340PGAP1-like protein  Tle4 (e)
14ECOPMV1_030843158307..3159140 [+], 834544577341hypothetical protein  Tli4 (i)
15ECOPMV1_030853159109..3159402 [+], 294544577342hypothetical protein 
16ECOPMV1_030863159866..3160126 [+], 261544577343hypothetical protein  PAAR
17ECOPMV1_030873160128..3161264 [+], 1137544577344hypothetical protein 
18ECOPMV1_030883161274..3164627 [+], 3354544577345hypothetical protein  TssM
19ECOPMV1_030893164593..3166230 [+], 1638544577346hypothetical protein  TssA
20ECOPMV1_030903166236..3167813 [+], 1578544577347Pyocin large subunit  PAAR
21ECOPMV1_030913167888..3168442 [+], 555544577348hypothetical protein 
22ECOPMV1_030923168699..3169142 [+], 444544577349hypothetical protein 
23ECOPMV1_030933169512..3171272 [+], 1761544577350hypothetical protein  TssF
24ECOPMV1_030943171236..3172315 [+], 1080544577351hypothetical protein  TssG
25ECOPMV1_030953172296..3172832 [+], 537544577352hypothetical protein  TssJ
26ECOPMV1_030963172836..3173264 [+], 429544577353type VI secretion system lysozyme-like protein  TssE
27ECOPMV1_030973173264..3174640 [+], 1377544577354hypothetical protein  TssA
28ECOPMV1_03098 (serA_1)3174942..3175889 [-], 948544577355D-3-phosphoglycerate dehydrogenase 
29ECOPMV1_03099 (kdsD_1)3175961..3176557 [-], 597544577356Arabinose 5-phosphate isomerase KdsD 
30ECOPMV1_03100 (malY_2)3176560..3177009 [-], 450544577357hypothetical protein 
31ECOPMV1_03101 (malY_3)3177066..3177734 [-], 669544577358hypothetical protein 
32ECOPMV1_03102 (glcB_1)3177734..3179314 [-], 1581544577359PTS system glucoside-specific EIICBA component 
 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.
 






2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.
 






3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.
 







Homology Effector list
EC042_4529 , AHW84487

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1ECOPMV1_03080(hcpA_3)3150723..3151214 [+], 492544577337Secreted protein hcp EC042_4529
2ECOPMV1_030833156563..3158332 [+], 1770544577340PGAP1-like protein AHW84487

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Proteins        Genes

Homology Immunity protein list
AHW84488

Immunity protein identified
#Locus tag(Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1ECOPMV1_030843158307..3159140 [+], 834544577341hypothetical protein AHW84488

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Proteins        Genes
N/A