I. Summary
SecReT6 ID893 insolico
StrainPseudomonas aeruginosa SCV20265
Repliconchromosome [Browse all T6SS(s) in this replicon]
T6SS TypeType i; subtype i3
insolico Bioinformatics investigation has been performed on this T6SS.

II. T6SS components
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III. genome coordinates of the T6SS gene cluster
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProductNote
1SCV20265_007587168..90266 [-], 3099568306814Serine/threonine protein kinase PpkA  PpkA
2SCV20265_007690274..91002 [-], 729568306815Phosphoprotein phosphatase PppA  PppA
3SCV20265_007791012..91692 [-], 681568306816Protein phosphatase ImpM  TagF
4SCV20265_007891689..95219 [-], 3531568306817IcmF-related protein  TssM
5SCV20265_007995216..96565 [-], 1350568306818Outer membrane protein ImpK  TssL
6SCV20265_008096572..97906 [-], 1335568306819Uncharacterized protein ImpJ/VasE  TssK
7SCV20265_008197922..98386 [-], 465568306820Type VI secretion lipoprotein VasD  TssJ
8SCV20265_008298431..99954 [-], 1524568306821Uncharacterized protein ImpI/VasC  Fha
9SCV20265_008399964..100086 [+], 123568306822Hypothetical protein 
10SCV20265_0084100322..101356 [+], 1035568306823Uncharacterized protein ImpA  TssA
11SCV20265_0085101445..101963 [+], 519568306824Uncharacterized protein ImpB  TssB
12SCV20265_0086101976..103472 [+], 1497568306825Uncharacterized protein ImpC  TssC
13SCV20265_0087103560..104036 [+], 477568306826Uncharacterized protein ImpD  TssD
14SCV20265_0088104264..105049 [+], 786568306827Protein of avirulence locus ImpE  TagJ
15SCV20265_0089105051..105560 [+], 510568306828Uncharacterized protein ImpF  TssE
16SCV20265_0090105557..107416 [+], 1860568306829Protein ImpG/VasA  TssF
17SCV20265_0091107380..108426 [+], 1047568306830Uncharacterized protein ImpH/VasB  TssG
18SCV20265_0092108419..111127 [+], 2709568306831ClpB protein  TssH
19SCV20265_0093111165..113105 [+], 1941568306832VgrG protein  TssI
20SCV20265_0094113220..113504 [-], 285568306833Phosphoglycerate dehydrogenase  Tsi6 (i)
21SCV20265_0095113501..114793 [-], 1293568306834Rhs family protein  Tse6 (e)
22SCV20265_0096114809..115243 [-], 435568306835Hypothetical protein 
23SCV20265_0097115497..117722 [+], 2226568306836VgrG protein  TssI
24SCV20265_0098117810..118199 [+], 390568306837Hypothetical protein 
25SCV20265_0099118216..119328 [+], 1113568306838Hypothetical protein 
26SCV20265_0100119325..120362 [+], 10385683068393-oxoacyl-ACP synthase 
27SCV20265_0101120362..121522 [+], 1161568306840Hypothetical protein  PA0099 (e)
28SCV20265_0102121544..122464 [+], 921568306841Hypothetical protein 
flank Genes in the 5-kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any. In the 'Note' column,if available, '(e)' denotes effector while '(i)' for immunity protein

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Proteins        Genes

V. Investigation of the genomic context of the T6SS gene cluster.
1. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the mobile genetic elements database, ACLAME.

2. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against the virulence factor database, VFDB.

3. BLASTp searches of the proteins encoded by T6SS gene cluster and its flanking regions against against the antibiotic resistance database, ARDB.

Homology Effector list
PA0085 , PA0091, PA0093, PA0095, PA0099, PA3484, PA2774, PA2702, PA2685, PA2684, PA1844

Effector identified
#Locus tag (Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1SCV20265_0087103560..104036 [+], 477568306826Uncharacterized protein ImpD PA0085
2SCV20265_0093111165..113105 [+], 1941568306832VgrG protein PA0091
3SCV20265_0095113501..114793 [-], 1293568306834Rhs family protein PA0093
4SCV20265_0097115497..117722 [+], 2226568306836VgrG protein PA0095
5SCV20265_0101120362..121522 [+], 1161568306840Hypothetical protein PA0099
6SCV20265_15581640711..1641937 [-], 1227568308297Hypothetical protein PA3484
7SCV20265_24532559199..2559786 [+], 588568309192Hypothetical protein PA2774
8SCV20265_25462640752..2641228 [-], 477568309285Hypothetical protein PA2702
9SCV20265_25632658924..2660993 [+], 2070568309302VgrG protein PA2685
10SCV20265_25642661043..2664996 [+], 3954568309303Hypothetical protein PA2684
11SCV20265_35563806197..3806661 [+], 465568310293Hypothetical protein PA1844

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Proteins        Genes

Homology Immunity protein list
PA0092, PA3485, PA2775, PA2703, Tsi5, PA1845

Immunity protein identified
#Locus tag(Gene)Coordinates [+/-], size (bp)Protein GIProduct  Homolog
1SCV20265_0094113220..113504 [-], 285568306833Phosphoglycerate dehydrogenase PA0092
2SCV20265_15571640277..1640714 [-], 438568308296Hypothetical protein PA3485
3SCV20265_24522558757..2559194 [+], 438568309191Hypothetical protein PA2775
4SCV20265_25452640509..2640742 [-], 234568309284Hypothetical protein PA2703
5SCV20265_25652664993..2665184 [+], 192568309304Hypothetical protein Tsi5
6SCV20265_35553805637..3806155 [+], 519568310292Hypothetical protein PA1845

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Proteins        Genes